TW200540185A - Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell - Google Patents

Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell Download PDF

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Publication number
TW200540185A
TW200540185A TW094101799A TW94101799A TW200540185A TW 200540185 A TW200540185 A TW 200540185A TW 094101799 A TW094101799 A TW 094101799A TW 94101799 A TW94101799 A TW 94101799A TW 200540185 A TW200540185 A TW 200540185A
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TW
Taiwan
Prior art keywords
nucleic acid
acid sequence
ser
val
seq
Prior art date
Application number
TW094101799A
Other languages
English (en)
Chinese (zh)
Inventor
Jan Lehmbeck
Fredrik Wahlbom
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Publication of TW200540185A publication Critical patent/TW200540185A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
TW094101799A 2004-01-21 2005-01-21 Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell TW200540185A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200400077 2004-01-21
DKPA200400174 2004-02-05
DKPA200400761 2004-05-12

Publications (1)

Publication Number Publication Date
TW200540185A true TW200540185A (en) 2005-12-16

Family

ID=34811629

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094101799A TW200540185A (en) 2004-01-21 2005-01-21 Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell

Country Status (7)

Country Link
EP (1) EP1711529A1 (fr)
JP (1) JP2007535913A (fr)
AR (1) AR047440A1 (fr)
AU (1) AU2005206251A1 (fr)
CA (1) CA2553731A1 (fr)
TW (1) TW200540185A (fr)
WO (1) WO2005070962A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004203727C1 (en) 2003-01-07 2008-08-21 Symphogen A/S Method for manufacturing recombinant polyclonal proteins
EP1729797B1 (fr) 2004-03-22 2008-09-10 Solvay Pharmaceuticals GmbH Compositions pharmaceutiques par voie orale a base de lipases, en particulier de pancreatine, contenant des tensioacitfs
WO2007014896A1 (fr) 2005-07-29 2007-02-08 Solvay Pharmaceuticals Gmbh Procédé de fabrication de poudre de pancréatine stérilisée
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
CA3081308C (fr) 2006-12-21 2024-02-20 Novozymes A/S Variantes lipasiques pour une utilisation pharmaceutique
US20100062491A1 (en) * 2007-01-05 2010-03-11 Novozymes A/S Overexpression of the Chaperone BIP in a Heterokaryon
CN102292444A (zh) 2008-11-20 2011-12-21 诺维信股份有限公司 具有淀粉分解增强活性的多肽和编码该多肽的多核苷酸
CN102300986A (zh) 2008-12-04 2011-12-28 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011059740A1 (fr) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides ayant une activité cellobiohydrolase et polynucléotides codant pour ceux-ci
EP2585601A1 (fr) 2010-06-25 2013-05-01 Novozymes A/S Polynucléotides présentant une activité de promoteur
EP2585591B1 (fr) 2010-06-25 2014-12-24 Novozymes A/S Polynucléotides dotés d'une fonction de séquence de guidage
EP2585602A1 (fr) 2010-06-25 2013-05-01 Novozymes A/S Polynucléotides présentant une activité de promoteur
EP2646558B1 (fr) 2010-11-30 2016-07-20 Novozymes, Inc. Promoteurs pour exprimer des gènes dans une cellule fongique
CA2820248C (fr) 2010-12-07 2019-10-29 Vnomics Corp. Systeme et procede permettant de mesurer et de reduire le gaspillage de carburant d'un vehicule
US20130302878A1 (en) 2011-01-20 2013-11-14 Novozymes A/S Expression of plant peroxidases in filamentous fungi
EP2527432A1 (fr) 2011-05-23 2012-11-28 Novozymes A/S Marqueur de sélection bidirectionnelle codant pour la cytosine désaminase
EP2527448A1 (fr) 2011-05-23 2012-11-28 Novozymes A/S Intégrations simultanées spécifiques au site de copies de plusieurs gènes dans des champignons filamenteux
WO2013076259A2 (fr) 2011-11-25 2013-05-30 Novozymes A/S Polypeptides ayant une activité de lysozyme et polynucléotides codant pour ces polypeptides
KR101660580B1 (ko) 2014-04-02 2016-09-28 프레스티지 바이오파마 피티이. 엘티디. 항체의 당 함량 조절을 통한 항체의 제조 방법
EP3592762A4 (fr) * 2017-03-10 2020-12-30 Bolt Threads, Inc. Compositions et procédés de production de rendements sécrétés élevés de protéines recombinées
KR102638074B1 (ko) 2017-03-10 2024-02-20 볼트 쓰레즈, 인크. 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법
WO2019046703A1 (fr) 2017-09-01 2019-03-07 Novozymes A/S Procédés d'amélioration de l'édition du génome dans des champignons
CN115427560A (zh) 2020-03-12 2022-12-02 诺维信公司 使用无催化活性rna指导的内切核酸酶的crispr-aid
CN116234814A (zh) * 2020-08-28 2023-06-06 江苏恒瑞医药股份有限公司 用于降低异源多肽末端异质性的信号肽

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5643745A (en) * 1994-02-03 1997-07-01 University Of Hawaii Heterologous dimeric proteins produced in heterokaryons
US5683899A (en) * 1994-02-03 1997-11-04 University Of Hawaii Methods and compositions for combinatorial-based discovery of new multimeric molecules
US20040018573A1 (en) * 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
CN1756767A (zh) * 2003-02-06 2006-04-05 诺和酶股份有限公司 在丝状真菌中表达人重链抗体
WO2007045248A1 (fr) * 2005-10-17 2007-04-26 Novozymes A/S Utilisation de mutants fongiques pour l'expression des anticorps

Also Published As

Publication number Publication date
EP1711529A1 (fr) 2006-10-18
WO2005070962A1 (fr) 2005-08-04
JP2007535913A (ja) 2007-12-13
CA2553731A1 (fr) 2005-08-04
AR047440A1 (es) 2006-01-18
AU2005206251A1 (en) 2005-08-04

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