TW200516251A - Chemical encoding technology for combinatorial synthesis - Google Patents
Chemical encoding technology for combinatorial synthesisInfo
- Publication number
- TW200516251A TW200516251A TW092130788A TW92130788A TW200516251A TW 200516251 A TW200516251 A TW 200516251A TW 092130788 A TW092130788 A TW 092130788A TW 92130788 A TW92130788 A TW 92130788A TW 200516251 A TW200516251 A TW 200516251A
- Authority
- TW
- Taiwan
- Prior art keywords
- combinatorial synthesis
- encoding technology
- chemical encoding
- chemical
- substituents
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
- C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Structural Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42361902P | 2002-11-04 | 2002-11-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200516251A true TW200516251A (en) | 2005-05-16 |
Family
ID=32312689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW092130788A TW200516251A (en) | 2002-11-04 | 2003-11-04 | Chemical encoding technology for combinatorial synthesis |
Country Status (4)
Country | Link |
---|---|
US (1) | US20040146941A1 (zh) |
AU (1) | AU2003291691A1 (zh) |
TW (1) | TW200516251A (zh) |
WO (1) | WO2004041752A2 (zh) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
EP2240452B1 (en) | 2008-01-04 | 2019-05-29 | Intellikine, LLC | 1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives as pi3 kinase modulators, their compositions and uses |
DK2383266T3 (da) * | 2009-01-09 | 2013-11-04 | Mitsubishi Gas Chemical Co | Glycolforbindelse med dioxanstruktur samt fremgangsmåde til dens fremstilling |
WO2010079809A1 (ja) | 2009-01-09 | 2010-07-15 | 三菱瓦斯化学株式会社 | ジオキサン構造を有するグリコール化合物及びその製造方法 |
US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
SG10201913594UA (en) | 2010-04-22 | 2020-02-27 | Vertex Pharma | Process of producing cycloalkylcarboxamido-indole compounds |
NZ612909A (en) | 2011-01-10 | 2015-09-25 | Infinity Pharmaceuticals Inc | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
CN102675092B (zh) * | 2011-03-14 | 2014-11-05 | 江苏中丹药物研究有限公司 | 一种制备2-芳基-2,2-二甲基乙酸甲酯的方法 |
US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
CA2885796C (en) * | 2012-09-24 | 2022-05-03 | Allozyne, Inc. | Cell lines |
SG11201507104WA (en) | 2013-03-15 | 2015-10-29 | Medimmune Ltd | Novel nucleic acid molecules |
LT3424534T (lt) | 2014-04-15 | 2021-11-10 | Vertex Pharmaceuticals Incorporated | Farmacinės kompozicijos, skirtos gydyti ligas, kurių atsiradimui tarpininkauja cistinės fibrozės transmembraninio laidumo reguliatorius |
US20150320755A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
WO2016160475A1 (en) * | 2015-03-30 | 2016-10-06 | Genapsys, Inc. | Beads for nucleic acid sequencing |
SG11201811237WA (en) | 2016-06-24 | 2019-01-30 | Infinity Pharmaceuticals Inc | Combination therapies |
CN111704711B (zh) * | 2019-03-18 | 2022-04-08 | 中国科学院宁波材料技术与工程研究所 | 一种基于缩醛结构的环氧单体及其制备方法与应用 |
TW202245800A (zh) | 2020-02-18 | 2022-12-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
CN115135383B (zh) | 2020-02-18 | 2024-06-11 | 吉利德科学公司 | 抗病毒化合物 |
WO2022115645A1 (en) | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
JP2024512771A (ja) | 2021-04-16 | 2024-03-19 | ギリアード サイエンシーズ, インコーポレイテッド | アミドを使用してカルバヌクレオシドを調製する方法 |
WO2023230587A2 (en) | 2022-05-25 | 2023-11-30 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5565324A (en) * | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
US6541203B2 (en) * | 1998-11-23 | 2003-04-01 | President And Fellows Of Harvard College | Detecting structural or synthetic information about chemical compounds |
US6322980B1 (en) * | 1999-04-30 | 2001-11-27 | Aclara Biosciences, Inc. | Single nucleotide detection using degradation of a fluorescent sequence |
-
2003
- 2003-11-03 US US10/698,932 patent/US20040146941A1/en not_active Abandoned
- 2003-11-04 WO PCT/US2003/034964 patent/WO2004041752A2/en not_active Application Discontinuation
- 2003-11-04 AU AU2003291691A patent/AU2003291691A1/en not_active Abandoned
- 2003-11-04 TW TW092130788A patent/TW200516251A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004041752A3 (en) | 2005-10-06 |
AU2003291691A8 (en) | 2004-06-07 |
WO2004041752A2 (en) | 2004-05-21 |
AU2003291691A1 (en) | 2004-06-07 |
US20040146941A1 (en) | 2004-07-29 |
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