TW200512000A - 2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis - Google Patents

2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis

Info

Publication number
TW200512000A
TW200512000A TW093127917A TW93127917A TW200512000A TW 200512000 A TW200512000 A TW 200512000A TW 093127917 A TW093127917 A TW 093127917A TW 93127917 A TW93127917 A TW 93127917A TW 200512000 A TW200512000 A TW 200512000A
Authority
TW
Taiwan
Prior art keywords
alkylidene
vitamin
osteopenia
derivatives
treatment
Prior art date
Application number
TW093127917A
Other languages
English (en)
Inventor
Judith Lee Campagnari
Andrew George Lee
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TW200512000A publication Critical patent/TW200512000A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW093127917A 2003-09-19 2004-09-15 2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis TW200512000A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50450803P 2003-09-19 2003-09-19

Publications (1)

Publication Number Publication Date
TW200512000A true TW200512000A (en) 2005-04-01

Family

ID=34375510

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093127917A TW200512000A (en) 2003-09-19 2004-09-15 2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis

Country Status (17)

Country Link
US (1) US20050065125A1 (zh)
EP (1) EP1667690A1 (zh)
JP (1) JP2007505884A (zh)
KR (1) KR20060058135A (zh)
CN (1) CN100413507C (zh)
AU (1) AU2004273667A1 (zh)
BR (1) BRPI0414465A (zh)
CA (1) CA2539358A1 (zh)
HK (1) HK1092063A1 (zh)
IL (1) IL173653A0 (zh)
MX (1) MXPA06003156A (zh)
NO (1) NO20060655L (zh)
NZ (1) NZ545393A (zh)
RU (1) RU2006108528A (zh)
TW (1) TW200512000A (zh)
WO (1) WO2005027917A1 (zh)
ZA (1) ZA200602258B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008532549A (ja) 2005-03-15 2008-08-21 アラーガン、インコーポレイテッド 内因性クロストリジウム毒素受容体系に対する増大した標的能力を有する修飾クロストリジウム毒素
US20120207742A1 (en) 2011-02-14 2012-08-16 Allergan, Inc. Treatments Using PSMA Ligand Endopeptidases
CN106974078A (zh) * 2017-03-22 2017-07-25 广东海洋大学 25‑oh‑d3促进21‑42日龄白羽肉鸡胫骨发育的应用
CN106857403A (zh) * 2017-03-22 2017-06-20 广东海洋大学 25‑oh‑d3促进1‑21日龄白羽肉鸡胫骨发育的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
EP0619306B1 (en) * 1993-04-05 1996-09-11 Wisconsin Alumni Research Foundation 19-Nor-vitamin D3 compounds with substituent at 2-position
US6316642B1 (en) * 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
WO2001056981A1 (en) * 2000-01-31 2001-08-09 Leo Pharma A/S Use of vitamin d-derivatives in the treatment of osteoporosis and related bone disorders, as well as novel vitamin d3-derivatives
EP1286962B1 (en) * 2000-05-31 2008-06-25 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds
US20030195175A1 (en) * 2002-03-25 2003-10-16 Deluca Hector F. Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone

Also Published As

Publication number Publication date
CA2539358A1 (en) 2005-03-31
CN1852717A (zh) 2006-10-25
US20050065125A1 (en) 2005-03-24
NZ545393A (en) 2009-10-30
IL173653A0 (en) 2006-07-05
KR20060058135A (ko) 2006-05-29
EP1667690A1 (en) 2006-06-14
ZA200602258B (en) 2007-11-28
JP2007505884A (ja) 2007-03-15
CN100413507C (zh) 2008-08-27
WO2005027917A1 (en) 2005-03-31
AU2004273667A1 (en) 2005-03-31
NO20060655L (no) 2006-06-16
BRPI0414465A (pt) 2006-11-14
MXPA06003156A (es) 2006-06-05
RU2006108528A (ru) 2006-07-27
HK1092063A1 (en) 2007-02-02

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