TR201906117T4 - Nitrokatesollere yönelik uygulama rejimi. - Google Patents
Nitrokatesollere yönelik uygulama rejimi. Download PDFInfo
- Publication number
- TR201906117T4 TR201906117T4 TR2019/06117T TR201906117T TR201906117T4 TR 201906117 T4 TR201906117 T4 TR 201906117T4 TR 2019/06117 T TR2019/06117 T TR 2019/06117T TR 201906117 T TR201906117 T TR 201906117T TR 201906117 T4 TR201906117 T4 TR 201906117T4
- Authority
- TR
- Turkey
- Prior art keywords
- nitrocatalyls
- application regime
- regime
- application
- substituents
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
Mevcut buluş, formülün (I) bileşiklerine yönelik yeni doz rejimleri ile ilgilidir: burada sübstitüeler tarifnamede belirtildiği gibidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13724808P | 2008-07-29 | 2008-07-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201906117T4 true TR201906117T4 (tr) | 2019-05-21 |
Family
ID=41130570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/06117T TR201906117T4 (tr) | 2008-07-29 | 2009-07-29 | Nitrokatesollere yönelik uygulama rejimi. |
Country Status (17)
Country | Link |
---|---|
US (1) | US20110301204A1 (tr) |
EP (1) | EP2307020B1 (tr) |
JP (2) | JP6165412B2 (tr) |
KR (3) | KR20190079705A (tr) |
CN (1) | CN102355900A (tr) |
AR (1) | AR072846A1 (tr) |
AU (1) | AU2009277196B2 (tr) |
BR (1) | BRPI0913913A2 (tr) |
CA (1) | CA2729288C (tr) |
DK (1) | DK2307020T3 (tr) |
ES (1) | ES2723729T3 (tr) |
IL (1) | IL210393A0 (tr) |
MX (2) | MX360330B (tr) |
PT (1) | PT2307020T (tr) |
RU (1) | RU2557532C2 (tr) |
TR (1) | TR201906117T4 (tr) |
WO (1) | WO2010014025A1 (tr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8168793B2 (en) | 2005-07-26 | 2012-05-01 | Portela & Ca., S.A. | Nitrocatechol derivatives as COMT inhibitors |
EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
ES2597705T3 (es) | 2007-01-31 | 2017-01-20 | Bial - Portela & Ca., S.A. | Derivados de nitrocatecol como inhibidores de COMT administrados con un régimen de dosificación específico |
ES2565080T3 (es) | 2008-03-17 | 2016-03-31 | Bial-Portela & Ca, S.A. | Formas cristalinas de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3-il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol |
PT2413912T (pt) * | 2009-04-01 | 2019-06-11 | Bial Portela & Ca Sa | Formulações farmacêuticas compreendendo derivados de nitrocatecol e métodos para as produzir |
KR20120092175A (ko) | 2009-12-04 | 2012-08-20 | 죤 이. 그랜트 | 카테콜-0-메틸-트랜스퍼라제 저해제를 사용한 충동 제어 장애의 치료 |
US20140045900A1 (en) * | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
PL2791134T3 (pl) | 2011-12-13 | 2020-03-31 | BIAL - PORTELA & Cª S.A. | Związek chemiczny użyteczny jako związek pośredni do wytwarzania inhibitora katechol-o-metylotransferazy |
JP2018500300A (ja) | 2014-11-28 | 2018-01-11 | ノヴィファーマ,エス.アー. | パーキンソン病を遅延させるための医薬 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10338174A1 (de) * | 2003-08-20 | 2005-03-24 | Lts Lohmann Therapie-Systeme Ag | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
US20060173074A1 (en) * | 2004-11-10 | 2006-08-03 | Juha Ellmen | Treatment of restless legs syndrome |
KR20080027463A (ko) * | 2005-05-18 | 2008-03-27 | 아덱스 파마 에스에이 | 대사성 글루타메이트 수용체의 양성 알로스테릭조절자로서의 치환된 옥사디아졸 유도체 |
US8168793B2 (en) * | 2005-07-26 | 2012-05-01 | Portela & Ca., S.A. | Nitrocatechol derivatives as COMT inhibitors |
EP1845097A1 (en) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
ES2597705T3 (es) * | 2007-01-31 | 2017-01-20 | Bial - Portela & Ca., S.A. | Derivados de nitrocatecol como inhibidores de COMT administrados con un régimen de dosificación específico |
ES2565080T3 (es) * | 2008-03-17 | 2016-03-31 | Bial-Portela & Ca, S.A. | Formas cristalinas de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3-il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol |
-
2009
- 2009-07-29 AU AU2009277196A patent/AU2009277196B2/en not_active Ceased
- 2009-07-29 ES ES09788437T patent/ES2723729T3/es active Active
- 2009-07-29 MX MX2015018058A patent/MX360330B/es unknown
- 2009-07-29 KR KR1020197018533A patent/KR20190079705A/ko not_active IP Right Cessation
- 2009-07-29 EP EP09788437.3A patent/EP2307020B1/en active Active
- 2009-07-29 MX MX2011001046A patent/MX2011001046A/es not_active Application Discontinuation
- 2009-07-29 KR KR1020107029508A patent/KR20110044949A/ko active Search and Examination
- 2009-07-29 US US13/002,287 patent/US20110301204A1/en not_active Abandoned
- 2009-07-29 DK DK09788437.3T patent/DK2307020T3/da active
- 2009-07-29 KR KR1020187023723A patent/KR20180095135A/ko not_active Application Discontinuation
- 2009-07-29 AR ARP090102886A patent/AR072846A1/es unknown
- 2009-07-29 TR TR2019/06117T patent/TR201906117T4/tr unknown
- 2009-07-29 PT PT09788437T patent/PT2307020T/pt unknown
- 2009-07-29 WO PCT/PT2009/000044 patent/WO2010014025A1/en active Application Filing
- 2009-07-29 CA CA2729288A patent/CA2729288C/en active Active
- 2009-07-29 JP JP2011521064A patent/JP6165412B2/ja active Active
- 2009-07-29 CN CN2009801261379A patent/CN102355900A/zh active Pending
- 2009-07-29 RU RU2010154173/15A patent/RU2557532C2/ru active
- 2009-07-29 BR BRPI0913913A patent/BRPI0913913A2/pt not_active Application Discontinuation
-
2010
- 2010-12-30 IL IL210393A patent/IL210393A0/en unknown
-
2015
- 2015-02-26 JP JP2015036568A patent/JP6518080B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP2011529489A (ja) | 2011-12-08 |
MX360330B (es) | 2018-10-30 |
CN102355900A (zh) | 2012-02-15 |
JP2015129163A (ja) | 2015-07-16 |
US20110301204A1 (en) | 2011-12-08 |
EP2307020A1 (en) | 2011-04-13 |
KR20190079705A (ko) | 2019-07-05 |
AR072846A1 (es) | 2010-09-22 |
CA2729288A1 (en) | 2010-02-04 |
RU2010154173A (ru) | 2012-09-10 |
JP6165412B2 (ja) | 2017-07-19 |
MX2011001046A (es) | 2011-03-29 |
CA2729288C (en) | 2017-01-17 |
JP6518080B2 (ja) | 2019-05-22 |
KR20110044949A (ko) | 2011-05-03 |
KR20180095135A (ko) | 2018-08-24 |
WO2010014025A1 (en) | 2010-02-04 |
PT2307020T (pt) | 2019-05-28 |
AU2009277196A1 (en) | 2010-02-04 |
IL210393A0 (en) | 2011-03-31 |
ES2723729T3 (es) | 2019-08-30 |
DK2307020T3 (da) | 2019-05-13 |
BRPI0913913A2 (pt) | 2015-10-13 |
EP2307020B1 (en) | 2019-02-20 |
RU2557532C2 (ru) | 2015-07-20 |
AU2009277196B2 (en) | 2015-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR201906117T4 (tr) | Nitrokatesollere yönelik uygulama rejimi. | |
CY1119515T1 (el) | Οξαζολο υποκατεστημενα ινδαζολια ως αναστολεις ρι3-κινασης | |
MX2010009416A (es) | Compuestos heterociclicos como inhibidores de cxcr2. | |
MY160490A (en) | Arylethynyl derivatives | |
BR112014030473A2 (pt) | novo diazaespirocicloalcano e azaespirocicloalcano | |
CO6321282A2 (es) | Derivados de piperidinilindol como inhibidores de aldosterona sintasa | |
PH12014502169A1 (en) | N-cyclylamides as nematicides | |
UA114087C2 (xx) | Похідні піридину | |
TR201903981T4 (tr) | Kanser tedavisi için bileşikler. | |
MY169043A (en) | New dihydroquinoline-2-one derivatives | |
EA201291317A1 (ru) | Тетрагидропиридопиримидиновые производные | |
ATE427927T1 (de) | Phenylacetylenderivate mit affinitat zum mglur5- rezeptor | |
DE602006009789D1 (de) | Acetylenderivate | |
BRPI0812222A2 (pt) | Compostos ciclobutenodiona substituídos anti-inflamatórios. | |
UA110600C2 (uk) | Спосіб отримання захищених похідних l-аланіну | |
SV2011003800A (es) | Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica | |
EA201101148A1 (ru) | Новые гербициды | |
UA106880C2 (uk) | Нові гербіциди | |
EA201490846A1 (ru) | Новые производные арилхинолина | |
EA201101146A1 (ru) | Новые гербициды | |
EA200900090A1 (ru) | Бензиламины, способ их получения и их применение в качестве противовоспалительных средств | |
EA201270256A1 (ru) | Производные т1-замещенного 5-фтор-2-оксопиримидинон-1 (2h) -карбоксамида | |
CR20130431A (es) | 5-(fenil)/piridinil-etinil)-2-piridina/ 2-pirimidina-carboxamidas como moduladores de mglur5 | |
NO20081207L (no) | Isoquinolines as IGF-1R inhibitors | |
EA201391214A1 (ru) | Композиции, содержащие алкилалкоксисульфонаты, для производства термостабильных пен |