TR201722630A2 - - Google Patents
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- Publication number
- TR201722630A2 TR201722630A2 TR2017/22630A TR201722630A TR201722630A2 TR 201722630 A2 TR201722630 A2 TR 201722630A2 TR 2017/22630 A TR2017/22630 A TR 2017/22630A TR 201722630 A TR201722630 A TR 201722630A TR 201722630 A2 TR201722630 A2 TR 201722630A2
- Authority
- TR
- Turkey
- Prior art keywords
- pharmaceutically acceptable
- dabigatran etexilate
- oral administration
- free base
- relates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/22630A TR201722630A2 (enExample) | 2017-12-28 | 2017-12-28 | |
| PCT/TR2018/050919 WO2019151966A2 (en) | 2017-12-28 | 2018-12-27 | Pharmaceutical tablet compositions of dabigatran |
| EP18899013.9A EP3731824B1 (en) | 2017-12-28 | 2018-12-27 | Pharmaceutical tablet compositions of dabigatran |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/22630A TR201722630A2 (enExample) | 2017-12-28 | 2017-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201722630A2 true TR201722630A2 (enExample) | 2019-07-22 |
Family
ID=67180856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2017/22630A TR201722630A2 (enExample) | 2017-12-28 | 2017-12-28 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3731824B1 (enExample) |
| TR (1) | TR201722630A2 (enExample) |
| WO (1) | WO2019151966A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY39094A (es) * | 2020-02-27 | 2021-07-30 | Hk Inno N Corp | Composición farmacéutica que comprende compuesto derivado de bencimidazol |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE121699A1 (es) | 1997-02-18 | 1999-12-08 | Boehringer Ingelheim Pharma | Heterociclos biciclicos disustituidos como inhibidores de la trombina |
| ES2380704T3 (es) * | 2002-03-07 | 2012-05-17 | Boehringer Ingelheim International Gmbh | Metanosulfonato de éster etílico de ácido 3-[(2-{[4-(hexiloxicarbonilamino--imino-metil)-fenilamino]-metil}-1-metil-1H-bencimidazol-5-carb3onil)-piridin-2-il-amino]-propiónico |
| DE10337697A1 (de) | 2003-08-16 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tablette enthaltend 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenyl-amino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester oder dessen Salze |
| DE102005020002A1 (de) | 2005-04-27 | 2006-11-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Physiologisch verträgliche Salze von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester |
| EP2588090B2 (en) | 2010-07-01 | 2023-11-22 | KRKA, tovarna zdravil, d.d., Novo mesto | Pharmaceutical oral dosage forms comprising dabigatran etexilate and its pharmaceutically acceptable salts |
| EP2649060B1 (en) | 2010-12-06 | 2017-04-05 | MSN Laboratories Limited | Process for the preparation of benzimidazole derivatives and its salts |
| AU2013224146B2 (en) | 2012-02-21 | 2017-06-08 | Towa Pharmaceutical Europe, S.L. | Oral pharmaceutical compositions of dabigatran etexilate |
| WO2015145462A1 (en) * | 2014-03-26 | 2015-10-01 | Cadila Healthcare Limited | Pharmaceutical compositions of dabigatran |
| CN105919962B (zh) * | 2015-12-18 | 2019-01-18 | 重庆两江药物研发中心有限公司 | 一种达比加群酯片剂及其制备方法 |
| WO2018104387A1 (en) * | 2016-12-07 | 2018-06-14 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Multilayered tablet compositions of dabigatran |
-
2017
- 2017-12-28 TR TR2017/22630A patent/TR201722630A2/tr unknown
-
2018
- 2018-12-27 WO PCT/TR2018/050919 patent/WO2019151966A2/en not_active Ceased
- 2018-12-27 EP EP18899013.9A patent/EP3731824B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019151966A3 (en) | 2019-10-10 |
| WO2019151966A2 (en) | 2019-08-08 |
| EP3731824A2 (en) | 2020-11-04 |
| EP3731824B1 (en) | 2023-03-15 |
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