TR201722630A2 - - Google Patents
Download PDFInfo
- Publication number
- TR201722630A2 TR201722630A2 TR2017/22630A TR201722630A TR201722630A2 TR 201722630 A2 TR201722630 A2 TR 201722630A2 TR 2017/22630 A TR2017/22630 A TR 2017/22630A TR 201722630 A TR201722630 A TR 201722630A TR 201722630 A2 TR201722630 A2 TR 201722630A2
- Authority
- TR
- Turkey
- Prior art keywords
- pharmaceutically acceptable
- dabigatran etexilate
- oral administration
- free base
- relates
- Prior art date
Links
- 229960000288 dabigatran etexilate Drugs 0.000 abstract 2
- KSGXQBZTULBEEQ-UHFFFAOYSA-N dabigatran etexilate Chemical compound C1=CC(C(N)=NC(=O)OCCCCCC)=CC=C1NCC1=NC2=CC(C(=O)N(CCC(=O)OCC)C=3N=CC=CC=3)=CC=C2N1C KSGXQBZTULBEEQ-UHFFFAOYSA-N 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007916 tablet composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Mevcut buluş, dabigatran eteksilat serbest bazını veya dabigatran eteksilatın farmasötik olarak kabul edilebilir tuzlarını ve en az bir farmasötik olarak kabul edilebilir eksipiyan içeren, oral uygulamaya yönelik farmasötik tablet kompozisyonları ile ilgilidir.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TR2017/22630A TR201722630A2 (tr) | 2017-12-28 | 2017-12-28 | |
EP18899013.9A EP3731824B1 (en) | 2017-12-28 | 2018-12-27 | Pharmaceutical tablet compositions of dabigatran |
PCT/TR2018/050919 WO2019151966A2 (en) | 2017-12-28 | 2018-12-27 | Pharmaceutical tablet compositions of dabigatran |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TR2017/22630A TR201722630A2 (tr) | 2017-12-28 | 2017-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201722630A2 true TR201722630A2 (tr) | 2019-07-22 |
Family
ID=67180856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2017/22630A TR201722630A2 (tr) | 2017-12-28 | 2017-12-28 |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3731824B1 (tr) |
TR (1) | TR201722630A2 (tr) |
WO (1) | WO2019151966A2 (tr) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE121699A1 (es) | 1997-02-18 | 1999-12-08 | Boehringer Ingelheim Pharma | Heterociclos biciclicos disustituidos como inhibidores de la trombina |
DK1485094T4 (da) * | 2002-03-07 | 2020-06-22 | Boehringer Ingelheim Int | Doseringsform til oral indgivelse af 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsyre-ethylester eller dets salte |
DE10337697A1 (de) | 2003-08-16 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tablette enthaltend 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenyl-amino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester oder dessen Salze |
DE102005020002A1 (de) | 2005-04-27 | 2006-11-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Physiologisch verträgliche Salze von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester |
US20130177652A1 (en) | 2010-07-01 | 2013-07-11 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Pharmaceutical oral dosage forms comprising dabigatran etexilate and its pharmaceutically acceptable salts |
WO2012077136A2 (en) | 2010-12-06 | 2012-06-14 | Msn Laboratories Limited | Process for the preparation of benzimidazole derivatives and its salts |
EP3858337A3 (en) | 2012-02-21 | 2021-09-29 | Towa Pharmaceutical Europe, S.L. | Oral pharmaceutical compositions of dabigatran etexilate |
IN2014MU01042A (tr) * | 2014-03-26 | 2015-10-02 | Cadila Healthcare Ltd | |
CN105919962B (zh) * | 2015-12-18 | 2019-01-18 | 重庆两江药物研发中心有限公司 | 一种达比加群酯片剂及其制备方法 |
EP3332771A1 (en) * | 2016-12-07 | 2018-06-13 | Sanovel Ilac Sanayi ve Ticaret A.S. | Multilayered tablet compositions of dabigatran |
-
2017
- 2017-12-28 TR TR2017/22630A patent/TR201722630A2/tr unknown
-
2018
- 2018-12-27 WO PCT/TR2018/050919 patent/WO2019151966A2/en unknown
- 2018-12-27 EP EP18899013.9A patent/EP3731824B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2019151966A3 (en) | 2019-10-10 |
EP3731824B1 (en) | 2023-03-15 |
WO2019151966A2 (en) | 2019-08-08 |
EP3731824A2 (en) | 2020-11-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1124007T1 (el) | Στοματικες δοσολογικες μορφες παρατεταμενης απελευθερωσης τοφασιτινιμπης | |
MX2020004932A (es) | Compuestos utiles para inhibir a cdk7. | |
MA41265B1 (fr) | Compositions pour administration de médicaments iléo-jéjunal. | |
DOP2016000156A (es) | Composiciones farmacã¿uticas que comprenden azd9291. | |
CY1122024T1 (el) | Ενωσεις αναστολης σηματοδοτησης μονοπατιου notch | |
EA201792592A1 (ru) | Фармацевтические препараты, содержащие тенофовир и эмтрицитабин | |
EA201992116A1 (ru) | Фармацевтические составы флороглюцинола и триметилфлороглюцинола | |
EA201792591A1 (ru) | Фармацевтические препараты | |
TR201821116A2 (tr) | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ | |
TR201906685T4 (tr) | Kristalin macitentan içeren farmasötik bileşim. | |
PH12020550815A1 (en) | Delayed release deferiprone tablets and methods of using the same | |
MX2018012618A (es) | Composiciones farmaceuticas orales de mesalazina. | |
IN2014MN02245A (tr) | ||
MX2020002078A (es) | Composiciones de amantadina, preparaciones de estas y métodos de uso. | |
EA202090913A1 (ru) | Композиция таблеток с модифицированным высвобождением, содержащая мирабегрон | |
CY1123185T1 (el) | Παραγωγα ινδολιου | |
TR201821114A2 (tr) | Erdostei̇n i̇çeren efervesan farmasöti̇k bi̇leşi̇m | |
WO2019004980A3 (en) | SOLID ORAL PHARMACEUTICAL COMPOSITIONS OF DABIGATRAN DEXILATE | |
TR201722630A2 (tr) | ||
EA201991286A1 (ru) | Твердая фармацевтическая композиция для перорального применения, содержащая тенофовир и эмтрицитабин | |
CY1119701T1 (el) | Σταθερη φαρμακευτικη συνθεση που περιεχει υδροχλωρικη βαρδεναφιλη | |
EA201991288A1 (ru) | Фармацевтические композиции на основе дабигатрана | |
TR201722323A2 (tr) | Dabi̇gatranin oral farmasöti̇k kompozi̇syonlari | |
EA201890929A1 (ru) | Низкие дозировки композиций дипиридамола для перорального приема и их использование | |
TR201914406A2 (tr) | Sapropteri̇n di̇hi̇droklorür ve en az bi̇r farmasöti̇k eksi̇pi̇yan i̇çeren kati oral farmasöti̇k formülasyonlar |