TR201715516A2 - PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE - Google Patents
PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE Download PDFInfo
- Publication number
- TR201715516A2 TR201715516A2 TR2017/15516A TR201715516A TR201715516A2 TR 201715516 A2 TR201715516 A2 TR 201715516A2 TR 2017/15516 A TR2017/15516 A TR 2017/15516A TR 201715516 A TR201715516 A TR 201715516A TR 201715516 A2 TR201715516 A2 TR 201715516A2
- Authority
- TR
- Turkey
- Prior art keywords
- effect
- biophotostimulation
- electric motor
- led source
- program
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title claims abstract description 19
- 102000009123 Fibrin Human genes 0.000 title claims description 10
- 108010073385 Fibrin Proteins 0.000 title claims description 10
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title claims description 10
- 229950003499 fibrin Drugs 0.000 title claims description 10
- 230000000694 effects Effects 0.000 claims abstract description 23
- 210000004369 blood Anatomy 0.000 claims abstract description 18
- 239000008280 blood Substances 0.000 claims abstract description 18
- 238000005119 centrifugation Methods 0.000 claims description 10
- 238000001816 cooling Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000004886 process control Methods 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 10
- 230000029663 wound healing Effects 0.000 abstract description 7
- 230000035876 healing Effects 0.000 abstract description 5
- 238000011282 treatment Methods 0.000 abstract description 5
- 206010052428 Wound Diseases 0.000 abstract description 3
- 208000027418 Wounds and injury Diseases 0.000 abstract description 3
- 238000003745 diagnosis Methods 0.000 abstract description 2
- 210000004872 soft tissue Anatomy 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 17
- 210000004027 cell Anatomy 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 230000001172 regenerating effect Effects 0.000 description 6
- 230000008929 regeneration Effects 0.000 description 3
- 238000011069 regeneration method Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 2
- 208000030653 Jaw disease Diseases 0.000 description 1
- 208000006389 Peri-Implantitis Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000024693 gingival disease Diseases 0.000 description 1
- 201000005562 gingival recession Diseases 0.000 description 1
- 238000002647 laser therapy Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000000258 photobiological effect Effects 0.000 description 1
- 210000004623 platelet-rich plasma Anatomy 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000002278 reconstructive surgery Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B15/00—Other accessories for centrifuges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B15/00—Other accessories for centrifuges
- B04B15/02—Other accessories for centrifuges for cooling, heating, or heat insulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
Landscapes
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Buluş; tıp, diş hekimliği ve veterinerliğin tüm alanlarında, tanı, sert ve yumuşak doku iyileşmesinde, açık ve kapalı yaraların tedavilerinde ve yara iyileşmesinin hızlandırılmasında kullanılan bireyin kendi kanından elde edilen büyüme faktörlerinin sağlanmasında kullanılan fotobiyostimülasyon etkisine sahip santrifüj cihazı ile ilgilidir.Meet; It is related to the centrifuge device with photobiostimulation effect used in all fields of medicine, dentistry and veterinary medicine, used in diagnosis, hard and soft tissue healing, treatment of open and closed wounds, and providing growth factors obtained from the individual's own blood to accelerate wound healing.
Description
TEKNIK ALAN Bulus; tip, dis hekimligi ve veterinerligin tüm alanlarinda, tani, sert ve yumusak doku iyilesmesinde, açik ve kapali yaralarin tedavilerinde ve yara iyilesmesinin hizlandirilmasinda kullanilan bireyin kendi kanindan elde edilen büyüme faktörlerinin saglanmasinda kullanilan fotobiyostimülasyon etkisine sahip santrifüj cihazi ile ilgilidir. ÖNCEKI TEKNIK Rejeneratif tip ve dis hekimligi, günümüz tedavilerinin en büyük hedeflerinden biridir. Kayip ya da hasarli doku parçalarini yeniden olusturabilme istegi ve ihtiyaci, modern tibbin en çok arastirilan tedavi yöntemlerindendir. En iyi doku stimülasyonu, rejenerasyonu tetikleyen otolog GF'Ierden (Growth Factor: Büyüme Faktörleri) elde edilmistir. Bu amaçla, birçok ürün ve teknik kullanilmistir (Örnegin PRP, PDGF, PRF ve CGF gibi). Simdiye kadar büyüme faktörlerinin hazirlanmasi ve konsantrasyonu için çok farkli sistemler gelistirilmistir; bunlar su sekilde Iistelenebilir: 0 Mevcut teknolojiler: o Fibrin Yapistirici (1970) o Platelet konsantrasyonu (cPRP,1998) o Platelet Zengin Plazma (PRP, 1998) o Platelet Zengin Büyüme Faktörleri (PRGF,1998) o Platelet Zengin Fibrin (PRF,2001) o Konsantre Büyüme Faktörleri (Concentrated Growth Factors-CGF- 2006) o Lökosit ve Platelet Zengin Fibrin (L-PRF,2006) 0 Ileri Platelet Zengin Fibrin (A-PRF,2012) o Enjekte edilebilir Platelet Zengin Fibrin (i-PRF,2013) Fakat bu sistemlerin hiçbirinin uygun biyostimülasyon için tam olarak basarili oldugu kanitlanmamistir. Bunun sebebi, yukarida bahsedilen tekniklerin hiçbirinin kanin bütünündeki rejeneratif potansiyeli kullanamamasidir. TECHNICAL FIELD Meet; in all fields of medicine, dentistry and veterinary medicine, diagnosis, hard and soft tissue healing, treatment of open and closed wounds and wound healing growth factors obtained from the individual's own blood used to accelerate It is related to the centrifuge device with photobiostimulation effect used to provide PRIOR ART Regenerative medicine and dentistry is one of the biggest goals of today's treatments. is one. Desire and need to regenerate lost or damaged tissue pieces, It is one of the most researched treatment methods in modern medicine. best tissue stimulation, obtained from autologous GFs (Growth Factors) that trigger regeneration has been made. For this purpose, many products and techniques have been used (For example, PRP, PDGF, PRF) and CGF). For the preparation and concentration of growth factors so far many different systems have been developed; These can be ordered as: 0 Available technologies: o Fibrin Sealer (1970) o Platelet concentration (cPRP,1998) o Platelet Rich Plasma (PRP, 1998) o Platelet Rich Growth Factors (PRGF,1998) o Platelet Rich Fibrin (PRF,2001) o Concentrated Growth Factors (CGF- 2006) o Leukocyte and Platelet Rich Fibrin (L-PRF,2006) 0 Advanced Platelet Rich Fibrin (A-PRF,2012) o Injectable Platelet Rich Fibrin (i-PRF,2013) However, none of these systems is fully successful for appropriate biostimulation. not proven. This is because none of the techniques mentioned above the inability to use the regenerative potential in the whole.
Tip ve dis hekimliginde rejenerasyon için ilgili hücrelerin ya da dokularin biyostimulasyonunu saglatilmasi amaciyla kullanilan diger bir yöntem ise fotobiyositümülasyon yöntemidir. Foto biyositümülasyon olarak da adlandirilan düsük doz lazer tedavisi, miliwattlar seviyesinde lazer isininin canli dokuya uygulanmasi prensibine dayanan, uygulanan bölgede yara iyilesmesini hizlandiran fotobiyolojik bir yöntemdir. Relevant cells or tissues for regeneration in medicine and dentistry Another method used to provide biostimulation is It is a photobiostimulation method. low, also called photobiostimulation dose laser therapy, application of milliwatt-level laser light to living tissue It is a photobiological method based on the principle of accelerating wound healing in the applied area. method.
Rejeneratif teknikler tip alaninda, yara iyilesmesinin hizlandirilmasi, estetik ve rekonstrüktif cerrahi, yaslanmanin etkilerinin geciktirilmesi ve azaltilmasi, saç ekimi, dermatoloji, ortopedi; dis hekimligi alaninda, diseti hastaliklari ve cerrahisi, agiz çene hastaliklari ve cerrahisi, diseti çekilmelerinin kapatilmasi, periimplantitis tedavisi, yara iyilesmesinin hizlandirilmasi ve iyilestirilmesi gibi birçok alanda kullanilmaktadir. In the field of medicine, regenerative techniques are used to accelerate wound healing, aesthetics and reconstructive surgery, delaying and reducing the effects of aging, hair transplantation, dermatology, orthopedics; in dentistry, gum diseases and surgery, oral jaw diseases and surgery, closure of gingival recessions, treatment of periimplantitis, It is used in many areas such as acceleration and healing of wound healing.
BULUSUN KISA AÇIKLAMASI Son yillarda Tip ve dis hekimligi alaninda bireyin kendi kanindan elde edilen büyüme faktörlerinin rejenerasyon amaçli kullanimi popüler hale gelmistir. Ancak günümüzde kullanilan tekniklerin etkinligi kanin içerisindeki bütün rejeneratif potansiyelin kullanilamamasina bagli olarak sinirlidir. Bulus ile konvansiyonel tekniklere fotobiyostimülasyon etkisine sahip LED isik uygulamasi eklenerek kanin içerisindeki rejeneratif potansiyeli ortaya çikarilmaktadir. BRIEF DESCRIPTION OF THE INVENTION In recent years, in the field of medicine and dentistry, obtained from the individual's own blood The use of growth factors for regeneration has become popular. However The effectiveness of the techniques used today is effective in all regenerative limited due to unavailability of potential. conventional with the invention by adding LED light application with photobiostimulation effect to the techniques its regenerative potential is revealed.
Bulus, yumusak ve sert doku yara iyilesmesinin hizinin ve kalitesinin arttirilmasi için kanin sekilli elemanlarinin ayrilmasi, çesitli trombosit konsantrasyonlarinin ve büyüme faktörlerinin elde edilmesi için kan dolu tüpün çesitli süre, hiz ve açilarda santrifüj edilmesi ve biyostimulasyon için gerekli uygun dalga boylarinda LED uygulamasi ve hücrelerin yasamalari için gerekli sicakligin saglanmasini mümkün hale getiren santrifüj cihazi ilgilidir. The invention is to increase the speed and quality of soft and hard tissue wound healing. separation of the shaped elements of the blood for various platelet concentrations and The blood-filled tube can be used at various times, speeds and angles to obtain growth factors. LEDs of appropriate wavelengths required for centrifugation and biostimulation and making it possible to provide the necessary temperature for the cells to live. centrifuge device is related.
SEKILLERIN LISTESI Sekil 1. Fotobiyostimülasyon Destekli Trombositten Zengin Fibrin Ve Konsantre Büyüme Faktörü Santrifüj Cihazi Üstten Görünüm Sekil 2. Santrifüj Selesi ve Santrifüj Tüpleri Sekillerde verilen numaralandirmalara karsilik gelen parçalar: 1. LED kaynagi 3. Mikroislemci 4. Santrifüj Selesi . Infrared Isitici 6. Sogutucu 7. Kabin BULUSUN DETAYLI AÇIKLAMASI Hastanin kendi kanindan büyüme faktörlerinin elde edilmesi ve uygun dalga boylarindaki LED isik ile fotobiyomodülasyonunun hücre proliferasyonunu uyarma ve yara iyilesmesini hizlandirmasi islemleri ayri ayri tip ve dis hekimliginin birçok alaninda kullanilmaktadir. Yumusak ve sert doku üzerine pozitif etkisi bulunan bu iki teknigin birlestirilmesi ile yeni ve özgün bir cihaz olusturularak daha yüksek fayda saglanmaktadir. LIST OF FIGURES Figure 1. Photobiostimulation Supported Platelet-Rich Fibrin and Concentrated Growth Factor Centrifuge Top View Figure 2. Centrifuge Saddle and Centrifuge Tubes Parts corresponding to the numbers given in the figures: 1. LED source 3. Microprocessor 4. Centrifuge Saddle . Infrared Heater 6. Cooler 7. Cabin DETAILED DESCRIPTION OF THE INVENTION Obtaining growth factors from the patient's own blood and using the appropriate wave Stimulating cell proliferation and photobiomodulation with LED light wound healing processes are used separately in many fields of medicine and dentistry. is used. These two techniques, which have a positive effect on soft and hard tissue, higher benefit by creating a new and original device by combining is provided.
Bireyin yara bölgesine, lyllesmeyi hizlandirmak ve iyilesme kalitesini arttirmak için kendi kani alinarak çesitli süre, hiz ve açilarda santrifüj edilerek, çesitli konsantrasyonlarda büyüme faktörleri elde edilmektedir. Sadece merkez kaç kuvvetine dayanan santrifüj islemleri ile sinirli sayida büyüme faktörü elde edilmektedir. Santrifüj islemleri sirasinda (yaklasik 1-30 dakika) kan tüpüne cihazin sahip oldugu uygun dalga boylarinda fotobiyostimülasyon etkisine sahip LED uygulamasi ile büyüme faktörü sayisi arttirilmakta ve hücrelerin yasama süreleri uzatilmaktadir. Santrifüj islemleri sirasinda kan vücudun disarisinda islem görmektedir. Cihazin sahip oldugu isitici ve sogutucular ile uygun sicaklik olusturulup hücreler için uygun ortam saglanmaktadir. To accelerate healing and improve healing quality to the wound area of the individual. By taking their own blood, centrifuging at various times, speeds and angles, various concentrations of growth factors. just the center A limited number of growth factors can be obtained by centrifugation processes based on force is being done. During centrifugation (approximately 1-30 minutes), the blood tube of the device LED with photobiostimulation effect at suitable wavelengths With its application, the number of growth factors is increased and the life span of the cells is increased. is being extended. During centrifugation processes, blood is processed outside of the body. sees. Proper temperature is created with the heaters and coolers of the device. A suitable environment is provided for the cells.
Kan dolu tüpün çesitli süre, hiz ve açilarda santrifüjünü saglayan motoru kontrol eden (kablosuz veri aktarimina da olanak saglayarak bilgisayar, tablet ve cep telefonlari ile de baglanti kurabilen) mikroislemciye sahip cihaz, santrifüj sirasinda çesitli dalga boylarinda biyofotostimülasyon etkisine sahip LED isinlar uygulayarak büyüme faktörlerinin çogaltilmasini ve hücrelerin yasama sürelerini uzatmaktadir. It controls the motor that provides the centrifugation of the blood-filled tube at various times, speeds and angles. computer, tablet and mobile phone (by enabling wireless data transfer) The device, which has a microprocessor (which can also connect with mobile phones) By applying LED beams with biophotostimulation effect of various wavelengths It prolongs the proliferation of growth factors and the life span of cells.
Bulus ile CGF (Konsantre Büyüme Faktörleri) ve Platelet Zengin Fibrin (PRF) teknigine ilave olarak biyofotomodülasyon etkisine sahip uygun dalga boyundaki LED isik kullanilarak kanin içerisindeki rejeneratif potansiyelin artirilmasi ile ilgili hücre ve dokularin biyostimulasyonu saglanir. Fotobiyostimülasyon etkisine sahip, Konsantre Büyüme Faktörleri (CGF) ve Platelet Zengin Fibrin (PRF) yapiminda kullanilmak üzere yapilandirilmis santrifüj; biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynagi (1), Dis rotorlu elektrik motoru (2), dis rotorlu elektrik motorunun (2) ve LED kaynaginin (1) kontrolünü saglayan, kablosuz veri aktarimina ve kablosuz kontrole de izin verebilen mikro islemci (3) ve yazilimi içeren motor sürücü devresi, en az bir adet kan tüpünün yerlestirebilmesi için gerekli açilari ayarlanabilen ve açisi sabitlenebilen santrifüj selesi (4), kabin içi isitmasini saglayan infrared isitici (5), kabin içi sogutmasini saglayan sogutucu (6), ortam sicakligini kontrol eden isi sensörü, fotobiyostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynaginin yerlestirilebilecegi kabin (7), program bilgilerini gösteren dokunmatik gösterge paneli ve islem kontrolünü saglayan kontrol paneli parçalariyla karakterizedir. CGF (Concentrated Growth Factors) and Platelet Rich Fibrin (PRF) by Invention In addition to the technique, LED of the appropriate wavelength with the effect of biophotomodulation cells and cells related to increasing the regenerative potential in the blood using light. biostimulation of tissues is provided. Concentrated, with photobiostimulation effect To be used in the production of Growth Factors (CGF) and Platelet Rich Fibrin (PRF) structured centrifuge; at suitable wavelengths with a biophotostimulating effect Light applying LED source (1), Outer rotor electric motor (2), Outer rotor electric wireless data transmission, which enables the control of the motor (2) and the LED source (1) motor driver including microprocessor (3) and software that can also allow wireless control circuit, the necessary angles can be adjusted for at least one blood tube to be placed. and centrifugal saddle (4) whose angle can be fixed, infrared heater that provides heating inside the cabin (5), the cooler that provides the cabin interior cooling (6), the heat sink that controls the ambient temperature sensor, which applies light at appropriate wavelengths with the effect of photobiostimulation. Cabinet (7) where LED source can be placed, touch screen displaying program information It is characterized by instrument panel and control panel parts that provide process control.
LED kaynagi (1), biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan parçadir. Düsük doz (low-level) diode lazer özelliginde ve 100-2000 nm dalga boyuna sahip biyositümülasyon amaciyla ve mikroislemci tarafindan uygulama süresi ve gücünün kontrol edilmesi amaciyla kullanilmaktadir. LED source (1), light of suitable wavelengths with the effect of biophotostimulation implementing part. It has low-level (low-level) diode laser and 100-2000 nm wavelength for biostimulation and application by microprocessor It is used to control its duration and power.
Dis rotorlu elektrik motoru (2), saat yönünde ve saat yönünün tersine, kullanicinin seçtigi programa ve protokole göre 10-10000 devir/dakika arasinda belirlenen hizlarda ve sürede dönebilmektedir. Parçanin kontrolü mikro islemci ile saglanmaktadir. Dis rotor electric motor (2), clockwise and counterclockwise, Between 10-10000 rpm according to the program and protocol chosen by the user. can return at specified speeds and times. Part control with microprocessor is provided.
Mikro islemci (3), dis rotorlu elektrik motorunun (2) ve LED kaynaginin (1) kontrolünü saglamaktadir. Kablosuz veri aktarimina ve kablosuz kontrole de izin verebilen, kullanicinin seçtigi program ve protokole göre elektrik motorunun dönüs hizi, süresi ve açisini ayarlayan, biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynaginin (1) uygulama süresi (1-60 dakika) ve gücünü belirleyen, kabin (7) içerisindeki sicakligi santrifüj islemi sirasinda ve bekleme süresi boyunca seçilen dereceye ulastiran ve sabit tutmak için isitici ve sogutuculari kontrol eden parçadir. Dis rotorlu elektrik motorunun (2) ve LED kaynaginin (1) kontrolünü saglayan mikro islemcinin (3) barindirdigi yazilim, kablosuz veri aktarimina ve kablosuz kontrole de izin verebilen (bilgisayar, tablet ve cep telefonlari ile de baglanti kurabilen), kullanicinin seçtigi program ve protokole göre elektrik motorunun dönüs hizi, süresi ve açisini ayarlayan, biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynaginin uygulama süresi ve gücünü belirleyen, santrifüj islemi sirasinda ve bekleme süresi boyunca uygun sicaklik kosullarini saglayan, kabin (7) içerisindeki sicakligi seçilen dereceye ulastiran ve sabit tutmak için isitici ve sogutuculari kontrol eden ayrica hasta bilgilerinin saklanmasini da saglamaktadir. Microprocessor (3), outer rotor electric motor (2) and LED source (1) provides control. Allows wireless data transfer and wireless control as well. the rotation of the electric motor according to the program and protocol selected by the user. Suitable wave with biophotostimulation effect, adjusting the speed, duration and angle the application time (1-60 minutes) of the LED source (1) that applies light in lengths and The temperature inside the cabinet (7), which determines its power, is during the centrifugation process and heaters and coolers to reach the selected degree and keep it constant throughout its duration. is the controlling part. The outer rotor electric motor (2) and the LED source (1) The software hosted by the microprocessor (3) that provides the control of and wireless control (also with computers, tablets and mobile phones) connection), according to the program and protocol selected by the user. Appropriate wave with biophotostimulation effect that adjusts rotation speed, duration and angle Determining the application time and power of the LED source, which applies light in lengths, suitable temperature conditions during the centrifugation process and during the waiting period. providing the temperature inside the cabin (7) to the selected degree and keeping it constant. Controlling the heaters and coolers also includes the storage of patient information. it provides.
Motor sürücü devresi, kullanicinin belirleyecegi program ve protokole göre; devir, hiz, süre ve açida dis rotorlu elektrik motorunun (2) istenilen yönde dönmesini saglamakta ve mikroislemci (3) tarafindan kontrol edilmektedir. Motor driver circuit, according to the program and protocol to be determined by the user; rotation of the electric motor (2) with outer rotor in the desired direction in terms of revolution, speed, time and angle. and is controlled by the microprocessor (3).
Santrifüj selesi (4), dis rotorlu elektrik motorunun (2) dis rotor kismina dogrudan sabitlenen ve birlikte hareket eden, açilari ayarlanabilen veya sabit açili en az bir adet kan tüpünün yerlestirilmesine imkan saglayan yapidadir. Ayni zamanda santrifüj selesinin (1) içerisine biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynaklari yerlestirilerek dogrudan kan dolu deney tüpüne biyofotostimülasyon uygulanabilmesine olanak saglar. The centrifuge seat (4) is directly attached to the outer rotor part of the outer rotor electric motor (2). at least one fixed and movable, adjustable angle or fixed angle It has a structure that allows the blood tube to be placed. At the same time centrifuge suitable wavelengths of light with a biophotostimulation effect inside the bin (1) directly into the blood-filled test tube by placing LED sources allows the application of biophotostimulation.
Kabin içi isitmasini saglayan infrared isitici (5); islem öncesi, islem sirasi ve bekleme döneminde, tüpün içerisinde bulundugu kabini (7) ve tüpü, kullanicinin belirleyecegi program ve protokole göre mikroislemci (3) kontrolünde belirlenen sicaklik seviyesine göre isitmaktadir. Infrared heater (5) providing cabin heating; before processing, during processing and During the waiting period, the cabinet (7) and the tube in which the tube is located, must be kept by the user. determined under the control of the microprocessor (3) according to the program and protocol to be determined. It heats according to the temperature level.
Kabin içi sogutmasini saglayan sogutucu (6); islem öncesi, islem sirasi ve bekleme döneminde, tüpün içerisinde bulundugu kabini (7) ve tüpü, kullanicinin belirleyecegi program ve protokole göre mikro islemci kontrolünde belirlenen sicaklik Ortam sicakligini kontrol eden isi sensörü, islem öncesi, islem sirasi ve bekleme döneminde, tüpün içerisinde bulundugu kabini (7) ve tüpü, kullanicinin belirleyecegi program ve protokole göre mikro islemci kontrolünde belirlenen sicaklik seviyesini ayarlamaktadir. Ölçülen sicakligin, istenen sicakligin altinda veya üstünde olmasi durumunda, mikroislemciye (3) gerekli komutu göndererek, sicakligin istenilen seviyeye çekilmesini saglamaktadir. The cooler (6), which provides cooling inside the cabin; before processing, during processing and During the waiting period, the cabinet (7) and the tube in which the tube is located, must be kept by the user. The temperature determined by the microprocessor control according to the program and protocol to be determined. Temperature sensor controlling the ambient temperature, pre-process, in-process and standby period, the cabinet (7) and the tube in which the tube is located, to be determined by the user. the temperature level determined by the microprocessor control according to the program and protocol. is setting. The measured temperature is above or below the desired temperature. In this case, by sending the necessary command to the microprocessor (3), the desired temperature is set. enables it to level up.
Biyofotostimülasyon etkisine sahip uygun dalga boylarinda isik uygulayan LED kaynaginin (1) yerlestirilebilecegi kabin (7), kan tüpünün üzerine, santrifüj islemi öncesi, islem sirasinda ve bekleme döneminde, biyofotostimülasyon etkisine sahip LED kaynaginin (1) uygulanabilmesi için, gerekli sayida ve açida, biyofotostimülasyon etkisine sahip LED kaynaginin (1) yerlestirilmesine olanak saglayan yapidir. Kabinin (7) tabaninda, üst kapak kisminda ve iç yan duvarlarinda LED kaynaginin yerlestirilecegi yuvalar bulunmaktadir. LED applying light at appropriate wavelengths with a biophotostimulation effect The cabinet (7), where the source (1) can be placed, is placed on the blood tube for centrifugation. It has a biophotostimulation effect before, during the procedure and during the waiting period. In order for the LED source (1) to be applied, biophotostimulation must be performed at the required number and angle. It is the structure that allows the LED source (1) to be placed, which has an effect. of the cabin (7) on the base, top cover and inner side walls of the LED source. There are slots for it to be placed.
Dokunmatik gösterge paneli, kabin (7) üzerinde bulunan ve program bilgilerini gösteren parçadir. Islem öncesinde, islem sirasinda ve bekleme döneminde ortamin isinini ve islem bilgilerini kullaniciya görsel olarak aktarmaktadir. Gösterge paneli ile birlikte kabin (7) üzerinde yer alan ve islem kontrolünü saglayan kontrol paneli, kullanicinin seçtigi program ve protokole göre mikroislemciye komut göndererek santrifüj ve biyostimülasyon islemlerinin tercihlerinin yapilmasini ve kullanici tarafindan kontrol edilmesini saglamaktadir. The touch screen panel displays program information on the cabinet (7). showing piece. Before the transaction, during the operation and during the waiting period, the environment It visually conveys the job and transaction information to the user. with instrument panel The control panel, which is located on the cabin (7) and provides process control, by sending commands to the microprocessor according to the program and protocol selected by the user. centrifugation and biostimulation processes to be preferred and the user is controlled by.
Claims (1)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/15516A TR201715516A2 (en) | 2017-10-12 | 2017-10-12 | PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE |
| PCT/TR2018/050133 WO2019074455A2 (en) | 2017-10-12 | 2018-04-02 | The centrifuge device for platelet-rich fibrin and concentrated growth factor with photobiostimulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/15516A TR201715516A2 (en) | 2017-10-12 | 2017-10-12 | PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201715516A2 true TR201715516A2 (en) | 2017-11-21 |
Family
ID=66100975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2017/15516A TR201715516A2 (en) | 2017-10-12 | 2017-10-12 | PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE |
Country Status (2)
| Country | Link |
|---|---|
| TR (1) | TR201715516A2 (en) |
| WO (1) | WO2019074455A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112410209A (en) * | 2020-11-26 | 2021-02-26 | 广州达晖生物技术股份有限公司 | Temperature control system for chromosome harvesting equipment and automatic temperature control method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7671975B2 (en) * | 2004-07-01 | 2010-03-02 | Caridianbct, Inc. | Blood processing apparatus with dedicated stroboscopic controller for LED source |
| US20130344560A1 (en) * | 2007-04-30 | 2013-12-26 | Jon Weston | Method for localized photo-irradiation of biological tissues to stimulate tissue regeneration or repair |
| CN103635209A (en) * | 2011-09-26 | 2014-03-12 | 汾沃有限公司 | Optical monitoring system for blood processing system |
| WO2014126545A1 (en) * | 2013-02-18 | 2014-08-21 | Akman Serhan | A centrifuge structured for use in making platelet-rich fibrin |
-
2017
- 2017-10-12 TR TR2017/15516A patent/TR201715516A2/en unknown
-
2018
- 2018-04-02 WO PCT/TR2018/050133 patent/WO2019074455A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019074455A3 (en) | 2019-08-08 |
| WO2019074455A2 (en) | 2019-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Singh et al. | In situ bioprinting–bioprinting from benchside to bedside? | |
| JP6871156B2 (en) | Injection device | |
| JP7053637B2 (en) | Automatic disinfectant and method for disinfecting skin | |
| Geminiani et al. | Temperature change during non-contact diode laser irradiation of implant surfaces | |
| JP2020505164A (en) | Apparatus and corresponding method for identifying and manipulating blood vessels | |
| CN104288914B (en) | Intelligent laser therapy apparatus for treating onychomycosis | |
| Fornaini et al. | Different laser wavelengths comparison in the second-stage implant surgery: an ex vivo study | |
| Macri et al. | CO 2 laser as auxiliary in the debonding of ceramic brackets | |
| TR201715516A2 (en) | PHOTOBIOSTIMULATION SUPPORTED THROMBOSITE RICH FIBRIN AND CONCENTRATED GROWTH FACTOR CENTRIFUGAL DEVICE | |
| Gorler et al. | The effects of Er: YAG, Nd: YAG, and Ho: YAG laser surface treatments to acrylic resin denture bases on the tensile bond strength of silicone-based resilient liners | |
| Chung et al. | Photobiostimulation as a modality to accelerate orthodontic tooth movement | |
| Yilanci et al. | Intrapulpal temperature increase during Er: YAG laser-aided debonding of ceramic brackets | |
| WO2017016085A1 (en) | Single x-ray source blood irradiation device and irradiation method thereof | |
| CN111714202A (en) | Tumor ablation monitoring assembly, device and system | |
| CN106621068A (en) | Semiconductor laser module and method for noninvasive medical treatment | |
| Takebe et al. | Effect of low intensity pulsed ultrasound stimulation on sinus augmentation in rabbits | |
| CN103933671A (en) | Precision photodynamic therapy system | |
| US20220256839A1 (en) | Vessel treatment systems, methods, and kits | |
| Lu et al. | Effectiveness of concentrated growth factor and laser therapy on wound healing, inferior alveolar nerve injury and periodontal bone defects post‐mandibular impacted wisdom tooth extraction: A randomized clinical trial | |
| Zheng et al. | High-rhythm automatic driver for bone traction: an experimental study in rabbits | |
| Gecgelen Cesur et al. | Evaluation of perceived pain during the first week of rapid maxillary expansion treatment | |
| JP6213964B2 (en) | Method and apparatus for producing low-degradable fibrin gel membrane for regenerative treatment | |
| Kubicek et al. | Optimization of Laser Therapy Parameters in Dependence of Spot Size | |
| Arany | Special issue on stem cells and photobiomodulation therapy | |
| CN104042343B (en) | A kind of multi-wave band laser synthetic therapeutic apparatus |