TR200607443T2 - Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation - Google Patents

Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation

Info

Publication number
TR200607443T2
TR200607443T2 TR2006/07443T TR200607443T TR200607443T2 TR 200607443 T2 TR200607443 T2 TR 200607443T2 TR 2006/07443 T TR2006/07443 T TR 2006/07443T TR 200607443 T TR200607443 T TR 200607443T TR 200607443 T2 TR200607443 T2 TR 200607443T2
Authority
TR
Turkey
Prior art keywords
mct
membrane
nucleic acid
acid molecules
proteins
Prior art date
Application number
TR2006/07443T
Other languages
Turkish (tr)
Other versions
TR200607443T1 (en
Inventor
Pompejus Markus
Kröger Burkhard
Haberhauer Gregor
Zelder Oskar
Schröder Hartwig
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200607443T1 publication Critical patent/TR200607443T1/en
Publication of TR200607443T2 publication Critical patent/TR200607443T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Corynebacterium glutamicum'dan türetilmiş yeni MCT proteinlerini şifreleyen MCT nükleik asit molekülleri adlı izole edilmiş nükleik asit molekülleri tarif edilmektedir. Buluş anti duyarlı nükleik asit molekülleri, MCT nükleik asit molekülleri ihtiva eden yemden birleştirici tanım vektörleri ve tanım vektörlerinin yerleştirildiği konakçı hücreler de sağlar. Hali hazırda buluş ayrıca izole edilmiş MCT proteinleri, mutasyon geçirmiş MCT proteinleri, füzyon proteinleri, antijenik peptitler ve bu organizmadaki MCT genlerinin genetik mühendisliğine dayanarak arzu edilen bir bileşiğin C. Glutamicum'dan üretiminin geliştirilmesine yönelik metotlar sağlar.Isolated nucleic acid molecules called MCT nucleic acid molecules encoding novel MCT proteins derived from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCT nucleic acid molecules, and host cells into which expression vectors have been introduced. Currently, the invention also provides isolated MCT proteins, mutated MCT proteins, fusion proteins, antigenic peptides, and methods for improving the production of a desired compound from C. glutamicum based on genetic engineering of MCT genes in this organism.

TR2006/07443T 1999-06-25 2000-06-23 Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation TR200607443T2 (en)

Applications Claiming Priority (35)

Application Number Priority Date Filing Date Title
US14103199P 1999-06-25 1999-06-25
DE19931563 1999-07-08
DE19931454 1999-07-08
DE19931478 1999-07-08
DE19932227 1999-07-09
DE19932212 1999-07-09
DE19932122 1999-07-09
DE19932229 1999-07-09
DE19932190 1999-07-09
DE19932128 1999-07-09
DE19932124 1999-07-09
DE19932209 1999-07-09
DE19932182 1999-07-09
DE19932191 1999-07-09
DE19932230 1999-07-09
DE19932228 1999-07-09
DE19932125 1999-07-09
DE19932180 1999-07-09
DE19933006 1999-07-14
DE19933005 1999-07-14
DE19932927 1999-07-14
DE19940831 1999-08-27
DE19940766 1999-08-27
DE19940832 1999-08-27
DE19940765 1999-08-27
DE19940833 1999-08-27
DE19940830 1999-08-27
DE19940764 1999-08-27
DE19941379 1999-08-31
DE19941395 1999-08-31
DE19941378 1999-08-31
DE19942088 1999-09-03
DE19942078 1999-09-03
DE19942079 1999-09-03
DE19942077 1999-09-03

Publications (2)

Publication Number Publication Date
TR200607443T1 TR200607443T1 (en) 2007-04-24
TR200607443T2 true TR200607443T2 (en) 2007-10-22

Family

ID=27586932

Family Applications (4)

Application Number Title Priority Date Filing Date
TR2006/07443T TR200607443T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation
TR2006/07441T TR200607441T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation.
TR2001/03708T TR200103708T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant
TR2006/07442T TR200607442T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation.

Family Applications After (3)

Application Number Title Priority Date Filing Date
TR2006/07441T TR200607441T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation.
TR2001/03708T TR200103708T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant
TR2006/07442T TR200607442T2 (en) 1999-06-25 2000-06-23 Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation.

Country Status (10)

Country Link
EP (1) EP1255839A2 (en)
JP (2) JP2004513603A (en)
KR (3) KR100878332B1 (en)
CA (1) CA2380863A1 (en)
CZ (1) CZ20014660A3 (en)
ES (1) ES2177476T1 (en)
MX (1) MXPA01012845A (en)
SK (1) SK18912001A3 (en)
TR (4) TR200607443T2 (en)
WO (1) WO2001000805A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU781091B2 (en) 1999-07-02 2005-05-05 Ajinomoto Co., Inc. DNA encoding sucrose PTS enzyme II
DE19941478A1 (en) * 1999-09-01 2001-03-08 Degussa New nucleotide sequences coding for the thrE gene and process for the fermentative production of L-threonine with coryneform bacteria
DE10021829A1 (en) * 2000-05-04 2001-11-08 Degussa New nucleotide sequences coding for the pgsA2 gene
US6562607B2 (en) 2000-05-04 2003-05-13 Degussa-Huls Aktiengesellschaft Nucleotide sequences coding for the cls gene
DE10021828A1 (en) * 2000-05-04 2001-11-08 Degussa New nucleotide sequences coding for the cdsA gene
DE10021831A1 (en) * 2000-05-04 2001-11-08 Degussa New nucleotide sequences coding for the fadD15 gene
DE10021832A1 (en) * 2000-05-04 2001-11-08 Degussa New nucleotide sequences coding for the cma gene
DE10021826A1 (en) * 2000-05-04 2001-11-08 Degussa New mutant coryneform bacterium, useful for production of amino acids, especially glutamate, has increased activity of cardiolipin synthase
DE10023400A1 (en) 2000-05-12 2001-11-15 Degussa New acyl-carrier protein gene, acp, from coryneform bacteria, useful for increasing fermentative production of amino acids, especially lysine
US20020081673A1 (en) 2000-06-02 2002-06-27 Bettina Mockel Novel nucleotide sequences coding for the glbO gene
DE10032173A1 (en) 2000-07-01 2002-01-17 Degussa New nucleotide sequences encoding the plsC gene
DE10045579A1 (en) * 2000-09-15 2002-04-11 Degussa New nucleotide sequences coding for the atr61 gene
AU2001293731A1 (en) * 2000-09-19 2002-04-02 Degussa A.G. Nucleotide sequences coding for the dcta gene
DE10057801A1 (en) * 2000-11-22 2002-05-23 Degussa New polynucleotide encoding the CysQ transporter of coryneform bacteria, useful, when over expressed, for increasing fermentative production of amino acids
DE10154179A1 (en) * 2001-11-05 2003-05-08 Basf Ag Genes coding for membrane synthesis and membrane transport proteins
DE10154270A1 (en) 2001-11-05 2003-05-15 Basf Ag Genes that code for carbon metabolism and energy production proteins
DE10163167A1 (en) * 2001-12-21 2003-07-03 Degussa Process for the fermentative production of L-amino acids and use of coryneform bacteria
ATE473284T1 (en) * 2002-05-14 2010-07-15 Martek Biosciences Corp CAROTINE SYNTHASE GENE AND ITS USE
US7468262B2 (en) 2003-05-16 2008-12-23 Ajinomoto Co., Inc. Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
DE102004009454A1 (en) * 2004-02-27 2005-09-15 Degussa Ag Fermentative production of L-amino acids, especially methionine, useful e.g. in animal nutrition, by culturing bacteria in which components of the methionine uptake system are suppressed
EP2149607B1 (en) * 2007-04-10 2017-12-20 Ajinomoto Co., Inc. Method for production of succinic acid
KR101694850B1 (en) * 2014-10-08 2017-01-10 씨제이제일제당 주식회사 Microorganism producing L-glutamine and process for preparing L-glutamine using the same
US10428357B2 (en) * 2017-04-04 2019-10-01 NNB Nutrition USA, LLC Preparation of (R)-3-hydroxybutyric acid or its salts by one-step fermentation
KR101968317B1 (en) 2018-02-23 2019-04-11 씨제이제일제당 주식회사 Novel L-tryptophan export protein and the method of producing L-tryptophan usingthe same
WO2019228937A1 (en) * 2018-05-28 2019-12-05 Universitaet Des Saarlandes Means and methods for the production of glutarate
EP3670525A1 (en) * 2018-12-18 2020-06-24 Evonik Operations GmbH Method for the fermentative production of l-lysine using c. glutamicum strains with a mutated kup transporter
CN112143676B (en) * 2020-09-21 2022-03-18 山西大学 Bacillus halodurans for producing alkaline protease and method and application of bacillus halodurans for producing alkaline protease
CN114763372A (en) * 2021-01-13 2022-07-19 中国科学院天津工业生物技术研究所 Protein with L-proline efflux function and application thereof
KR102261851B1 (en) * 2021-01-15 2021-06-04 씨제이제일제당 (주) Novel ABC transporter ATP-binding protein variant and a method for producing L-lysine using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196453B (en) * 1986-07-04 1988-11-16 Sclavo Spa CORYNEBACTERIUM DIPHTHERIAE DNA ELEMENT WITH TYPICAL PROPERTIES OF AN IS INSERTION ELEMENT
US6649379B1 (en) * 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
JP2967996B2 (en) * 1989-06-06 1999-10-25 協和醗酵工業株式会社 Method for producing L-tryptophan
MY113040A (en) * 1994-02-24 2001-11-30 Ajinomoto Kk Novel gene derived from coryneform bacteria and use thereof
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences

Also Published As

Publication number Publication date
TR200607441T2 (en) 2007-02-21
SK18912001A3 (en) 2002-10-08
TR200607443T1 (en) 2007-04-24
KR20070087032A (en) 2007-08-27
TR200103708T2 (en) 2002-08-21
CZ20014660A3 (en) 2002-09-11
MXPA01012845A (en) 2002-07-09
WO2001000805A2 (en) 2001-01-04
ES2177476T1 (en) 2002-12-16
CA2380863A1 (en) 2001-01-04
KR100878332B1 (en) 2009-01-14
KR20030002295A (en) 2003-01-08
KR20060118626A (en) 2006-11-23
WO2001000805A3 (en) 2001-10-25
JP2004513603A (en) 2004-05-13
EP1255839A2 (en) 2002-11-13
TR200607442T2 (en) 2007-02-21
KR100834989B1 (en) 2008-06-03
JP2006271389A (en) 2006-10-12

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