TR200601379T1 - Rosiglitazon maleat polimorflarının üretilmesine mahsus işlem. - Google Patents
Rosiglitazon maleat polimorflarının üretilmesine mahsus işlem.Info
- Publication number
- TR200601379T1 TR200601379T1 TR2006/01379T TR200601379T TR200601379T1 TR 200601379 T1 TR200601379 T1 TR 200601379T1 TR 2006/01379 T TR2006/01379 T TR 2006/01379T TR 200601379 T TR200601379 T TR 200601379T TR 200601379 T1 TR200601379 T1 TR 200601379T1
- Authority
- TR
- Turkey
- Prior art keywords
- production
- rosiglitazone maleate
- rosiglitazone
- polymorphs
- maleate polymorphs
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229960003271 rosiglitazone maleate Drugs 0.000 title 1
- SUFUKZSWUHZXAV-BTJKTKAUSA-N rosiglitazone maleate Chemical compound [H+].[H+].[O-]C(=O)\C=C/C([O-])=O.C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O SUFUKZSWUHZXAV-BTJKTKAUSA-N 0.000 title 1
- YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 abstract 6
- 229960004586 rosiglitazone Drugs 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Bu buluş, rosiglitazonun hazırlanması için işlemlere, bu işlemler ile hazırlanan rosiglitazona ve rosiglitazonun farmasötik bileşimleri ve bu farmasötik bileşimlerin terapötik kullanımlarına ve bu bileşimler kullanılan tedavi usullerine ilişkindir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0320304A GB2405403A (en) | 2003-08-29 | 2003-08-29 | Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200601379T1 true TR200601379T1 (tr) | 2007-01-22 |
Family
ID=28686590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/01379T TR200601379T1 (tr) | 2003-08-29 | 2004-08-13 | Rosiglitazon maleat polimorflarının üretilmesine mahsus işlem. |
Country Status (9)
Country | Link |
---|---|
US (1) | US7678916B2 (tr) |
KR (1) | KR101145433B1 (tr) |
AU (1) | AU2004268816B2 (tr) |
CA (1) | CA2536784A1 (tr) |
DE (1) | DE112004001572T5 (tr) |
GB (2) | GB2405403A (tr) |
RU (1) | RU2342385C2 (tr) |
TR (1) | TR200601379T1 (tr) |
WO (1) | WO2005021541A2 (tr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020137940A1 (en) | 1997-12-16 | 2002-09-26 | Smithkline Beecham P.L.C. | 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical |
US20040248945A1 (en) | 1999-04-23 | 2004-12-09 | Smithkline Beecham P.L.C. | Thiazolidinedione derivative and its use as antidiabetic |
CZ297266B6 (cs) * | 2004-09-10 | 2006-10-11 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
WO2009104200A1 (en) * | 2008-02-21 | 2009-08-27 | Biocon Limited | A method for preparation of thiazolidinedione derivatives |
EP2184055A1 (en) * | 2008-11-07 | 2010-05-12 | LEK Pharmaceuticals d.d. | Process for preparing solid dosage forms of rosiglitazone maleate |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
WO1997027191A1 (en) * | 1996-06-19 | 1997-07-31 | Dr. Reddy's Research Foundation | Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation |
GB9723295D0 (en) * | 1997-11-04 | 1998-01-07 | Smithkline Beecham Plc | Novel process |
GB9726563D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
GB9726568D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
GB9726566D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
US6602291B1 (en) * | 1999-04-05 | 2003-08-05 | Raymedica, Inc. | Prosthetic spinal disc nucleus having a shape change characteristic |
MXPA01010822A (es) * | 1999-04-23 | 2002-06-04 | Smithkline Beecham Plc | Composicion farmaceutica novedosa. |
DZ3155A1 (fr) * | 1999-04-23 | 2000-11-02 | Smithkline Beecham Plc | Nouvelle composition pharmaceutique. |
CO5170421A1 (es) * | 1999-04-23 | 2002-06-27 | Smithkline Beecham Plc | Nuevo compuesto farmaceutico maleico |
US7060100B2 (en) * | 1999-10-08 | 2006-06-13 | Ferree Bret A | Artificial disc and joint replacements with modular cushioning components |
AU9123201A (en) * | 2000-09-26 | 2002-04-08 | Reddy S Res Foundation | Novel polymorphic forms of 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,4-dione maleate and process for their preparation |
US6733533B1 (en) * | 2002-11-19 | 2004-05-11 | Zimmer Technology, Inc. | Artificial spinal disc |
WO2004062667A1 (en) * | 2003-01-08 | 2004-07-29 | Dr. Reddy's Laboratories Limited | Amorphous form of rosiglitazone maleate and process for preparation thereof |
GB0307259D0 (en) * | 2003-03-28 | 2003-05-07 | Glaxo Group Ltd | Process |
US6893465B2 (en) * | 2003-03-31 | 2005-05-17 | Shi, Tain-Yew | Vividly simulated prosthetic intervertebral disc |
EP1468997A3 (en) * | 2003-04-18 | 2004-11-03 | CHEMI S.p.A. | Polymorphous forms of rosiglitazone maleate |
-
2003
- 2003-08-29 GB GB0320304A patent/GB2405403A/en not_active Withdrawn
-
2004
- 2004-08-13 RU RU2006110040/04A patent/RU2342385C2/ru not_active IP Right Cessation
- 2004-08-13 WO PCT/GB2004/003519 patent/WO2005021541A2/en active Application Filing
- 2004-08-13 GB GB0606312A patent/GB2421504B/en not_active Expired - Fee Related
- 2004-08-13 CA CA002536784A patent/CA2536784A1/en not_active Abandoned
- 2004-08-13 US US10/569,439 patent/US7678916B2/en not_active Expired - Fee Related
- 2004-08-13 DE DE112004001572T patent/DE112004001572T5/de not_active Withdrawn
- 2004-08-13 AU AU2004268816A patent/AU2004268816B2/en not_active Ceased
- 2004-08-13 KR KR1020067004005A patent/KR101145433B1/ko not_active IP Right Cessation
- 2004-08-13 TR TR2006/01379T patent/TR200601379T1/tr unknown
Also Published As
Publication number | Publication date |
---|---|
WO2005021541A2 (en) | 2005-03-10 |
DE112004001572T5 (de) | 2006-07-06 |
AU2004268816A1 (en) | 2005-03-10 |
GB2421504B (en) | 2008-12-03 |
GB2405403A (en) | 2005-03-02 |
GB0606312D0 (en) | 2006-05-10 |
GB0320304D0 (en) | 2003-10-01 |
CA2536784A1 (en) | 2005-03-10 |
KR101145433B1 (ko) | 2012-05-16 |
GB2421504A (en) | 2006-06-28 |
RU2342385C2 (ru) | 2008-12-27 |
US20060264639A1 (en) | 2006-11-23 |
US7678916B2 (en) | 2010-03-16 |
WO2005021541A3 (en) | 2005-05-06 |
AU2004268816B2 (en) | 2011-04-14 |
KR20070027483A (ko) | 2007-03-09 |
RU2006110040A (ru) | 2007-10-10 |
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