TR200301959T1 - Bupropion hidroklorürün hazırlanması için proses - Google Patents

Bupropion hidroklorürün hazırlanması için proses

Info

Publication number
TR200301959T1
TR200301959T1 TR2003/01959T TR200301959T TR200301959T1 TR 200301959 T1 TR200301959 T1 TR 200301959T1 TR 2003/01959 T TR2003/01959 T TR 2003/01959T TR 200301959 T TR200301959 T TR 200301959T TR 200301959 T1 TR200301959 T1 TR 200301959T1
Authority
TR
Turkey
Prior art keywords
preparation
bupropion hydrochloride
bupropion
butylamine
tertiary
Prior art date
Application number
TR2003/01959T
Other languages
English (en)
Inventor
Dabak Kadi̇r
Keski̇n Hülya
Yurdakul Ayci̇l
Ridvanoğlu Nurten
Original Assignee
Bös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A. Ş.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A. Ş. filed Critical Bös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A. Ş.
Publication of TR200301959T1 publication Critical patent/TR200301959T1/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bu bulus, bupropion hidroklorürün hazirlanmasi ile ilgilidir.Bupropion serbest bazi elde edebilmek için 3'-kloropropiofenon' un tersiyer-butilamin varliginda brom ile reaksiyonu ve sonra hidroklorik asit ilavesi ile bupropion hidroklorür' ün elde edilmesi tanimlanmistir. Bulusun temel özelligi tersiyer-butilamin' in solvent ve reaktan olarak kullanilmasidir.
TR2003/01959T 2002-09-10 2002-09-10 Bupropion hidroklorürün hazırlanması için proses TR200301959T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/TR2002/000057 WO2004024674A1 (en) 2002-09-10 2002-09-10 Process for the preparation of bupropion hydrochloride

Publications (1)

Publication Number Publication Date
TR200301959T1 true TR200301959T1 (tr) 2004-10-21

Family

ID=31989676

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2003/01959T TR200301959T1 (tr) 2002-09-10 2002-09-10 Bupropion hidroklorürün hazırlanması için proses

Country Status (3)

Country Link
AU (1) AU2002337634A1 (tr)
TR (1) TR200301959T1 (tr)
WO (1) WO2004024674A1 (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200711123B (en) 2005-06-27 2009-08-26 Biovail Lab Int Srl Modified-release formulations of a bupropion salt
WO2008099418A2 (en) * 2007-02-12 2008-08-21 Alembic Limited An improved process for preparing bupropion hydrochloride
CN100560563C (zh) 2007-07-06 2009-11-18 浙江普洛医药科技有限公司 盐酸安非他酮的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2155194A (en) * 1938-10-27 1939-04-18 Kamlet Jonas Preparation of alpha-alkylaminoacylophenones
BE759838A (fr) * 1969-12-04 1971-06-03 Wellcome Found Cetones a activite biologique
US3885046A (en) * 1969-12-04 1975-05-20 Burroughs Wellcome Co Meta chloro or fluoro substituted alpha-T-butylaminopropionphenones in the treatment of depression

Also Published As

Publication number Publication date
AU2002337634A1 (en) 2004-04-30
WO2004024674A1 (en) 2004-03-25

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