TR200001682T2 - Değiştirilmiş biyolojik tanınma gösteren değiştirilmiş polisakaridler - Google Patents

Değiştirilmiş biyolojik tanınma gösteren değiştirilmiş polisakaridler

Info

Publication number
TR200001682T2
TR200001682T2 TR2000/01682T TR200001682T TR200001682T2 TR 200001682 T2 TR200001682 T2 TR 200001682T2 TR 2000/01682 T TR2000/01682 T TR 2000/01682T TR 200001682 T TR200001682 T TR 200001682T TR 200001682 T2 TR200001682 T2 TR 200001682T2
Authority
TR
Turkey
Prior art keywords
altered biological
modified polysaccharides
biological recognition
polysaccharides
altered
Prior art date
Application number
TR2000/01682T
Other languages
English (en)
Inventor
Bo.E.Hedlund
P. Weber Thomas
R. Dragsten Paul
J. Hanson Gregory
E.Hallaway Ph�L�P
Original Assignee
Biomedical Frontiers, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomedical Frontiers, Inc. filed Critical Biomedical Frontiers, Inc.
Publication of TR200001682T2 publication Critical patent/TR200001682T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/547—Chelates, e.g. Gd-DOTA or Zinc-amino acid chelates; Chelate-forming compounds, e.g. DOTA or ethylenediamine being covalently linked or complexed to the pharmacologically- or therapeutically-active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Bulus polisakaridler, degistirilmis biyolojik özelliklere sahip birlestirilmis polisakaridler ve bu polisakaridler ve birlestirilmis olanlari üretmek için yöntemlerle ilgilidir.
TR2000/01682T 1997-12-09 1998-12-09 Değiştirilmiş biyolojik tanınma gösteren değiştirilmiş polisakaridler TR200001682T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6907997P 1997-12-09 1997-12-09
US6909597P 1997-12-11 1997-12-11

Publications (1)

Publication Number Publication Date
TR200001682T2 true TR200001682T2 (tr) 2001-02-21

Family

ID=26749664

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01682T TR200001682T2 (tr) 1997-12-09 1998-12-09 Değiştirilmiş biyolojik tanınma gösteren değiştirilmiş polisakaridler

Country Status (12)

Country Link
US (1) US6479468B1 (tr)
EP (1) EP1037642B9 (tr)
JP (1) JP4435412B2 (tr)
AT (1) ATE425758T1 (tr)
AU (1) AU761784B2 (tr)
BR (1) BR9813465A (tr)
CA (1) CA2314716C (tr)
DE (1) DE69840673D1 (tr)
DK (1) DK1037642T3 (tr)
ES (1) ES2325005T3 (tr)
TR (1) TR200001682T2 (tr)
WO (1) WO1999029328A1 (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236224A1 (en) * 1997-12-09 2003-12-25 Hedlund Bo E. Modified polysaccharides exhibiting altered biological recognition
US6780852B2 (en) 1997-12-09 2004-08-24 Bo E. Hedlund Modified polysaccharides exhibiting altered biological recognition
AU2001296915A1 (en) 2000-09-26 2002-04-08 Sidney Kimmel Cancer Center Inhibition of antigen presentation with poorly catabolized polymers
EP1707632A1 (de) * 2005-04-01 2006-10-04 Bayer CropScience GmbH Phosphorylierte waxy-Kartoffelstärke
US7709001B2 (en) * 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2779798C (en) 2009-09-30 2019-03-19 Novartis Ag Conjugation of staphylococcus aureus type 5 and type 8 capsular polysaccharides
CN115073625B (zh) 2015-10-26 2024-01-16 哈佛学院院长等 还原和氧化的多糖及其使用方法
WO2018229117A1 (en) * 2017-06-13 2018-12-20 Merz Pharma Gmbh & Co. Kgaa Mixing nozzle, application device, kit and method using the mixing nozzle or application device
CN110868852B (zh) * 2017-07-06 2023-06-02 拜耳股份公司 用于杂草控制的装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB977694A (en) * 1959-12-23 1964-12-09 Chugai Pharmaceutical Co Ltd Starch derivatives
NL270107A (tr) 1960-10-11 1964-07-10
JPS5634701A (en) * 1979-08-29 1981-04-07 Meito Sangyo Kk Beta-1,3-glucan, its preparation and use
US4419365A (en) 1981-12-21 1983-12-06 Ciba-Geigy Corporation Method of treating Alzheimer's disease
US5217998A (en) 1985-07-02 1993-06-08 Biomedical Frontiers, Inc. Composition for the stabilization of deferoxamine to chelate free ions in physiological fluid
US4863964A (en) * 1985-07-02 1989-09-05 Biomedical Frontiers, Inc. Method for the stabilization of deferoxamine to chelate free ions in physiological fluid
US4863961A (en) * 1985-11-25 1989-09-05 G. D. Searle & Co. Tetraenyl prostaglandins
US4987253A (en) 1988-09-19 1991-01-22 University Of Florida Method for the synthesis of desferrioxamine B and analogs thereof
US5268165A (en) 1990-10-16 1993-12-07 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
US5493053A (en) 1994-12-21 1996-02-20 University Of Florida Research Foundation, Inc. Method for preparing desferrioxamine B and homologs thereof
US5811510A (en) * 1995-04-14 1998-09-22 General Hospital Corporation Biodegradable polyacetal polymers and methods for their formation and use
US5847110A (en) 1997-08-15 1998-12-08 Biomedical Frontiers, Inc. Method of reducing a schiff base

Also Published As

Publication number Publication date
DE69840673D1 (de) 2009-04-30
BR9813465A (pt) 2002-01-22
DK1037642T3 (da) 2009-07-06
ES2325005T3 (es) 2009-08-21
JP4435412B2 (ja) 2010-03-17
WO1999029328A1 (en) 1999-06-17
EP1037642A1 (en) 2000-09-27
EP1037642B9 (en) 2010-10-13
CA2314716C (en) 2009-02-03
US6479468B1 (en) 2002-11-12
AU1719799A (en) 1999-06-28
JP2001525369A (ja) 2001-12-11
AU761784B2 (en) 2003-06-12
CA2314716A1 (en) 1999-06-17
EP1037642B1 (en) 2009-03-18
ATE425758T1 (de) 2009-04-15

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