TR199800011T1 - Benzo[g] kuinolin türevleri - Google Patents
Benzo[g] kuinolin türevleriInfo
- Publication number
- TR199800011T1 TR199800011T1 TR1998/00011T TR9800011T TR199800011T1 TR 199800011 T1 TR199800011 T1 TR 199800011T1 TR 1998/00011 T TR1998/00011 T TR 1998/00011T TR 9800011 T TR9800011 T TR 9800011T TR 199800011 T1 TR199800011 T1 TR 199800011T1
- Authority
- TR
- Turkey
- Prior art keywords
- revleri
- benzo
- quinoline
- compounds
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/08—Aza-anthracenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Bulus formül I bilesiklerini saglar. Içerisinde X, Y, R1, R2, R3 ve R4 açiklamada (tarifnamede) tanimlandigi gibidir; ayrica bunlarin hazirlanma yöntemini saglar. Formül I bilesikleri ilaç olarak faydalidir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9513880.6A GB9513880D0 (en) | 1995-07-07 | 1995-07-07 | Organic compounds |
GBGB9603988.8A GB9603988D0 (en) | 1996-02-26 | 1996-02-26 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199800011T1 true TR199800011T1 (tr) | 1998-04-21 |
Family
ID=26307342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1998/00011T TR199800011T1 (tr) | 1995-07-07 | 1996-07-05 | Benzo[g] kuinolin türevleri |
Country Status (28)
Country | Link |
---|---|
US (1) | US5885988A (tr) |
EP (1) | EP0839136B1 (tr) |
JP (1) | JPH11509197A (tr) |
KR (1) | KR19990028757A (tr) |
CN (1) | CN1193964A (tr) |
AR (1) | AR004672A1 (tr) |
AT (1) | ATE201199T1 (tr) |
AU (1) | AU703325B2 (tr) |
BR (1) | BR9609326A (tr) |
CA (1) | CA2224436A1 (tr) |
CO (1) | CO4750662A1 (tr) |
CZ (1) | CZ1698A3 (tr) |
DE (1) | DE69612852T2 (tr) |
DK (1) | DK0839136T3 (tr) |
ES (1) | ES2158327T3 (tr) |
GR (1) | GR3036346T3 (tr) |
HU (1) | HUP9802937A3 (tr) |
IL (1) | IL122854A (tr) |
NO (1) | NO310070B1 (tr) |
NZ (1) | NZ313606A (tr) |
PE (1) | PE1998A1 (tr) |
PL (1) | PL324106A1 (tr) |
PT (1) | PT839136E (tr) |
RU (1) | RU2158738C2 (tr) |
SK (1) | SK1798A3 (tr) |
TR (1) | TR199800011T1 (tr) |
TW (1) | TW357143B (tr) |
WO (1) | WO1997003054A1 (tr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9711043D0 (en) | 1997-05-29 | 1997-07-23 | Ciba Geigy Ag | Organic compounds |
EP1070054A1 (en) * | 1998-04-08 | 2001-01-24 | Takeda Chemical Industries, Ltd. | Amine compounds, their production and their use as somatostatin receptor antagonists or agonists |
CA2246791A1 (en) * | 1998-09-01 | 2000-03-01 | Alison Buchan | Treatment of endothelium with somatostatin analogues |
DE69938005T2 (de) * | 1998-09-22 | 2009-01-15 | Astellas Pharma Inc. | Cyanophenyl-derivate |
GB9902938D0 (en) * | 1999-02-10 | 1999-03-31 | Novartis Ag | Organic compounds |
PE20030240A1 (es) * | 2001-07-09 | 2003-04-16 | Novartis Ag | DERIVADOS DE BENZO [g] QUINOLINA |
FI20031454A0 (fi) | 2003-10-06 | 2003-10-06 | Juvantia Pharma Ltd Oy | Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja |
KR100594234B1 (ko) | 2003-12-05 | 2006-06-30 | 삼성전자주식회사 | 편광 현상을 이용하여 해상도를 향상시킬 수 있는 포토마스크 및 그 제조방법 |
CN101084211A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
JP4958785B2 (ja) | 2004-09-20 | 2012-06-20 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環誘導体およびステアロイル−CoAデサチュラーゼインヒビターとしてのそれらの使用 |
AU2005286648A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
MX2007003318A (es) | 2004-09-20 | 2007-05-18 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como agentes terapeuticos. |
US7767677B2 (en) | 2004-09-20 | 2010-08-03 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
AR051094A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
AU2005286728A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
WO2007130075A1 (en) | 2005-06-03 | 2007-11-15 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
TWI404702B (zh) * | 2007-08-31 | 2013-08-11 | Lundbeck & Co As H | 兒茶酚胺衍生物和其前藥 |
US8067410B2 (en) | 2008-06-27 | 2011-11-29 | H. Lundbeck A/S | Phenolic and catecholic amines and prodrugs thereof |
JP7343170B2 (ja) | 2017-05-12 | 2023-09-12 | ボード オブ トラスティーズ オブ ザ サザン イリノイ ユニバーシティ オン ビハーフ オブ サザン イリノイ ユニバーシティ エドワーズビル | 3,4,5-三置換-1,2,4-トリアゾールおよび3,4,5-三置換-3-チオ-1,2,4-トリアゾール、ならびにそれらの使用 |
US11912687B2 (en) | 2017-05-12 | 2024-02-27 | Board of Trustees of the Southern Illinois University | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof |
CN117599073A (zh) | 2017-11-24 | 2024-02-27 | H.隆德贝克有限公司 | 用于治疗帕金森病的新儿茶酚胺前药 |
US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
JP7099717B2 (ja) | 2019-09-30 | 2022-07-12 | 株式会社理研バイオ | ソマトスタチン受容体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE56958T1 (de) * | 1981-10-16 | 1990-10-15 | Sandoz Ag | 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate mit pharmazeutischer wirkung. |
HU193979B (en) * | 1984-06-12 | 1987-12-28 | Sandoz Ag | Process for producing naphtoxazine derivatives and pharmaceutical compositions containing them |
NL8702680A (nl) * | 1986-11-21 | 1988-06-16 | Sandoz Ag | Nieuwe benzogchinolinen en werkwijzen voor het bereiden en toepassen van deze verbindingen. |
DE4329776A1 (de) * | 1993-09-03 | 1995-03-09 | Sandoz Ag | Naphthoxazine, ihre Herstellung und Verwendung |
-
1996
- 1996-06-12 TW TW085107047A patent/TW357143B/zh active
- 1996-07-05 NZ NZ313606A patent/NZ313606A/xx unknown
- 1996-07-05 US US08/983,535 patent/US5885988A/en not_active Expired - Fee Related
- 1996-07-05 WO PCT/EP1996/002969 patent/WO1997003054A1/en not_active Application Discontinuation
- 1996-07-05 EP EP96925672A patent/EP0839136B1/en not_active Expired - Lifetime
- 1996-07-05 CA CA002224436A patent/CA2224436A1/en not_active Abandoned
- 1996-07-05 CN CN96196551A patent/CN1193964A/zh active Pending
- 1996-07-05 PE PE1996000517A patent/PE1998A1/es not_active Application Discontinuation
- 1996-07-05 ES ES96925672T patent/ES2158327T3/es not_active Expired - Lifetime
- 1996-07-05 CO CO96035363A patent/CO4750662A1/es unknown
- 1996-07-05 RU RU98102128/04A patent/RU2158738C2/ru active
- 1996-07-05 CZ CZ9816A patent/CZ1698A3/cs unknown
- 1996-07-05 TR TR1998/00011T patent/TR199800011T1/tr unknown
- 1996-07-05 AR ARP960103468A patent/AR004672A1/es unknown
- 1996-07-05 HU HU9802937A patent/HUP9802937A3/hu unknown
- 1996-07-05 PL PL96324106A patent/PL324106A1/xx unknown
- 1996-07-05 JP JP9505489A patent/JPH11509197A/ja active Pending
- 1996-07-05 SK SK17-98A patent/SK1798A3/sk unknown
- 1996-07-05 BR BR9609326A patent/BR9609326A/pt active Search and Examination
- 1996-07-05 DE DE69612852T patent/DE69612852T2/de not_active Expired - Fee Related
- 1996-07-05 IL IL12285496A patent/IL122854A/xx not_active IP Right Cessation
- 1996-07-05 DK DK96925672T patent/DK0839136T3/da active
- 1996-07-05 PT PT96925672T patent/PT839136E/pt unknown
- 1996-07-05 KR KR1019980700056A patent/KR19990028757A/ko not_active Application Discontinuation
- 1996-07-05 AT AT96925672T patent/ATE201199T1/de not_active IP Right Cessation
- 1996-07-05 AU AU66120/96A patent/AU703325B2/en not_active Ceased
-
1998
- 1998-01-05 NO NO980043A patent/NO310070B1/no not_active IP Right Cessation
-
2001
- 2001-08-07 GR GR20010401198T patent/GR3036346T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0839136A1 (en) | 1998-05-06 |
RU2158738C2 (ru) | 2000-11-10 |
BR9609326A (pt) | 1999-05-25 |
PE1998A1 (es) | 1998-02-14 |
MX9710530A (es) | 1998-03-31 |
CN1193964A (zh) | 1998-09-23 |
PL324106A1 (en) | 1998-05-11 |
IL122854A (en) | 2000-12-06 |
NO980043D0 (no) | 1998-01-05 |
CO4750662A1 (es) | 1999-03-31 |
EP0839136B1 (en) | 2001-05-16 |
SK1798A3 (en) | 1998-06-03 |
NO310070B1 (no) | 2001-05-14 |
US5885988A (en) | 1999-03-23 |
HUP9802937A2 (hu) | 1999-10-28 |
IL122854A0 (en) | 1998-08-16 |
WO1997003054A1 (en) | 1997-01-30 |
PT839136E (pt) | 2001-09-28 |
AR004672A1 (es) | 1999-03-10 |
AU703325B2 (en) | 1999-03-25 |
NO980043L (no) | 1998-01-05 |
DE69612852D1 (de) | 2001-06-21 |
GR3036346T3 (en) | 2001-11-30 |
DK0839136T3 (da) | 2001-08-06 |
AU6612096A (en) | 1997-02-10 |
KR19990028757A (ko) | 1999-04-15 |
HUP9802937A3 (en) | 2002-10-28 |
CZ1698A3 (cs) | 1998-04-15 |
TW357143B (en) | 1999-05-01 |
JPH11509197A (ja) | 1999-08-17 |
ES2158327T3 (es) | 2001-09-01 |
ATE201199T1 (de) | 2001-06-15 |
DE69612852T2 (de) | 2001-10-04 |
NZ313606A (en) | 1999-07-29 |
CA2224436A1 (en) | 1997-01-30 |
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