TNSN97085A1 - Substitution oxybuterique des acides comme inhibiteurs de la matrice metalloprotease - Google Patents
Substitution oxybuterique des acides comme inhibiteurs de la matrice metalloproteaseInfo
- Publication number
- TNSN97085A1 TNSN97085A1 TNTNSN97085A TNSN97085A TNSN97085A1 TN SN97085 A1 TNSN97085 A1 TN SN97085A1 TN TNSN97085 A TNTNSN97085 A TN TNSN97085A TN SN97085 A TNSN97085 A TN SN97085A TN SN97085 A1 TNSN97085 A1 TN SN97085A1
- Authority
- TN
- Tunisia
- Prior art keywords
- oxybuteric
- substitution
- acids
- metalloprotease
- metalloprotease matrix
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64838496A | 1996-05-15 | 1996-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN97085A1 true TNSN97085A1 (fr) | 2005-03-15 |
Family
ID=24600568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN97085A TNSN97085A1 (fr) | 1996-05-15 | 1997-05-09 | Substitution oxybuterique des acides comme inhibiteurs de la matrice metalloprotease |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0912487A1 (zh) |
JP (1) | JP3417951B2 (zh) |
CN (1) | CN1163466C (zh) |
AR (1) | AR007096A1 (zh) |
AU (1) | AU727648B2 (zh) |
CA (1) | CA2253869C (zh) |
CO (1) | CO4990925A1 (zh) |
HR (1) | HRP970246B1 (zh) |
ID (1) | ID20291A (zh) |
MY (1) | MY132470A (zh) |
PA (1) | PA8429401A1 (zh) |
PE (1) | PE65998A1 (zh) |
SV (1) | SV1997000034A (zh) |
TN (1) | TNSN97085A1 (zh) |
TW (1) | TW467892B (zh) |
WO (1) | WO1997043238A1 (zh) |
YU (1) | YU18797A (zh) |
ZA (1) | ZA974032B (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6288063B1 (en) | 1998-05-27 | 2001-09-11 | Bayer Corporation | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors |
GB0321538D0 (en) | 2003-09-13 | 2003-10-15 | Glaxo Group Ltd | Therapeutically useful compounds |
JP5263548B2 (ja) * | 2007-08-15 | 2013-08-14 | 杏林製薬株式会社 | イブジラストを有効成分とする脳動脈瘤の予防、形成抑制又は治療剤 |
CA2944614A1 (en) | 2014-04-03 | 2015-10-08 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituted cyclopentane carboxylic acids for the treatment of respiratoy tract diseases |
EP3126339A1 (de) | 2014-04-03 | 2017-02-08 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituierte cyclopentancarbonsäuren und ihre verwendung |
JP2017511319A (ja) | 2014-04-03 | 2017-04-20 | バイエル ファーマ アクチエンゲゼルシャフト | キラル2,5−ジ置換されたシクロペンタンカルボン酸誘導体およびそれの使用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR970700652A (ko) * | 1994-01-22 | 1997-02-12 | 포올 리틀우드 | 금속단백질 분해효소 억제제 |
-
1997
- 1997-05-09 TN TNTNSN97085A patent/TNSN97085A1/fr unknown
- 1997-05-09 ZA ZA9704032A patent/ZA974032B/xx unknown
- 1997-05-09 HR HR970246A patent/HRP970246B1/xx not_active IP Right Cessation
- 1997-05-09 CO CO97025164A patent/CO4990925A1/es unknown
- 1997-05-09 MY MYPI97002045A patent/MY132470A/en unknown
- 1997-05-12 EP EP97926454A patent/EP0912487A1/en not_active Withdrawn
- 1997-05-12 CN CNB971964599A patent/CN1163466C/zh not_active Expired - Fee Related
- 1997-05-12 AR ARP970101976A patent/AR007096A1/es unknown
- 1997-05-12 WO PCT/US1997/007975 patent/WO1997043238A1/en not_active Application Discontinuation
- 1997-05-12 JP JP54100297A patent/JP3417951B2/ja not_active Expired - Fee Related
- 1997-05-12 CA CA002253869A patent/CA2253869C/en not_active Expired - Fee Related
- 1997-05-12 AU AU31219/97A patent/AU727648B2/en not_active Ceased
- 1997-05-12 TW TW086106284A patent/TW467892B/zh not_active IP Right Cessation
- 1997-05-12 PA PA19978429401A patent/PA8429401A1/es unknown
- 1997-05-12 SV SV1997000034A patent/SV1997000034A/es not_active Application Discontinuation
- 1997-05-12 YU YU18797A patent/YU18797A/sr unknown
- 1997-05-12 PE PE1997000362A patent/PE65998A1/es not_active Application Discontinuation
- 1997-05-14 ID IDP971607A patent/ID20291A/id unknown
Also Published As
Publication number | Publication date |
---|---|
ZA974032B (en) | 1998-02-19 |
WO1997043238A1 (en) | 1997-11-20 |
MY132470A (en) | 2007-10-31 |
CN1225622A (zh) | 1999-08-11 |
AU3121997A (en) | 1997-12-05 |
JP3417951B2 (ja) | 2003-06-16 |
AR007096A1 (es) | 1999-10-13 |
SV1997000034A (es) | 1999-07-05 |
CA2253869C (en) | 2003-04-22 |
PA8429401A1 (es) | 2000-05-24 |
CA2253869A1 (en) | 1997-11-20 |
CN1163466C (zh) | 2004-08-25 |
AU727648B2 (en) | 2000-12-21 |
TW467892B (en) | 2001-12-11 |
CO4990925A1 (es) | 2000-12-26 |
EP0912487A1 (en) | 1999-05-06 |
PE65998A1 (es) | 1998-10-20 |
ID20291A (id) | 1998-11-19 |
HRP970246A2 (en) | 1998-04-30 |
YU18797A (en) | 1999-11-22 |
JPH11509870A (ja) | 1999-08-31 |
HRP970246B1 (en) | 2002-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA26697A1 (fr) | Composes nouveaux inhibiteurs de gsk-3 et compositions pharmaceutiques les contenant | |
EA200100874A1 (ru) | Полиморфные кристаллические формы целекоксиба | |
ATE208397T1 (de) | Arylsubstituierte 5,5 verknüpfte aromatische nitroverbindungen als entzündungshemmende wirkstoffe | |
AU3249295A (en) | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 | |
WO2002046170A8 (en) | Anilinopyrimidine derivatives as jnk pathway inhibitors and compositions and methods related thereto | |
CA2260016A1 (en) | Substituted pyridines as selective cyclooxygenase-2 inhibitors | |
RU2088589C1 (en) | Derivatives of 17 beta-substituted-4-aza-5-5 alpha-androstane-3-ones, methods of synthesis of compounds, pharmaceutical composition, compound 4 | |
NL300175I1 (nl) | Methylsulfonylfenyl-2-(5H)-furanonen als remmers van COX-2. | |
BR9709501A (pt) | Composto, composição farmacêutica , e, processos para tratar ou prevenir a esquizofrrenia e para sintetizar um composto | |
CA2301742A1 (en) | 2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2 | |
TNSN97085A1 (fr) | Substitution oxybuterique des acides comme inhibiteurs de la matrice metalloprotease | |
DE69533194D1 (de) | PYRAZOLO(3,4-g)CHINOXALINE ALS PDGF-REZEPTOR PROTEIN TYROSIN-KINASE INHIBITOREN | |
CA2254731A1 (en) | Inhibition of matrix metalloproteases by 2-substituted-4-(4-substitutedphenyl)-4-oxobutyric acids | |
BR9503572A (pt) | Composto composiçao farmaceutica e método de tratamento ou prevençao de uma doença | |
ATE235468T1 (de) | Plättchenaggregationsinhibitoren | |
CA2211320A1 (en) | 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2 | |
DE69614392D1 (en) | Thrombin inhibitor | |
Miller et al. | Inhibition of Matrix Metalloproteinases: An examination of the S1′ pocket | |
WO2001003688A3 (en) | Treatment of cyclooxygenase-2 mediated disorders using conjugated fatty acid compounds | |
TNSN97082A1 (fr) | Inhibition des matrices metalloproteases par la substitution des composes phenetyles | |
NZ287551A (en) | N-hydroxyureas that inhibit the 5-lipoxygenase enzyme as anti-inflammatory agents | |
TNSN97081A1 (fr) | Inhibition des matrices metalloproteinases par 2- (w-aroylkyl) -4-biaryl-4-des acides oxubutyriques | |
HUP0301010A2 (hu) | A koleszteril-észter és a viaszészter szintézisét egyaránt gátló vegyületek faggyúmirigy-betegségek kezeléséhez és ezeket tartalmazó gyógyszerkészítmények | |
TNSN97084A1 (fr) | Biaryl acetylenes comme inhibiteurs des matrices metalloproteinases | |
PL313037A1 (en) | Phenoxphenylocyclopententenylohydroxyureas |