TNSN95083A1 - Heteroaryl-oxazolidinones a 5 membres - Google Patents

Heteroaryl-oxazolidinones a 5 membres

Info

Publication number
TNSN95083A1
TNSN95083A1 TNTNSN95083A TNSN95083A TNSN95083A1 TN SN95083 A1 TNSN95083 A1 TN SN95083A1 TN TNSN95083 A TNTNSN95083 A TN TNSN95083A TN SN95083 A TNSN95083 A TN SN95083A TN SN95083 A1 TNSN95083 A1 TN SN95083A1
Authority
TN
Tunisia
Prior art keywords
oxazolidinones
heteroaryl
members
medicinal products
medicaments
Prior art date
Application number
TNTNSN95083A
Other languages
English (en)
Inventor
Bernd Riedl Dr
Dieter Habich Dr
Andreas Stolle Dr
Hanno Wild Dr
Rainer Endermann Dr
Klaus Dieter Bremm Dr
Hein-Peter Kroll Dr
Dr Harald Labischinski Prof
Klaus Schaller Dr
Hans-Otto Werling Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of TNSN95083A1 publication Critical patent/TNSN95083A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENTION SE RAPPORTE A DES HETEROARYL- OXAZOLIDINONES A 5 MEMBRES, A DES PROCEDES POUR LEUR PREPARATION ET A LEUR UTILISATION COMME MEDICAMENTS, EN PARTICULIER COMME MEDICAMENTS , EN PARTICULIER COMME MEDICAMENTS ANTIBACTERIENS.
TNTNSN95083A 1994-07-20 1995-07-19 Heteroaryl-oxazolidinones a 5 membres TNSN95083A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425613A DE4425613A1 (de) 1994-07-20 1994-07-20 5-gliedrige Heteroaryl-oxazolidinone

Publications (1)

Publication Number Publication Date
TNSN95083A1 true TNSN95083A1 (fr) 1996-02-06

Family

ID=6523633

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN95083A TNSN95083A1 (fr) 1994-07-20 1995-07-19 Heteroaryl-oxazolidinones a 5 membres

Country Status (28)

Country Link
US (1) US5698574A (fr)
EP (1) EP0693491A1 (fr)
JP (1) JPH0853443A (fr)
KR (1) KR960004343A (fr)
CN (1) CN1121919A (fr)
AU (1) AU695661B2 (fr)
BG (1) BG99791A (fr)
CA (1) CA2154026A1 (fr)
CO (1) CO4410193A1 (fr)
CZ (1) CZ187395A3 (fr)
DE (1) DE4425613A1 (fr)
EE (1) EE9500044A (fr)
FI (1) FI953476A (fr)
HR (1) HRP950391A2 (fr)
HU (1) HUT74003A (fr)
IL (1) IL114622A (fr)
MA (1) MA23621A1 (fr)
NO (1) NO304488B1 (fr)
NZ (1) NZ272596A (fr)
PE (1) PE35896A1 (fr)
PL (1) PL309685A1 (fr)
RO (1) RO115161B1 (fr)
RU (1) RU95113086A (fr)
SK (1) SK91695A3 (fr)
SV (1) SV1995000042A (fr)
TN (1) TNSN95083A1 (fr)
YU (1) YU49195A (fr)
ZA (1) ZA956015B (fr)

Families Citing this family (69)

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DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
US6124334A (en) * 1995-02-03 2000-09-26 Pharmacia & Upjohn Company Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
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DE19601264A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) * 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
EP0920421B1 (fr) * 1996-08-21 2002-11-06 PHARMACIA & UPJOHN COMPANY Derives d'isoxazoline utiles comme agents antimicrobiens
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
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GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
EP1049682A1 (fr) 1998-01-23 2000-11-08 Versicor, Inc. Banques combinatoires d'oxazolidinones, compositions a base de tels composes et procedes de preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6262044B1 (en) * 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
US6110962A (en) * 1998-05-12 2000-08-29 American Home Products Corporation 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia
JP2002516321A (ja) * 1998-05-12 2002-06-04 アメリカン・ホーム・プロダクツ・コーポレイション インスリン耐性および高血糖の治療に有用なベンゾチオフェン、ベンゾフラン、およびインドール
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6121271A (en) * 1998-05-12 2000-09-19 American Home Products Corporation Naphtho[2,3-B]heteroar-4-yl derivatives
AU4072799A (en) 1998-05-12 1999-12-13 American Home Products Corporation 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
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AR020660A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Composiciones antibioticas para el tratamiento de ojos, oidos y nariz
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US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
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US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
US6544991B2 (en) 2000-06-30 2003-04-08 Pharmacia & Upjohn Company Compositions and methods for treating bacterial infections
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
WO2002018354A1 (fr) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones et leur utilisation en tant qu'agents antibacteriens
PE20020578A1 (es) 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
US6689769B2 (en) 2000-12-21 2004-02-10 Pharmacia & Upjohn Company Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
JP2003192773A (ja) * 2001-12-26 2003-07-09 Mitsui Chemicals Inc 生体吸収性ポリヒドロキシカルボン酸及びその製造法
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Also Published As

Publication number Publication date
JPH0853443A (ja) 1996-02-27
NO952866L (no) 1996-01-22
AU2498895A (en) 1996-02-01
NO304488B1 (no) 1998-12-28
FI953476A0 (fi) 1995-07-18
BG99791A (en) 1996-04-30
FI953476A (fi) 1996-01-21
SV1995000042A (es) 1996-03-28
CO4410193A1 (es) 1997-01-09
HUT74003A (en) 1996-10-28
RU95113086A (ru) 1997-06-27
EE9500044A (et) 1996-02-15
AU695661B2 (en) 1998-08-20
DE4425613A1 (de) 1996-01-25
EP0693491A1 (fr) 1996-01-24
CN1121919A (zh) 1996-05-08
SK91695A3 (en) 1996-02-07
NZ272596A (en) 1997-03-24
PE35896A1 (es) 1996-10-14
YU49195A (sh) 1998-12-23
NO952866D0 (no) 1995-07-19
CA2154026A1 (fr) 1996-01-21
HU9502167D0 (en) 1995-09-28
IL114622A0 (en) 1995-11-27
US5698574A (en) 1997-12-16
CZ187395A3 (en) 1996-02-14
IL114622A (en) 1999-07-14
KR960004343A (ko) 1996-02-23
HRP950391A2 (en) 1997-06-30
MA23621A1 (fr) 1996-04-01
PL309685A1 (en) 1996-01-22
ZA956015B (en) 1996-02-22
RO115161B1 (ro) 1999-11-30

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