TNSN88118A1 - PROCESS FOR THE PREPARATION OF GINKGOLID DERIVATIVES - Google Patents
PROCESS FOR THE PREPARATION OF GINKGOLID DERIVATIVESInfo
- Publication number
- TNSN88118A1 TNSN88118A1 TNTNSN88118A TNSN88118A TNSN88118A1 TN SN88118 A1 TNSN88118 A1 TN SN88118A1 TN TNSN88118 A TNTNSN88118 A TN TNSN88118A TN SN88118 A TNSN88118 A TN SN88118A TN SN88118 A1 TNSN88118 A1 TN SN88118A1
- Authority
- TN
- Tunisia
- Prior art keywords
- derivatives
- preparation
- ginkgolid
- ethyl ethyl
- alcoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Abstract
LA PRESENTE INVENTION CONCERNE UN PROCEDE DE PREPARATION DE DERIVES ALCOXY-1 OU ALCOXY-10 DES GINKGOLIDES CONSISTANT A FAIRE REAGIR UNE SOLUTION DE DIOXANE D'UN GINKGOLIDE CHOISI AVEC UNE SOLUTION DANS L'ETHER ETHYLIQUE DE DIAZOALCANE EN EXCES, A TEMPERATURE AMBIANTE, PENDANT UNE A DIX HEURES.THE PRESENT INVENTION CONCERNS A PROCESS FOR THE PREPARATION OF ALCOXY-1 OR ALCOXY-10 DERIVATIVES OF GINKGOLIDES CONSISTING OF REACTING A DIOXANE SOLUTION OF A GINKGOLIDE SELECTED WITH A SOLUTION IN ETHYL ETHYL ETHYL ETHYL ETHYL ETHYL ETHYL ATHANTIC EXPERIMENT ONE TO TEN HOURS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878725871A GB8725871D0 (en) | 1987-11-04 | 1987-11-04 | Ginkgolide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN88118A1 true TNSN88118A1 (en) | 1990-07-10 |
Family
ID=10626449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN88118A TNSN88118A1 (en) | 1987-11-04 | 1988-11-03 | PROCESS FOR THE PREPARATION OF GINKGOLID DERIVATIVES |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPH0686455B2 (en) |
| KR (1) | KR970005536B1 (en) |
| AT (1) | AT397097B (en) |
| AU (1) | AU616367B2 (en) |
| BE (1) | BE1003455A3 (en) |
| CA (1) | CA1303619C (en) |
| CH (1) | CH675583A5 (en) |
| DE (1) | DE3837550A1 (en) |
| DK (1) | DK612788A (en) |
| ES (1) | ES2009364A6 (en) |
| FI (1) | FI90081C (en) |
| FR (2) | FR2622448B1 (en) |
| GB (2) | GB8725871D0 (en) |
| GR (1) | GR1000264B (en) |
| HK (1) | HK53992A (en) |
| IE (1) | IE61541B1 (en) |
| IN (1) | IN173404B (en) |
| IT (1) | IT1227456B (en) |
| MA (1) | MA21423A1 (en) |
| MY (1) | MY103446A (en) |
| NL (1) | NL8802635A (en) |
| NO (1) | NO167739C (en) |
| NZ (1) | NZ226738A (en) |
| PT (1) | PT88924B (en) |
| SE (1) | SE8803931L (en) |
| SG (1) | SG48292G (en) |
| TN (1) | TNSN88118A1 (en) |
| ZA (1) | ZA888184B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5895785A (en) * | 1987-10-20 | 1999-04-20 | Ruth Korth | Treatment and prevention of disorders mediated by LA-paf or endothelial cells |
| EP0459432B1 (en) * | 1990-06-01 | 2000-08-23 | Korth, Ruth, Dr. med. | Treatment of diseases with paf-antagonists and procedure for determining their efficacy |
| ATE221779T1 (en) * | 1991-11-04 | 2002-08-15 | Ruth-Maria Korth | TREATMENT AND PREVENTION OF ELEVATED LYSO-PAF LEVELS-MEDIATED MENTAL DISEASES USING PAF ANTAGONISTS |
| FR2763592B1 (en) * | 1997-05-20 | 1999-07-16 | Sod Conseils Rech Applic | NOVEL GLYCOSYL DERIVATIVES OF GINKGOLIDES, THEIR APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| FR2777280B1 (en) * | 1998-04-10 | 2001-04-20 | Centre Nat Rech Scient | GINKGOLIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CN106892930B (en) | 2015-12-18 | 2020-02-18 | 成都百裕金阁莱药业有限公司 | Bilobalide B derivative and preparation method and application thereof |
| CN108383852B (en) * | 2017-12-25 | 2019-11-22 | 上海信谊百路达药业有限公司 | A kind of Ginkgolid extracted from ginkgo leaf and its preparation |
| CN108373474B (en) * | 2017-12-25 | 2020-06-09 | 上海信谊百路达药业有限公司 | A bilobalide compound extracted from folium Ginkgo and its preparation method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8418424D0 (en) * | 1984-07-19 | 1984-08-22 | Scras | Inhibition of platelets aggregation |
| DE3710921C2 (en) * | 1986-10-21 | 1996-09-26 | Korth Ruth | Use of Gingkolide BN 52020, BN 52021 and BN 52063 for the treatment of arteriosclerosis |
| DE3735525C2 (en) * | 1987-10-20 | 1997-02-20 | Korth Ruth Maria | Method for determining the efficacy of paf-acether receptor antagonists |
-
1987
- 1987-11-04 GB GB878725871A patent/GB8725871D0/en active Pending
-
1988
- 1988-10-24 GB GB8824859A patent/GB2211841B/en not_active Expired - Fee Related
- 1988-10-26 NL NL8802635A patent/NL8802635A/en not_active Application Discontinuation
- 1988-10-26 GR GR880100726A patent/GR1000264B/en unknown
- 1988-10-26 IN IN928DE1988 patent/IN173404B/en unknown
- 1988-10-27 NZ NZ226738A patent/NZ226738A/en unknown
- 1988-10-28 MY MYPI88001236A patent/MY103446A/en unknown
- 1988-10-28 BE BE8801244A patent/BE1003455A3/en not_active IP Right Cessation
- 1988-10-31 SE SE8803931A patent/SE8803931L/en not_active Application Discontinuation
- 1988-11-01 ZA ZA888184A patent/ZA888184B/en unknown
- 1988-11-01 MA MA21665A patent/MA21423A1/en unknown
- 1988-11-02 FI FI885046A patent/FI90081C/en not_active IP Right Cessation
- 1988-11-02 AT AT0269688A patent/AT397097B/en not_active IP Right Cessation
- 1988-11-02 ES ES8803334A patent/ES2009364A6/en not_active Expired
- 1988-11-03 AU AU24644/88A patent/AU616367B2/en not_active Ceased
- 1988-11-03 IE IE331588A patent/IE61541B1/en not_active IP Right Cessation
- 1988-11-03 KR KR1019880014439A patent/KR970005536B1/en active IP Right Grant
- 1988-11-03 CA CA000582165A patent/CA1303619C/en not_active Expired - Fee Related
- 1988-11-03 CH CH4081/88A patent/CH675583A5/fr not_active IP Right Cessation
- 1988-11-03 DK DK612788A patent/DK612788A/en not_active Application Discontinuation
- 1988-11-03 NO NO884900A patent/NO167739C/en unknown
- 1988-11-03 PT PT88924A patent/PT88924B/en not_active IP Right Cessation
- 1988-11-03 TN TNTNSN88118A patent/TNSN88118A1/en unknown
- 1988-11-04 FR FR888814393A patent/FR2622448B1/en not_active Expired - Fee Related
- 1988-11-04 DE DE3837550A patent/DE3837550A1/en active Granted
- 1988-11-04 FR FR888814392A patent/FR2622584B1/en not_active Expired - Fee Related
- 1988-11-04 IT IT8822493A patent/IT1227456B/en active
- 1988-11-04 JP JP63277522A patent/JPH0686455B2/en not_active Expired - Lifetime
-
1992
- 1992-04-29 SG SG48292A patent/SG48292G/en unknown
- 1992-07-23 HK HK539/92A patent/HK53992A/en not_active IP Right Cessation
Also Published As
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