TNSN08286A1 - Stabilisation de testosterone au sein de dispositifs transdermiques - Google Patents

Stabilisation de testosterone au sein de dispositifs transdermiques

Info

Publication number
TNSN08286A1
TNSN08286A1 TNP2008000286A TNSN08286A TNSN08286A1 TN SN08286 A1 TNSN08286 A1 TN SN08286A1 TN P2008000286 A TNP2008000286 A TN P2008000286A TN SN08286 A TNSN08286 A TN SN08286A TN SN08286 A1 TNSN08286 A1 TN SN08286A1
Authority
TN
Tunisia
Prior art keywords
testosterone
stabilization
transdermal devices
desiccant
chemical
Prior art date
Application number
TNP2008000286A
Other languages
English (en)
Inventor
Joel Bougaret
Michel Sournac
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of TNSN08286A1 publication Critical patent/TNSN08286A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

La présente invention concerne la stabilisation chimique de la testosterone contenue dans des dispositfs transdermiques autoadhésifs via l'association d'un agent dessicant avec ledit dispositif au sein d'un emballage étanche. L'utilisation d'un agent dessicant permet de limiter la dégradation chimique de la testostérone en androsténedione et autres impuretés et assure ainsi une conservation dudit dispositif sur des durées allant jusqu'a trente-six mois.
TNP2008000286A 2005-12-29 2008-06-27 Stabilisation de testosterone au sein de dispositifs transdermiques TNSN08286A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0513435A FR2895679B1 (fr) 2005-12-29 2005-12-29 Stabilisation de testosterone au sein de dispositifs transdermiques
PCT/FR2006/002873 WO2007074239A1 (fr) 2005-12-29 2006-12-26 Stabilisation de testosterone au sein de dispositifs transdermiques.

Publications (1)

Publication Number Publication Date
TNSN08286A1 true TNSN08286A1 (fr) 2009-10-30

Family

ID=37075280

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2008000286A TNSN08286A1 (fr) 2005-12-29 2008-06-27 Stabilisation de testosterone au sein de dispositifs transdermiques

Country Status (18)

Country Link
US (1) US20080317859A1 (fr)
EP (1) EP1965749A1 (fr)
JP (1) JP2009522243A (fr)
KR (1) KR20080081166A (fr)
CN (1) CN101351180A (fr)
AU (1) AU2006329751A1 (fr)
BR (1) BRPI0620839A2 (fr)
CA (1) CA2635422A1 (fr)
FR (1) FR2895679B1 (fr)
IL (1) IL192406A0 (fr)
MA (1) MA30015B1 (fr)
NO (1) NO20083306L (fr)
NZ (1) NZ568658A (fr)
RU (1) RU2419436C2 (fr)
TN (1) TNSN08286A1 (fr)
UA (1) UA97354C2 (fr)
WO (1) WO2007074239A1 (fr)
ZA (1) ZA200805157B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2018098501A1 (fr) 2016-11-28 2018-05-31 Lipocine Inc. Traitement oral à base d'undécanoate de testostérone

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
DE19517145C2 (de) * 1995-05-10 2000-02-24 Hexal Pharmaforschung Gmbh Transdermales therapeutisches System (TTS) zur Verabreichung von Testosteron
US5698217A (en) * 1995-05-31 1997-12-16 Minnesota Mining And Manufacturing Company Transdermal drug delivery device containing a desiccant
CA2273921C (fr) * 1996-12-03 2005-10-25 Minnesota Mining And Manufacturing Company Distributeurs de timbres transdermiques/transmuqueux
GB9720470D0 (en) * 1997-09-25 1997-11-26 Ethical Pharmaceuticals South Inhibition of crystallization in transdermal devices
DE19913761B4 (de) * 1999-03-26 2005-02-10 Lts Lohmann Therapie-Systeme Ag Trocknungsvorrichtung und Verfahren zu ihrer Herstellung sowie ihre Verwendung
FR2793689B1 (fr) * 1999-05-19 2001-08-24 Pf Medicament Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives
DE19925613A1 (de) * 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Verbundlaminat und Verfahren zu seiner Herstellung
US6905016B2 (en) * 2000-03-14 2005-06-14 Noven Pharmaceuticals, Inc. Packaging system for transdermal drug delivery systems

Also Published As

Publication number Publication date
EP1965749A1 (fr) 2008-09-10
RU2419436C2 (ru) 2011-05-27
KR20080081166A (ko) 2008-09-08
AU2006329751A1 (en) 2007-07-05
CA2635422A1 (fr) 2007-07-05
FR2895679B1 (fr) 2012-06-08
ZA200805157B (en) 2009-06-24
NO20083306L (no) 2008-09-16
FR2895679A1 (fr) 2007-07-06
US20080317859A1 (en) 2008-12-25
UA97354C2 (ru) 2012-02-10
MA30015B1 (fr) 2008-12-01
IL192406A0 (en) 2008-12-29
CN101351180A (zh) 2009-01-21
JP2009522243A (ja) 2009-06-11
WO2007074239A1 (fr) 2007-07-05
RU2008131064A (ru) 2010-02-10
NZ568658A (en) 2011-10-28
BRPI0620839A2 (pt) 2011-11-29

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