TH9821C3 - Preparation process of Inthanin flower extract with high phenolic flavonoids and anthocyanin. And has an activity to inhibit collagen breakdown enzymes - Google Patents

Abstract

DC60 (27/06/57) Inthanin flower extract preparation process with high phenolic flavonoid anthocyanin and inhibiting enzyme for collagen breakdown. It is the development of extraction methods for extracting high content phenolic, flyvonoid and anthocyanins from Inthanin petals. By fermentation in organic solvents mixed with water and using low temperature dry extracts in conjunction with evaporation dry at high cold in vacuum condition, the extracted was purple-brown dry powder, dissolving well both In water and alcohol, a previously previously reported activity was found to be inhibited by the enzyme matrix metalloprotinase that breaks down collagen. Used as an important drug in skin care products or in case of Abnormal in the breakdown of collagen This is an invention that not only supports the use of Thai herbs, but also increases the value of Thai flowers that, apart from being ornamental plants, are also useful in being used as ones. Essential drugs for developing good skin care products Inthanin flower extract preparation process with high phenolic, flavonoids, anthocyanin and inhibiting enzyme for collagen breakdown was the development of the extraction process of the important phenolic group. High content of vonoid and anthocyanin from the inthanin flower petals. By fermentation in organic solvent mixed with water and using low temperature starch extracts together with evaporation dry at high cold in vacuum condition, the extracted extract was dry powder, purple brown, dissolving well both In water and alcohol, and a previously previously reported activity was discovered, which is a curbing effect on the enzyme matrix metalloprotinase that breaks down collagen. To be an important drug in skin care products or when Abnormalities in the breakdown of collagen This is an invention that not only supports the use of Thai herbs, but also increases the value of Thai flowers that, apart from being ornamental plants, are also useful in being used as ones. Essential drugs for developing good skin care products

Claims (1)

1. Method for preparing Inthanin flower extract with high phenolic flavonoids and anthocyanin and inhibiting enzyme for collagen breakdown. The steps are as follows: a. Only the reddish-purple petals of the Inthanin flower are dried at 45 degrees Celsius for 2 days and ground with a dry grinding machine until particle size is 200-250 microns. Inthanin flower petals dried from Section A. are soaked in a mixture containing distilled water and alcohol (1: 1) by soaking in a ratio of 1:18, shaking well at a temperature of 20-25 ° C and in a container that Opaque until the Inthanin flower powder swelled fully. Then continue to ferment by stirring periodically with a stick stirrer. Magnet times for 20 minutes, 15-20 times a day, for 5 days. C. Take the fermented part from item B. Subsequently, pass the No. 1 filter paper. Dip the extracts that are filtered through the filter paper from Article C. Remove the alcohol using the machine. Evaporate, rotary dry at 45 ° C for 6-10 hours until the extracts become viscous, remaining 1 part of the total solution. E. Dry the parts from section D and dry with a cold dryer at temperature. -50 degrees Celsius for 1-2 days until the extract was completely dried purple powder which gave% yield of 22 which It has good solubility in both water and alcohol.