TH289A - New derivatives of Imidazole - Google Patents
New derivatives of ImidazoleInfo
- Publication number
- TH289A TH289A TH8101000139A TH8101000139A TH289A TH 289 A TH289 A TH 289A TH 8101000139 A TH8101000139 A TH 8101000139A TH 8101000139 A TH8101000139 A TH 8101000139A TH 289 A TH289 A TH 289A
- Authority
- TH
- Thailand
- Prior art keywords
- hydrogen
- formula
- group
- fluorine
- methyl
- Prior art date
Links
- 150000002460 imidazoles Chemical class 0.000 title claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 5
- 239000001257 hydrogen Substances 0.000 claims abstract 5
- 239000000126 substance Substances 0.000 claims abstract 5
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims abstract 4
- 125000000217 alkyl group Chemical group 0.000 claims abstract 4
- 229910052731 fluorine Inorganic materials 0.000 claims abstract 4
- 239000011737 fluorine Substances 0.000 claims abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 4
- -1 hydroxy, methoxy Chemical group 0.000 claims abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000005977 Ethylene Substances 0.000 claims abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- 125000001544 thienyl group Chemical group 0.000 claims abstract 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000035479 physiological effects, processes and functions Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Abstract
1.มีการเตรียมอนุพันธุ์ชนิดใหม่ของอิมิดาโซล ซึ่งมีสูตร(สูตรเคมี) ซึ่ง X คือ ไฮโดรเจน หรือ C1-4 นอร์มาลอัลคิล และ Y คือ ไธเอนนิลที่ถูกเลือกแทนที่โดยเมทธิล หรือฟลูออรีน หรือหมู่หนึ่งซึ่งมีสูตร (สูตรเคมี) ซึ่ง R1, R2 และ R3 คือ ไฮโดรเจน,เมทธิล,ฟลูออรีน, ไฮดรอกซี, เมทธอกซี หรือสองหมู่ของ R1, R2, R3 บนอะตอมของคาร์บอนที่อยู่ติดกันคือ เมทธิลลีนไดออกซีทั้งคู่ หรือคือเอทธิลลีนไดออกซีทั้งคู่ หรือหมู่หนึ่งของ R1, R2 และ R3 คือ โมโน-หรือ ได-(C1-4) -นอร์มาลอัลคิล)-อมิโน และอีกสองหมู่คือ ไฮโดรเจน และเกลือที่ได้จากการเติมกรดของสารเหล่า นี้ซึ่งใช้ในทางสรีรวิทยาได้ สรีรวิทยาได้ สิทธิบัตรยา 1. A new species of Imidazole has been prepared. Which has the formula (chemical formula) where X is hydrogen or C1-4 normal alkyl and Y is thienyl selected replaced by methyl or fluorine or a group with the formula (chemical formula) where R1 , R2 and R3 are hydrogen, methyl, fluorine, hydroxy, methoxy or two groups of R1, R2, R3 on the adjacent carbon atoms are Methylene Dioxy, Both Or is it ethylene dioxide both? Or a group of R1, R2 and R3 is mono- or di- (C1-4) -normal alkyl) -amino. And the other two groups are hydrogen and salt obtained from the addition of acidic substances. This, which is used in physiology, has a patent physiological drug.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH289A true TH289A (en) | 1982-04-30 |
Family
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