TH128830A - Substitutate propanilpiperazine is a new type of inhibitor of histone deacetylase. - Google Patents
Substitutate propanilpiperazine is a new type of inhibitor of histone deacetylase.Info
- Publication number
- TH128830A TH128830A TH501003450A TH0501003450A TH128830A TH 128830 A TH128830 A TH 128830A TH 501003450 A TH501003450 A TH 501003450A TH 0501003450 A TH0501003450 A TH 0501003450A TH 128830 A TH128830 A TH 128830A
- Authority
- TH
- Thailand
- Prior art keywords
- propanilpiperazine
- substitutate
- inhibitor
- new type
- histone deacetylase
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 102000003964 Histone deacetylases Human genes 0.000 title 1
- 108090000353 Histone deacetylases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 3
- 229940079593 drugs Drugs 0.000 claims abstract 3
- 150000001204 N-oxides Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 230000024881 catalytic activity Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
Abstract
DC60 (07/03/56) การประดิษฐ์นี้ประกอบด้วยสารประกอบใหม่สูตร (I) (สูตรเคมี) (I) ซึ่ง R1, R2, R3, R4 และ X มีความหมายเหมือนกับที่นิยามมาแล้ว, มีความว่องไวของเอนไซม์ที่ยับยั้ง ฮิสโทน ดีแอเซทิเลส, สมบัติของมัน, องค์ประกอบของสารเหล่านั้น, และการใช้สารเหล่านั้นเป็นยา การประดิษฐ์นี้ประกอบด้วยสารประกอบใหม่สูตร (I) (สูตรเคมี) (I) ซึ่ง R1, R2, R3, R4 และ X มีความหมายเหมือนกับที่นิยามมาแล้ว, มีความว่องไวของเอนไซม์ที่ยับยั้ง ฮิสโทน ดีแอเซทิเลส, สมบัติของมัน, สารผสมของสารเหล่านั้น, และการใช้สารเหล่านั้นเป็นยา สิทธิบัตรยา DC60 (07/03/56) This invention contains a new compound, formula (I) (chemical formula) (I), which R1, R2, R3, R4 and X are synonymous with previously defined, with inhibitory enzyme activity. Histone dacetylase, their properties, their composition, and their use as drugs. The invention consists of a new compound, formula (I) (chemical formula) (I), which R1, R2, R3, R4 and X are synonymous with previously defined, with the enzyme activity that inhibits histone diazetele. Their properties, mixtures of those substances, and their use as drugs.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH128830A true TH128830A (en) | 2013-11-07 |
| TH128830B TH128830B (en) | 2013-11-07 |
Family
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