TH105084A - - Google Patents
Info
- Publication number
- TH105084A TH105084A TH701000513A TH0701000513A TH105084A TH 105084 A TH105084 A TH 105084A TH 701000513 A TH701000513 A TH 701000513A TH 0701000513 A TH0701000513 A TH 0701000513A TH 105084 A TH105084 A TH 105084A
- Authority
- TH
- Thailand
- Prior art keywords
- methyl
- ethyl
- salt
- pteridinyl
- tetrahydro
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims abstract 5
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000011780 sodium chloride Substances 0.000 abstract 3
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
Abstract
DC60 (02/05/50) การประดิษฐ์นี้เกี่ยวข้องกับเกลือที่จำเพาะของอนุพันธ์ไดไฮโดรพ์เทอริไดโอนกล่าวคือ เกลือ ไตรไฮโดรคลอไรด์ของสารประกอบ N-[ทรานส์-4-[4-(ไซโคลโพรพิลเมทิล)-1-พิเพอราซินิล]ไซโคล เฮกซิล]-4-[[(7R)-7-เอทิล-5,6,7,8-เตตราไฮโดร-5-เมทิล-8-(1-เมทิลเอทิล)-6-ออกโซ-2-พเทอริดินิล] อะมิโน]-3-เมทอกซี-เบนซาไมด์, การตกผลึกสารดังกล่าวในรูปของไฮเดรตด้วยน้ำ, กระบวนการใน การผลิตสารดังกล่าว และการใช้สารดังกล่าวในสารผสมทางเภสัชกรรม การประดิษฐ์นี้เกี่ยวข้องกับเกลือที่จำเพาะของอนุพันธ์ไดไฮโดรพ์เทอริไดโอนกล่าวคือ เกลือ ไตรไฮโดรคลอไรด์ของสารประกอบ N-[ทรานส์-4-[4-(ไซโคลโพรพิมเมทิล)-1-พิเพอราซินิล]ไซโคล เฮกซิล]-4-[[(7R)-7-เอทิล-5,6,7,8-เตตราไฮโดร-5-เมทิล-8-(1-เมทิลเอทิล)-6-ออกโซ-2-พเทอริดินิล] อะมิโน]-3-เมทอกซี-เบนซาไมด์, การตกผลึกสารดังกล่าวในรูปของไฮเดรตด้วยน้ำ, กระบวนการใน การผลิตสารดังกล่าว และการใช้สารดังกล่าวในสารผสมทางเภสัชกรรม สิทธิบัตรยา DC60 (02/05/50) This invention involves a specific salt of the dihydroptheridion derivative, that is, the tri-hydrochloride salt of the compound. N- [trans-4- [4- (cyclopropyl methyl) -1-piperasinil] cyclo Hexyl] -4 - (((7R) -7- ethyl -5,6,7,8-tetrahydro-5-methyl-8- (1-methyl ethyl) -6-oxo-2- Pteridinyl] amino] -3-methoxy-benzamide, to crystallize it as a water hydrate, process to produce it. And the use of such substances in pharmaceutical mixtures The invention involved a specific salt of the dihydroptheriodion derivative, that is, the trihydrochloride salt of the compound. N- [trans-4- [4- (cyclopropymethyl) -1-piperacinil] cyclo Hexyl] -4 - (((7R) -7- ethyl -5,6,7,8-tetrahydro-5-methyl-8- (1-methyl ethyl) -6-oxo-2- Pteridinyl] amino] -3-methoxy-benzamide, to crystallize it as a water hydrate, process to produce it. And their use in pharmaceutical mixtures, drug patents
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH105084B TH105084B (en) | 2010-11-27 |
| TH105084A true TH105084A (en) | 2010-11-27 |
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