SU774552A1 - Method of treating viral keratoiridocyclitis and iridocyclitis - Google Patents

Description

This invention relates to the field of medicine, namely ophthalmology. There is a method of treating viral keratoiridocyclitis and iridocyclitis by puncture of the anterior chamber of the eye, followed by suction of the aqueous humid chamber. However, the average duration of treatment in a known manner is long and is 45.6 ± 10.5 days. The aim of the invention is to reduce the duration of treatment. This goal is achieved by introducing interferon or interferonogen, pre-dissolved in physiological saline solution after suction, which is mixed with the patient's autoplasma in a ratio of 1: 1.5 to 1: 2, respectively. The method is carried out as follows. The paracentres are made with a Sato knife (they do not place a horizontal meridi of 1.5-2 mm from the limbus). A system connected to two syringes is introduced into the anterior through a hole in the cornea. Syringes in turn are connected to two silicone tubes through a tee. Through the system, a part of the chamber moisture (0.1 0.2) is suctioned out, followed by the introduction of interferon preparation (or stimulator of its formation) from another syringe of the same system, dissolved in the patient's plasma. The total volume of the injected mixture is 0.15-0.3 ml. Interferon or interferonogen is pre-dissolved in 0.5 medium 199 or physiological pact, and then poured into a syringe with a sterile autoplasma of the patient in an amount of 0.7 ml, taken 1 hour before the operation and for 30 minutes subjected to centrifugation. The interferon content is 150-300 units, and the interferonogen 50-100 µg. In the case of any openness of the corneal micro-area, a stitch may be applied. Under the conjunctiva of the eye, an antibiotic solution is injected, a binocular band is applied. Bed re- The press is observed during the day. Patients with keratoiridocyclitgy during 5-6 hours after surgery are in bed in the face-down position. The operation is carried out depending on the testimony from 1 to 3 times. The indications in this operation are viral etiology iridocyclitis and keratoiridocyclitis, starting after iridocyclitis

and proceeding without removal of the anterior corneal surface.

Example. Patient Xc 42 years old was admitted to the hospital with a diagnosis; bullous keratoiridocyclitis with increased intraocular pressure of the left eye, the right eye is healthy.

The viral nature of the disease was confirmed by an immunofluorescence study of a conjunctivitis scrape. Before going to the clinic, the patient received complex treatment according to the usual procedure in the clinic at the place of residence for 2.5 months.

Admission: the right eye is healthy. Visual acuity 1.0. The left eye - blepharospasm, lacrimation, pronounced mixed injection of the eye block. The sensitivity of the cornea is sharply reduced, in the central part of it is almost completely absent. The corneal epithelium is swollen in the form of blisters. The cut of the cornea is thick (almost twice as compared to the norm), not completely uniform. The endothelium is swollen, overlaying it in the form of large gray precipitates and fine dust. Moisture anterior chamber opalescent. Iris is swollen, full of blood. The pupil is 4.5 mm in diameter, of irregular shape. Deep-seated environments of the eye block cannot be considered due to changes in the cornea. Intraocular pressure - (+) 1, Acuity of the vision of the left eye 0.02 n / box.

An intracameral injection of interferon with the patient's autoplasma into the left eye was performed using the proposed method without corneal stitches.

on the 3rd day after the operation - edema of the left eye is 0.2. The remains of edema and corneal infiltration. Small single precipitates.

On the 9th day after the operation, visual acuity was 0.9. Corneal edema has almost completely disappeared. Small single precipitates are preserved.

The patient was discharged on the 15th day after admission with an acute vision of 1.0. Intraocular pressure returned to normal. A gentle opacification is maintained on the cornea, which does not affect the acuity of the patient's vision.

The proposed method allows to significantly reduce treatment time compared to the known.

Comparative data are presented in the table.

invention formula

A method of treating viral keratoiridocyclitis and iridocyclitis by puncturing the anterior chamber of the eye followed by suctioning out the aqueous humor of the chamber, characterized in that, to reduce the eaters of treatment, after suction, the interferon or interferonogen previously dissolved in saline, which is mixed with the autoplasm of the patient's blood, is administered in a ratio of 1: 1.51: 2, respectively.

Claims (1)

Claim SP Method ^{6 of treatment of} viral keratoiridocyclitis and iridocyclitis by puncture of the anterior chamber of the eye followed by suction of the aqueous humor of the chamber, characterized in that, in order to reduce treatment consumers, interferon or interferonogen is introduced after aspiration, which is previously dissolved in physiological saline, which is mixed with the patient’s blood plasma 40 in a ratio of 1: 1.51: 2, respectively.