SU76390A1 - The method of obtaining 2-phenyl-4-alkohsimetilen-okeazolinone-5 - Google Patents
The method of obtaining 2-phenyl-4-alkohsimetilen-okeazolinone-5Info
- Publication number
- SU76390A1 SU76390A1 SU146A SU389262A SU76390A1 SU 76390 A1 SU76390 A1 SU 76390A1 SU 146 A SU146 A SU 146A SU 389262 A SU389262 A SU 389262A SU 76390 A1 SU76390 A1 SU 76390A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- phenyl
- okeazolinone
- alkohsimetilen
- obtaining
- ether
- Prior art date
Links
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Description
СО с-CsHj /CO c-CsHj /
Пример I. 7,2 г гиппуровой кис-лоты смешивают с 6 г ортомуравьиного эфира и 12,2 г уксусного .ангидрида и нагревают 15-20 ми . при температуре 105-110°С. После охлалодени тёмнокрасный раствор выливают тонкой струей в 0,5 л во .ды. Затвердевшую массу извлекают этиловым эфиром, выт жку промывают водой.-и высушивают N82804. После удалени эфира остаток многократно экстрагируют петролейным эфиром (температура кипени 65- 80°С).Example I. 7.2 g of hippuric acid are mixed with 6 g of orthof ether and 12.2 g of acetic. Anhydride and heated for 15-20 mi. at a temperature of 105-110 ° C. After cooling, the dark red solution is poured in a thin stream of 0.5 liter. The solidified mass is extracted with ethyl ether, the extract is washed with water. And dried N82804. After removal of the ether, the residue is extracted several times with petroleum ether (boiling point 65-80 ° C).
Выделившиес при охлаждении кристаллы, слегка загр зненные Слюлой, промывают холодным метиловым спиртом. Выход 2,15 г. Дл анализа вещество перекристаллизозывают из петролейного эфира сThe crystals, which were lightly polluted by Sluloy, when they were cooled, were washed with cold methyl alcohol. Yield 2.15 g. For analysis, the substance is recrystallized from petroleum ether with
,Отв. редактор М. М. Акишин, Ed. editor M. M. Akishin
добавлением угл . При этом выпадает 2-фенил-4-этоксиметилен-оксазолинон-5 в виде бесцветных игол, имеющих температуру плавлени 95-96°С.by adding char. This releases 2-phenyl-4-ethoxymethylene-oxazolinone-5 in the form of colorless needles having a melting point of 95-96 ° C.
Пример П. Опыт провод т так же, как и в примере I. Затвердевшую под водой массу хорошо растирают с небольшим количеством холодного этилового спирта и отсасывают .Example P. The test was carried out in the same manner as in Example I. The mass which solidified under water was well ground with a small amount of cold ethyl alcohol and sucked off.
Предмет изобретени Способ получени 2-фенил-4-алкоксиметилен-оксазолинонов-5 , отличающийс тем, что гиппуровую кислоту конденсируют при нагревании с соответствующим ортомуравьиным эфиром в присутствии уксусного ангидрида.The subject of the invention is a process for the preparation of 2-phenyl-4-alkoxymethylene-oxazolinone-5, characterized in that the hippuric acid is condensed by heating with an appropriate ortoformate ether in the presence of acetic anhydride.
Редактор А. Е. НикитскийEditor A. E. Nikitsky
135135
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU146A SU76390A1 (en) | 1947-10-03 | 1947-10-03 | The method of obtaining 2-phenyl-4-alkohsimetilen-okeazolinone-5 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU146A SU76390A1 (en) | 1947-10-03 | 1947-10-03 | The method of obtaining 2-phenyl-4-alkohsimetilen-okeazolinone-5 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU76390A1 true SU76390A1 (en) | 1948-11-30 |
Family
ID=52744916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU146A SU76390A1 (en) | 1947-10-03 | 1947-10-03 | The method of obtaining 2-phenyl-4-alkohsimetilen-okeazolinone-5 |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU76390A1 (en) |
-
1947
- 1947-10-03 SU SU146A patent/SU76390A1/en active
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