SU664528A3 - Fungicide - Google Patents

Description

, one . . The invention relates to a chemical plant protection agent, specifically to a fungicidal agent based on triazole derivatives. The use of azole derivatives, for example, 1-L-butoxy- - (4-chlorophenyl) -ethyl-amidazole, is known as fungicides 1J. The prototype of the invention is fungicidal. The agent contains 1- (2,4-dichlorophenyl) -2- (1, 2,4-triazol-1-yl) - (2,4-dichlorobenzyl) -ethane as the active substance in the active substance 12, but the activity of the known means is insufficient. . The aim of the invention is to find a new fungicidal agent based on triazole derivatives with enhanced fungicidal activity. This is achieved by using an agent containing as active substance a triazole derivative of the formula CH — CH, where R is chlorine, chlorophenyl, chlorophenoxy and —1,2, or Their salts in an amount of 0.1-95 wt.%, The rest is an additive selected from groups of solid or liquid carriers; Forms of use of the usual: solutions, emulsions, suspensions, powders, pastes and granules. They are prepared by known methods - common in the preparation of preparative forms. pesticides. The process for preparing the compound of formula 1 is based on the interaction of 1-halogen-1-phenyl-2-triazolyl ethane derivatives with mercaptans. .Example. The method for producing 1- (4-chlorophenylthio) -l- (4-chlorop-4-biphenyl) -2- {1, 2, 4-triazol-1-yl) ethane nitrate,., 31.8 g (0, 1. mol) 1-chloro-1- {4-chloro-4-biphenylyl) -2- (1,2,4-triazol-1-yl) -ethane with 29 g (0.2 mol) of 4-chlorothiophenol and 29 g (0.21 mol) of potassium carbonate in 100 ml of acetone are heated in an hour, with reflux, the reaction | Then the filter is cozy and the filtrate is concentrated. The filter residue is extracted by repeated smegi-vaky with a water solution of NaQH and extracted by shaking with ether. The ether phase is dried over kaFry sulfate and concentrated. 34.4 g (81% of theory) and 1- (4-chlorophenylmercapto) -1- (4-chloro-4-biphenyl) -2- (1, 2,4-triazl-1-yl) -ethane are obtained, t pl. It was dissolved in chloroform, and bp MP of 98% nitric acid was added to crystallize. The Crystalline Product isolated at This was recrystallized from isopropanol. 38.2 g (90% of theory) of 1- (4-chloro-phenylthio nitrate) were obtained. ) -1-) 4-chloro-4-biphenyl) -2- (1,2,4-triazol-1-yl) -ethane, t. pl, 144 ° C (decomp.) .. Example 1. Test with Erj sipbe (protective action), -,,. , A solution of the existing vodvestva | 1 cucumber plants are harvested, having about 3 Leaves, up to; droplet formation. Then the plants; ; . Cucumber & for 54 hours, they are styled in depression, then they are inoculated with conidia of the fungus Etysipbe cichowaceapum and kept at a temperature of 23-24 ° C and a relative humidity of the air of about 75%, 12 days. After 12 days, the extent of damage to cucumber plants is determined. Herewith, 0% means no damage, 100% growth is completely destroyed, :: -. . :. .. V ;;. .. J. In tab. 1, the degree of injury of fellows with caviar was observed at the ends of the trajectory of active principle of 0.0005%. Table Continued table. 1 .I Example 3, Test PoEospfxieroi (for protective action). The young saplings of blonds, from 4 to 6 leaves in the ravevity stage, are sprayed with a solution of the active substance before dropping. Plants within 24 hours at a temperature and relative humidity of 70% are stored in a greenhouse. They are then inoculated with conidia of the powdery powdery PoEosplioiera € eucotHcha pathogen and left at a temperature of 21 ° C to 23 ° C and about 70% of the greenhouse air humidity in the greenhouse .. 10 days after inoculation; At this 0% - no damage, 100% of the plants are completely affected, In table. 2 shows the degree of time. marriages of blonds with powdery mildew at a concentration of the beginning of 0.0025%, :: Table 2

87

(known)

-.-..-, -,.-...-,.,

CH-CHz-N;

N

X NNOZ

(W-CH2-I- (I

NNKOH

f-CHz- J

Hno}

thirty

Example 4. Test p Tgb ttadium (protective actions).

The young sunflowers of the blony, which are in the stages of development from 4 to lateral, are sprayed with a solution of the action of the seeds, before the formation of drops. The plants are left for 24 hours at a temperature of 20 ° C and a relative humidity of 70% in the greenhouse.

They are then inoculated with an aqueous suspension of conidia of the driver Pirshi bloc TIjsictocMijm denolfiticorn and incubated for 18 hours at 18–20 s and 100% relative air in a humid chamber. Then the plants are re-kept for 14 days in a greenhouse.

After inoculation, the extent of damage to the seedlings is determined. In this case, 0% means no damage, 100% of the plants are completely affected.

In tab. Figure 3 shows the degree of damage to blonds by scab, depending on the concentration.

, T and l and c and 3 example 5. The test with mealy dew of breads (protective medical action). With a test circuit of the protective deist of VIA, one-year-old young plants of the nome variety AmseC are sprayed to the dew moisture with an active ingredient. After drying, the barley plants are powdered with spores of bruccinia votp hof oleV.

6

To test the therapeutic effect, young barley plants that have one Leaf after 48 hours after the inoculation are treated with the drug actually beginning when the infection is already developed.

After 6 days of stay of the plants at a temperature of 2l-220c and an air humidity of 80-90%, the plants are damaged by powdery mildew pustules. The degree of damage is expressed in% damage to untreated control plants. At the same time, 0% is the absence of a lesion and 100% is the extent of the lesion as in the untreated control.

The active principle is the more effective the less powdery mildew.

In tab. 4 shows the extent of the lesion of barley with powdery mildew at a concentration of active principle IO, 0025 wt.%,

GABlice 4

Degree%

Acting

protective and therapeutic action

100,100

unprocessed

 / Emergency) VcH-CH -i

he sng m: I

 so, Hf

.70.0 82.5

ScN, X llzOti) (Ngbestm) JQ „

C1

a- (Q) -CH-CH -N J

to : S

3.8OfO

fcH-CKr / J pro in "c 6f 113 48.8 0.0 U". 3 8.8 Formula 13 of the invention A fungicidal agent containing triazole derivative as an active ingredient, as well as an additive selected from the group of solid or liquid carriers, which is so that, in order to enhance the fungicidal activity, it contains, as triaol derivatives, compounds of the general formula Cn-HH-n I 8 where R is chlorine, hporpenyl, chlorophenoxy; p-If2, or their salts in the amount of 0.1-95 sec.%. Sources of information taken into account in the examination 1. Complicated application of Germany No. 2063857. Cl. 12 p. 9, 1971. The application for which a positive zeal was issued for the grant of a patent of the USSR 2414026, cl. A 01 N9 / 22, 1976.

.. --f