SU489326A3 - Method for preparing substituted 2-arylaminoimidazolines- (2) - Google Patents
Method for preparing substituted 2-arylaminoimidazolines- (2)Info
- Publication number
- SU489326A3 SU489326A3 SU1739515A SU1739515A SU489326A3 SU 489326 A3 SU489326 A3 SU 489326A3 SU 1739515 A SU1739515 A SU 1739515A SU 1739515 A SU1739515 A SU 1739515A SU 489326 A3 SU489326 A3 SU 489326A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- arylaminoimidazolines
- preparing substituted
- substituted
- preparing
- bromine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2237/00—Aspects relating to ceramic laminates or to joining of ceramic articles with other articles by heating
- C04B2237/30—Composition of layers of ceramic laminates or of ceramic or metallic articles to be joined by heating, e.g. Si substrates
- C04B2237/32—Ceramic
- C04B2237/36—Non-oxidic
- C04B2237/366—Aluminium nitride
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Description
npeflts ex изобретени 1, Способ получени замещенных вмииоимидазо;шнов -(2.) обшей формулы где Г J ч быть одинежовыми или различными и означают атом водорода, фтора, хлора, или брома, метильную или этильную группы, или их солей, отличающийс тем, что соединение общей формулы где RI RO имеют указанные значени , подвергают взаимодействию с галогениом общей формулы НаС - СН 2-f где Hat хлор, бром или йод, с последующим выделением целевого продукта в свободном состо нии или в виде сопи известными способами. 2.Способ по п. 1, отличаю,.щ и и с , тем, что взаимодействие провод т в присутствии органического растворител . 3.Способ по пп. 1и2, отличающийс тем, что взаимодействие провод т при 50-15О°С. 4.Способ по пп, 1-3, отличающийс тем,. что галогенид формулы 1П примен ют в избытке.npeflts ex of invention 1, a method for producing substituted vmioimidazo; shnov - (2.) general formulas where GJ are either single or different and denote a hydrogen atom, fluorine, chlorine or bromine, methyl or ethyl groups, or their salts, that a compound of the general formula where RI RO has the indicated meanings is reacted with halogeno of the general formula Na — CH 2 -f where Hat is chlorine, bromine or iodine, followed by isolation of the desired product in the free state or as copium by known methods. 2. The method according to claim 1, distinguishing between,., And and c, in that the reaction is carried out in the presence of an organic solvent. 3. Method according to paragraphs. 1 and 2, characterized in that the reaction is carried out at 50-15 ° C. 4. Method according to claims, 1-3, characterized in that. that the halide of formula 1P is used in excess.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712102733 DE2102733A1 (en) | 1971-01-21 | 1971-01-21 | 2-arylamino-2-imidazolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU489326A3 true SU489326A3 (en) | 1975-10-25 |
Family
ID=5796515
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1791184A SU420176A3 (en) | 1971-01-21 | 1972-01-19 | |
| SU1791185A SU433679A3 (en) | 1971-01-21 | 1972-01-19 | METHOD OF OBTAINING 2-ARYLAMINOIMIDAZOLINES- (2) |
| SU1739515A SU489326A3 (en) | 1971-01-21 | 1972-01-19 | Method for preparing substituted 2-arylaminoimidazolines- (2) |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1791184A SU420176A3 (en) | 1971-01-21 | 1972-01-19 | |
| SU1791185A SU433679A3 (en) | 1971-01-21 | 1972-01-19 | METHOD OF OBTAINING 2-ARYLAMINOIMIDAZOLINES- (2) |
Country Status (25)
| Country | Link |
|---|---|
| JP (4) | JPS5549576B1 (en) |
| AT (2) | AT311335B (en) |
| AU (1) | AU456491B2 (en) |
| BE (1) | BE778298A (en) |
| BG (4) | BG20794A3 (en) |
| CA (1) | CA982593A (en) |
| CH (2) | CH566318A5 (en) |
| CS (2) | CS178093B2 (en) |
| DD (1) | DD95843A5 (en) |
| DK (1) | DK128779B (en) |
| ES (2) | ES399003A1 (en) |
| FI (1) | FI54296C (en) |
| FR (1) | FR2122580B1 (en) |
| GB (1) | GB1373276A (en) |
| HU (1) | HU163085B (en) |
| IE (1) | IE36643B1 (en) |
| IL (1) | IL38593A (en) |
| NL (1) | NL7200854A (en) |
| NO (1) | NO128570B (en) |
| PH (1) | PH11404A (en) |
| PL (2) | PL86654B1 (en) |
| RO (1) | RO62483A (en) |
| SU (3) | SU420176A3 (en) |
| YU (1) | YU34999B (en) |
| ZA (1) | ZA72409B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2308883C3 (en) * | 1973-02-23 | 1978-05-24 | C.H. Boehringer Sohn, 6507 Ingelheim | 2-Phenylamino-thienylmethyl-imidazoline- (2), process for the preparation of the same and medicaments containing them |
| DE2636732A1 (en) * | 1976-08-14 | 1978-02-16 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
| DE2831671A1 (en) * | 1978-07-19 | 1980-02-07 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
| FI65428C (en) * | 1978-12-12 | 1984-05-10 | Luso Farmaco Inst | DERIVATIVES FOR THE FRAMEWORK OF PHARMACOLOGICAL PROPERTIES OF 2-PHENYLAMINO-IMIDAZOLE (2) |
| JPS58173671U (en) * | 1982-05-14 | 1983-11-19 | 三菱電機株式会社 | Elevator cab lighting system |
| FR2919608B1 (en) * | 2007-08-01 | 2012-10-05 | Univ Rennes | IMIDAZOLON DERIVATIVES, PREPARATION METHOD AND BIOLOGICAL APPLICATIONS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759125A (en) * | 1969-11-19 | 1971-05-18 | Boehringer Sohn Ingelheim | NEW N-ALLYL-2-ARYLAMINO-IMIDAZOLINES- (2) SUBSTITUTES AND METHODS FOR MAKING THEM |
-
1972
- 1972-01-17 DD DD160373A patent/DD95843A5/xx unknown
- 1972-01-18 BG BG019498A patent/BG20794A3/en unknown
- 1972-01-18 BG BG020646A patent/BG18868A3/en unknown
- 1972-01-18 CH CH72272A patent/CH566318A5/xx not_active IP Right Cessation
- 1972-01-18 BG BG020647A patent/BG19160A3/en unknown
- 1972-01-18 BG BG020648A patent/BG19161A3/en unknown
- 1972-01-18 CH CH747775A patent/CH566319A5/xx not_active IP Right Cessation
- 1972-01-19 SU SU1791184A patent/SU420176A3/ru active
- 1972-01-19 JP JP755372A patent/JPS5549576B1/ja active Pending
- 1972-01-19 SU SU1791185A patent/SU433679A3/en active
- 1972-01-19 ES ES399003A patent/ES399003A1/en not_active Expired
- 1972-01-19 HU HUBO1346A patent/HU163085B/hu unknown
- 1972-01-19 YU YU134/72A patent/YU34999B/en unknown
- 1972-01-19 RO RO7200069449A patent/RO62483A/en unknown
- 1972-01-19 SU SU1739515A patent/SU489326A3/en active
- 1972-01-20 AT AT46872A patent/AT311335B/en not_active IP Right Cessation
- 1972-01-20 BE BE778298A patent/BE778298A/en not_active IP Right Cessation
- 1972-01-20 FI FI134/72A patent/FI54296C/en active
- 1972-01-20 DK DK29972AA patent/DK128779B/en unknown
- 1972-01-20 PL PL1972176412A patent/PL86654B1/en unknown
- 1972-01-20 CA CA132,812A patent/CA982593A/en not_active Expired
- 1972-01-20 IL IL38593A patent/IL38593A/en unknown
- 1972-01-20 AT AT1080372A patent/AT316546B/en not_active IP Right Cessation
- 1972-01-20 NO NO00130/72A patent/NO128570B/no unknown
- 1972-01-20 PL PL1972153005A patent/PL83112B1/en unknown
- 1972-01-20 PH PH13216A patent/PH11404A/en unknown
- 1972-01-20 AU AU38108/72A patent/AU456491B2/en not_active Expired
- 1972-01-20 ZA ZA720409A patent/ZA72409B/en unknown
- 1972-01-20 CS CS380A patent/CS178093B2/cs unknown
- 1972-01-20 CS CS1987A patent/CS178097B2/cs unknown
- 1972-01-21 FR FR7202055A patent/FR2122580B1/fr not_active Expired
- 1972-01-21 GB GB303172A patent/GB1373276A/en not_active Expired
- 1972-01-21 NL NL7200854A patent/NL7200854A/xx not_active Application Discontinuation
- 1972-01-21 IE IE84/72A patent/IE36643B1/en unknown
-
1973
- 1973-10-18 ES ES419739A patent/ES419739A1/en not_active Expired
-
1979
- 1979-10-02 JP JP12721779A patent/JPS5547680A/en active Granted
- 1979-10-02 JP JP12721579A patent/JPS5547661A/en active Granted
- 1979-10-02 JP JP12721679A patent/JPS5547662A/en active Granted
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