SU448864A1 - The method of obtaining antilles to the Australian antigen - Google Patents

The method of obtaining antilles to the Australian antigen

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Publication number
SU448864A1
SU448864A1 SU1932651A SU1932651A SU448864A1 SU 448864 A1 SU448864 A1 SU 448864A1 SU 1932651 A SU1932651 A SU 1932651A SU 1932651 A SU1932651 A SU 1932651A SU 448864 A1 SU448864 A1 SU 448864A1
Authority
SU
USSR - Soviet Union
Prior art keywords
obtaining
antilles
australian antigen
australian
antigen
Prior art date
Application number
SU1932651A
Other languages
Russian (ru)
Inventor
Анатолий Федорович Блюгер
Елена Карловна Яворковская
Original Assignee
Рижский Медицинский Институт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рижский Медицинский Институт filed Critical Рижский Медицинский Институт
Priority to SU1932651A priority Critical patent/SU448864A1/en
Application granted granted Critical
Publication of SU448864A1 publication Critical patent/SU448864A1/en

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Description

1one

Изобретение относитс  к медицине.This invention relates to medicine.

Известен способ получени  антител к австралийскому антигену путем центрифугировани  сыворотки крови, содержащей антитела , и использованием в качестве исходного материала крови доноров.A method is known for producing antibodies to an Australian antigen by centrifuging serum containing antibodies and using donor blood as the starting material.

Однако известный способ обеспечивает невысокий выход препарата.However, the known method provides a low yield of the drug.

Цель изобретени  - увеличение выхода препарата.The purpose of the invention is to increase the yield of the drug.

Это достигаетс  тем, что по предлагаемому способу в качестве исходного материала используют кровь от трупов людей с гематологическими заболевани ми после многих гематрансфузий , вз тую не позднее чем через шесть часов после гибели.This is achieved in that according to the proposed method, blood from the corpses of people with hematological diseases after many hematransfusions, taken no later than six hours after death, is used as the starting material.

Способ получени  антител к австралийскому антигену заключаетс  в следующем.The method for producing antibodies to the Australian antigen is as follows.

В первые щесть часов после смерти больного заготавливают его кровь дл  получени  антител к австралийскому антигену.In the first few hours after the death of the patient, his blood is harvested to produce antibodies to the Australian antigen.

Очищенную сыворотку получают центрифугированием с чередованием процесса отстаивани .Purified serum is obtained by centrifugation alternating the process of settling.

Центрифугирование производ т 2-3 раза по 10-15 мин каждое, затем отстаивают в течение 20-24 час.Centrifugation is performed 2-3 times for 10-15 minutes each, then stand for 20-24 hours.

Дл  достижени  рабочего титра антител заготовленную сыворотку, содержащую антитела к австралийскому антигену, подвергают лиофилизации или концентрированию полимерами , например поливинилпиролидоном.In order to achieve a working antibody titer, the prepared serum containing antibodies to the Australian antigen is subjected to lyophilization or concentration with polymers, for example polyvinylpyrrolidone.

При употреблении сыворотки ее раствор ют в дистиллированной воде до рабочего титра антител к австралийскому антигену.When consumed, serum is dissolved in distilled water until the working titer of antibodies to the Australian antigen.

Предмет изобретени Subject invention

Способ получени  антител к австралийскому антигену путем выделени  целевого продукта из сыворотки крови, отличающийс   тем, что, с целью увеличени  выхода препарата , в качестве исходного материала используют кровь от трупов людей с гематологическими заболевани ми после многих гематрансфузий , вз тую не позднее чем через шесть часов после гибели.A method of obtaining antibodies to an Australian antigen by isolating a target product from blood serum, characterized in that, in order to increase the yield of the drug, blood from the corpses of people with hematological diseases after many hematransfusions taken no later than six hours after death.

SU1932651A 1973-06-29 1973-06-29 The method of obtaining antilles to the Australian antigen SU448864A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU1932651A SU448864A1 (en) 1973-06-29 1973-06-29 The method of obtaining antilles to the Australian antigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU1932651A SU448864A1 (en) 1973-06-29 1973-06-29 The method of obtaining antilles to the Australian antigen

Publications (1)

Publication Number Publication Date
SU448864A1 true SU448864A1 (en) 1974-11-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU1932651A SU448864A1 (en) 1973-06-29 1973-06-29 The method of obtaining antilles to the Australian antigen

Country Status (1)

Country Link
SU (1) SU448864A1 (en)

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