SU384818A1 - - Google Patents

Info

Publication number

SU384818A1

SU384818A1 SU1377158A SU1377158A SU384818A1 SU 384818 A1 SU384818 A1 SU 384818A1 SU 1377158 A SU1377158 A SU 1377158A SU 1377158 A SU1377158 A SU 1377158A SU 384818 A1 SU384818 A1 SU 384818A1

Authority

SU

USSR - Soviet Union

Prior art keywords

target product

yield

hydrochloric acid

aromatic

residue

Prior art date

1969-11-03

Links

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• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 7
• HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
• 238000000034 method Methods 0.000 description 5
• PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 4
• 150000004982 aromatic amines Chemical class 0.000 description 4
• HTKXRTUKPXEALT-UHFFFAOYSA-N 3-bromo-2h-indazole Chemical compound C1=CC=CC2=C(Br)NN=C21 HTKXRTUKPXEALT-UHFFFAOYSA-N 0.000 description 3
• 125000003118 aryl group Chemical group 0.000 description 3
• BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 description 2
• 238000006243 chemical reaction Methods 0.000 description 2
• 150000001875 compounds Chemical class 0.000 description 2
• 238000007796 conventional method Methods 0.000 description 2
• 229910052739 hydrogen Inorganic materials 0.000 description 2
• 239000001257 hydrogen Substances 0.000 description 2
• 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
• MWKZLAQDGRSBHS-UHFFFAOYSA-N n-phenyl-1h-indazol-3-amine Chemical compound N=1NC2=CC=CC=C2C=1NC1=CC=CC=C1 MWKZLAQDGRSBHS-UHFFFAOYSA-N 0.000 description 2
• 235000011121 sodium hydroxide Nutrition 0.000 description 2
• 238000010186 staining Methods 0.000 description 2
• 238000003786 synthesis reaction Methods 0.000 description 2
• QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 1
• WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
• 230000001476 alcoholic effect Effects 0.000 description 1
• 125000000217 alkyl group Chemical group 0.000 description 1
• 239000003708 ampul Substances 0.000 description 1
• MMCPOSDMTGQNKG-UHFFFAOYSA-N anilinium chloride Chemical compound Cl.NC1=CC=CC=C1 MMCPOSDMTGQNKG-UHFFFAOYSA-N 0.000 description 1
• 125000005264 aryl amine group Chemical group 0.000 description 1
• 230000015572 biosynthetic process Effects 0.000 description 1
• 239000011521 glass Substances 0.000 description 1
• 238000010438 heat treatment Methods 0.000 description 1
• 125000001841 imino group Chemical group [H]N=* 0.000 description 1
• 239000000543 intermediate Substances 0.000 description 1
• 238000002955 isolation Methods 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 238000002360 preparation method Methods 0.000 description 1
• 238000001953 recrystallisation Methods 0.000 description 1
• 229910052709 silver Inorganic materials 0.000 description 1
• 239000004332 silver Substances 0.000 description 1
• 239000007858 starting material Substances 0.000 description 1
• HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 description 1