SU1599082A1 - Method of producing carbon-mineral sorbent - Google Patents

Abstract

The invention relates to methods for producing sorbents and permits an increase in the sorption activity for bilirubin. The method includes the deposition of aluminum hydroxide gel in the presence of coarse silica gel containing 1-5 wt.% Carbon, with a mass ratio of aluminum hydroxide to silica gel 1: (1-4), aging the gel, separating the precipitate and washing it with a solid-water ratio 1 : (20-40). 1 tab.

Description

The invention relates to methods for the preparation of sorbents and can be used in the manufacture of adsorbents for medical and biomedical purposes.

The purpose of the invention is to increase the sorption activity for bilinubinus

The method is carried out as follows.

In 100 g of a 10% aqueous solution of AlClj 5.85 g of ground large is introduced. porous silica gel, a CLAIM containing 4 wt.% coal, and a 12.5% ammonium hydroxide solution is added and, with intensive movement to pH 8 °, the resulting product ages under the mother liquor for 2 hours. The precipitate is separated from the mother liquor, condensed on the filter and washed

175 ml of water In the final product, the mass ratio of A1 (OH): carbon-silica gel is 1: 1. The sorption activity of the resulting carbon-mineral sorbent for bilirubin is 31 mg / g.

To determine the sorption stock. A series of bilirubin solutions of different concentrations was prepared and measured at an optical density on a KFK-2 photocolorimeter at i 440 nm.

Preliminarily, the solids content was carried out by the gravimetric method by calcining a sample of the precipitate at 800–900 s to a constant weight.

Determination of the sorption activity for bilirubin was carried out as follows: the tubes were poured by

ate

00 HS

10 ml of bilirubin solution of varying concentration, after which 5 ml of the suspension of the obtained coal-and-mineral sorbent with a known solid content were added to each of the tubes. bilirubin "For the study used reference lyophilized ruby company LaCheMa ..

The table presents data on the ratio of the components of the sorbent, the washing conditions and the sorption activity of the obtained bilirubin samples.

Replacing the coal component with the coal mine contributes to a more uniform structuring of the Al (OH) j gel due to the partial polycondensation interaction of the hydrophilic groups of the carbon gel with hydroxyl groups of aluminum hydrogel. This leads to a sorbent with an optimal ratio of hydrophobic-hydrophilic properties. The bilirubin molecule, being a typical polar sorbate, actively interacts with the obtained mineral-mineral sorbent. The amount of bilirubin absorbed by the sorbent is much higher than the value of dp of separately taken A1 (OH) gel. and large pore carbon dioxide (5.2 mg / g and 3.9 mg / g, respectively).

The technical and economic efficiency of the proposed method is expressed in improving the quality of the final product due to an increase in bilirubin sorption activity by a factor of 3-6 compared with the known method

Claims (1)

Invention Formula A method for producing a carbon-mineral sorbent, which includes introducing carbon-containing material into an aluminum salt solution, introducing an alkali before precipitating an aluminum hydroxide gel, aging, separating the precipitate and washing it, characterized in that sorption activity for bilirubin; as a carbon-containing material, a large-pore reagent gel containing 1–5 wt. carbon precipitation lead to mass The ratios of aluminum hydroxide: carbon-containing silica gel in the product are 1: 1-4, and the precipitate is washed with water at a solid-liquid ratio of 1: 20-40.