SMT201500222B - Peptidi leganti il recettore del fattore di crescita 1 insulino-simile - Google Patents

Peptidi leganti il recettore del fattore di crescita 1 insulino-simile

Info

Publication number
SMT201500222B
SMT201500222B SM201500222T SM201500222T SMT201500222B SM T201500222 B SMT201500222 B SM T201500222B SM 201500222 T SM201500222 T SM 201500222T SM 201500222 T SM201500222 T SM 201500222T SM T201500222 B SMT201500222 B SM T201500222B
Authority
SM
San Marino
Prior art keywords
insulin
receptor
growth factor
binding peptide
peptide
Prior art date
Application number
SM201500222T
Other languages
English (en)
Italian (it)
Inventor
Michael Diem
Karen O'neil
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of SMT201500222B publication Critical patent/SMT201500222B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SM201500222T 2010-05-27 2015-09-22 Peptidi leganti il recettore del fattore di crescita 1 insulino-simile SMT201500222B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34893710P 2010-05-27 2010-05-27
PCT/US2011/037904 WO2011150061A1 (en) 2010-05-27 2011-05-25 Insulin-like growth factor 1 receptor binding peptides

Publications (1)

Publication Number Publication Date
SMT201500222B true SMT201500222B (it) 2015-10-30

Family

ID=45004356

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500222T SMT201500222B (it) 2010-05-27 2015-09-22 Peptidi leganti il recettore del fattore di crescita 1 insulino-simile

Country Status (28)

Country Link
US (1) US8415306B2 (xx)
EP (1) EP2575846B1 (xx)
JP (1) JP5864556B2 (xx)
KR (1) KR101898502B1 (xx)
CN (1) CN103025341B (xx)
AU (1) AU2011258301B2 (xx)
BR (1) BR112012030084B1 (xx)
CA (1) CA2800744C (xx)
CY (1) CY1116757T1 (xx)
DK (1) DK2575846T3 (xx)
EA (1) EA023541B1 (xx)
ES (1) ES2550040T3 (xx)
HK (1) HK1183234A1 (xx)
HR (1) HRP20151084T1 (xx)
HU (1) HUE026269T2 (xx)
IL (1) IL223030A (xx)
ME (1) ME02206B (xx)
MX (1) MX337134B (xx)
NZ (1) NZ603611A (xx)
PL (1) PL2575846T3 (xx)
PT (1) PT2575846E (xx)
RS (1) RS54278B1 (xx)
SG (1) SG186068A1 (xx)
SI (1) SI2575846T1 (xx)
SM (1) SMT201500222B (xx)
UA (1) UA107596C2 (xx)
WO (1) WO2011150061A1 (xx)
ZA (1) ZA201209689B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3114140B1 (en) 2014-03-06 2019-02-27 National Research Council of Canada Insulin-like growth factor 1 receptor -specific antibodies and uses thereof
KR102355308B1 (ko) 2014-03-06 2022-01-24 내셔날 리서치 카운실 오브 캐나다 인슐린-유사 성장 인자 1 수용체-특이적 항체 및 그의 용도
PE20161311A1 (es) 2014-03-06 2016-11-25 Nat Res Council Canada Anticuerpos especificos del receptor del factor 1 de crecimiento similar a la insulina y usos de los mismos.
MY197348A (en) 2015-12-21 2023-06-14 Brainon Inc A composition for improving memory, learning ability, and cognitive ability
KR101706296B1 (ko) 2015-12-21 2017-02-13 주식회사 브레인온 기억력, 학습력, 인지력 향상용 조성물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US6329508B1 (en) 1989-09-07 2001-12-11 Alkermes, Inc. Transferrin receptor reactive chimeric antibodies
JPH06228199A (ja) * 1992-11-27 1994-08-16 Takeda Chem Ind Ltd 血液脳関門通過可能なペプチド結合体
EP1006184A1 (en) * 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
US20100293669A2 (en) * 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
US20090087878A9 (en) 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
AU6607100A (en) 1999-07-23 2001-02-13 Regents Of The University Of California, The Anti-growth factor receptor avidin fusion proteins as universal vectors for drugdelivery
JP4027663B2 (ja) 1999-10-04 2007-12-26 ネクター セラピューティックス エイエル,コーポレイション ポリマー安定化神経ペプチド
US20020009491A1 (en) 2000-02-14 2002-01-24 Rothbard Jonathan B. Compositions and methods for enhancing drug delivery across biological membranes and tissues
KR20030036835A (ko) * 2000-09-26 2003-05-09 제넨테크, 인크. Ige 수용체 길항제
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
EP1494712A4 (en) * 2002-03-26 2006-06-14 Centocor Inc MULTIPLE SCLEROSIS RELATED PROTEINS, COMPOSITIONS, PROCESSES AND APPLICATIONS DERIVED FROM IMMUNOGLOBULIN
US7388079B2 (en) 2002-11-27 2008-06-17 The Regents Of The University Of California Delivery of pharmaceutical agents via the human insulin receptor
US20050026823A1 (en) 2003-06-20 2005-02-03 Biomarin Pharmaceutical Inc. Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues
US8017151B2 (en) 2004-09-07 2011-09-13 Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center Amphiphilic polymer-protein conjugates and methods of use thereof
CA2611149A1 (en) * 2005-06-15 2006-12-28 Schering Corporation Anti-igf1r antibody formulations
US8053569B2 (en) * 2005-10-07 2011-11-08 Armagen Technologies, Inc. Nucleic acids encoding and methods of producing fusion proteins
WO2008143679A2 (en) * 2006-06-01 2008-11-27 Verenium Corporation Nucleic acids and proteins and methods for making and using them
EP2197490A2 (en) * 2007-08-28 2010-06-23 Biogen Idec MA, Inc. Compositions that bind multiple epitopes of igf-1r
ES2564523T3 (es) 2007-12-19 2016-03-23 Janssen Biotech, Inc. Diseño y generación de bibliotecas de presentación en fago por pIX de novo humanas mediante fusión con pIX o pVII, vectores, anticuerpos y métodos

Also Published As

Publication number Publication date
UA107596C2 (uk) 2015-01-26
CN103025341A (zh) 2013-04-03
IL223030A0 (en) 2013-02-03
RS54278B1 (en) 2016-02-29
US20110294748A1 (en) 2011-12-01
EP2575846A1 (en) 2013-04-10
MX2012013710A (es) 2013-05-20
HK1183234A1 (zh) 2013-12-20
MX337134B (es) 2016-02-12
CN103025341B (zh) 2015-07-22
CA2800744C (en) 2018-09-04
CA2800744A1 (en) 2011-12-01
JP5864556B2 (ja) 2016-02-17
WO2011150061A1 (en) 2011-12-01
HUE026269T2 (en) 2016-06-28
AU2011258301A1 (en) 2012-12-06
SG186068A1 (en) 2013-01-30
EP2575846A4 (en) 2013-12-11
EA023541B1 (ru) 2016-06-30
PT2575846E (pt) 2015-09-16
PL2575846T3 (pl) 2015-12-31
CY1116757T1 (el) 2017-03-15
KR20130111237A (ko) 2013-10-10
ME02206B (me) 2016-02-20
SI2575846T1 (sl) 2015-09-30
NZ603611A (en) 2014-12-24
EP2575846B1 (en) 2015-07-15
US8415306B2 (en) 2013-04-09
IL223030A (en) 2016-11-30
BR112012030084A2 (pt) 2017-06-20
KR101898502B1 (ko) 2018-09-13
EA201291416A1 (ru) 2013-06-28
BR112012030084B1 (pt) 2020-04-14
ES2550040T3 (es) 2015-11-04
HRP20151084T1 (hr) 2015-11-06
ZA201209689B (en) 2014-05-28
AU2011258301B2 (en) 2013-11-21
DK2575846T3 (en) 2015-08-10
JP2013534811A (ja) 2013-09-09

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