SMT201500139B - Ligandi radiomarcati a base di fenilimidazolo - Google Patents

Ligandi radiomarcati a base di fenilimidazolo

Info

Publication number
SMT201500139B
SMT201500139B SM201500139T SM201500139T SMT201500139B SM T201500139 B SMT201500139 B SM T201500139B SM 201500139 T SM201500139 T SM 201500139T SM 201500139 T SM201500139 T SM 201500139T SM T201500139 B SMT201500139 B SM T201500139B
Authority
SM
San Marino
Prior art keywords
phenylimidazole
radiolabelled ligands
radiolabelled
ligands
based radiolabelled
Prior art date
Application number
SM201500139T
Other languages
English (en)
Inventor
Jan Kehler
Benny Bang-Andersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of SMT201500139B publication Critical patent/SMT201500139B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SM201500139T 2010-11-10 2015-06-16 Ligandi radiomarcati a base di fenilimidazolo SMT201500139B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41193410P 2010-11-10 2010-11-10
DKPA201001023 2010-11-10
PCT/DK2011/000132 WO2012062319A1 (en) 2010-11-10 2011-11-10 Radiolabelled phenylimidazole-based ligands

Publications (1)

Publication Number Publication Date
SMT201500139B true SMT201500139B (it) 2015-09-07

Family

ID=45098760

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500139T SMT201500139B (it) 2010-11-10 2015-06-16 Ligandi radiomarcati a base di fenilimidazolo

Country Status (19)

Country Link
US (1) US8592449B1 (it)
EP (1) EP2637704B9 (it)
JP (1) JP5820887B2 (it)
CN (1) CN103732260B (it)
AU (1) AU2011328598B2 (it)
CA (1) CA2817385A1 (it)
DK (1) DK2637704T5 (it)
ES (1) ES2539464T3 (it)
HK (1) HK1189498A1 (it)
HR (1) HRP20150560T2 (it)
HU (1) HUE025511T2 (it)
ME (1) ME02145B (it)
PL (1) PL2637704T3 (it)
PT (1) PT2637704E (it)
RS (1) RS54039B1 (it)
SG (1) SG190686A1 (it)
SI (1) SI2637704T1 (it)
SM (1) SMT201500139B (it)
WO (1) WO2012062319A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790203B2 (en) 2012-11-26 2017-10-17 Abbvie Inc. Inhibitor compounds of phosphodiesterase type 10A
US20150313884A1 (en) 2013-01-15 2015-11-05 Novartis Ag Use of alpha 7 nicotinic acetylcholine receptor agonists
KR101879920B1 (ko) * 2013-01-15 2018-07-18 노파르티스 아게 알파 7 니코틴성 아세틸콜린 수용체 작용물질의 용도
CA2899781A1 (en) * 2013-01-31 2014-08-07 F.Hoffmann-La Roche Ag Radiolabeled compounds
TW202031250A (zh) 2018-11-06 2020-09-01 丹麥商H 朗德貝克公司 用於治療負性症狀和認知損傷之pde10a抑制劑

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0425548D0 (en) 2004-11-19 2004-12-22 Glaxo Group Ltd Radiolabelled ligands
WO2006075226A1 (en) 2005-01-13 2006-07-20 Pfizer Products Inc. 11c-labeled benzyl-lactam compounds and their use as imaging agents
WO2008020302A2 (en) 2006-08-17 2008-02-21 Pfizer Products Inc. Heteroaromatic quinoline-based compounds as phosphodiesterase (pde) inhibitors
EP2036578A1 (en) 2007-09-13 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Diagnostic agents for positron emission imaging using F-18 radio labeled amino-alcohols
TWI501965B (zh) * 2008-06-20 2015-10-01 Lundbeck & Co As H 作為pde10a酵素抑制劑之新穎苯基咪唑衍生物
WO2010097367A1 (en) 2009-02-24 2010-09-02 Janssen Pharmaceutica Nv Radiolabelled pde10 ligands

Also Published As

Publication number Publication date
WO2012062319A1 (en) 2012-05-18
EP2637704A1 (en) 2013-09-18
US8592449B1 (en) 2013-11-26
PT2637704E (pt) 2015-07-21
CN103732260B (zh) 2018-08-10
EP2637704B1 (en) 2015-03-25
JP2013543851A (ja) 2013-12-09
EP2637704B9 (en) 2015-08-05
HRP20150560T1 (en) 2015-07-03
SG190686A1 (en) 2013-07-31
HK1189498A1 (en) 2014-06-13
DK2637704T5 (en) 2015-09-21
PL2637704T4 (pl) 2015-08-31
DK2637704T3 (da) 2015-06-22
AU2011328598B2 (en) 2016-04-21
SI2637704T1 (sl) 2015-07-31
RS54039B1 (en) 2015-10-30
HUE025511T2 (en) 2016-04-28
AU2011328598A1 (en) 2013-05-30
CA2817385A1 (en) 2012-05-18
US20130303770A1 (en) 2013-11-14
ME02145B (me) 2015-10-20
PL2637704T3 (pl) 2015-08-31
HRP20150560T2 (hr) 2015-11-20
CN103732260A (zh) 2014-04-16
ES2539464T3 (es) 2015-07-01
JP5820887B2 (ja) 2015-11-24

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