SK76293A3 - Dimethylester of 1,4-dihydropyridine-3,5-dikarboxylic acid, process for its preparation and its pharmaceutical application - Google Patents

Dimethylester of 1,4-dihydropyridine-3,5-dikarboxylic acid, process for its preparation and its pharmaceutical application Download PDF

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Publication number
SK76293A3
SK76293A3 SK762-93A SK76293A SK76293A3 SK 76293 A3 SK76293 A3 SK 76293A3 SK 76293 A SK76293 A SK 76293A SK 76293 A3 SK76293 A3 SK 76293A3
Authority
SK
Slovakia
Prior art keywords
chloro
acid
methyl ester
dimethyl
dihydropyridine
Prior art date
Application number
SK762-93A
Other languages
English (en)
Slovak (sk)
Inventor
Otto Behner
Hartmund Wollweber
Bruno Rosen
Siegfried Zaiss
Siegfried Goldmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SK76293A3 publication Critical patent/SK76293A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
SK762-93A 1992-07-20 1993-07-19 Dimethylester of 1,4-dihydropyridine-3,5-dikarboxylic acid, process for its preparation and its pharmaceutical application SK76293A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4223867A DE4223867A1 (de) 1992-07-20 1992-07-20 Spezieller 1,4-Dihydropyridin-3,5-dicarbonsäureester, Verfahren zu seiner Herstellung und seine pharmazeutische Verwendung

Publications (1)

Publication Number Publication Date
SK76293A3 true SK76293A3 (en) 1994-07-06

Family

ID=6463655

Family Applications (1)

Application Number Title Priority Date Filing Date
SK762-93A SK76293A3 (en) 1992-07-20 1993-07-19 Dimethylester of 1,4-dihydropyridine-3,5-dikarboxylic acid, process for its preparation and its pharmaceutical application

Country Status (16)

Country Link
US (1) US5559139A (fr)
EP (1) EP0581079A1 (fr)
JP (1) JPH06179654A (fr)
KR (1) KR940002223A (fr)
CN (1) CN1085548A (fr)
AU (1) AU4164693A (fr)
CA (1) CA2100707A1 (fr)
CZ (1) CZ141593A3 (fr)
DE (1) DE4223867A1 (fr)
FI (1) FI933255A (fr)
HU (1) HU9302077D0 (fr)
IL (1) IL106369A0 (fr)
MX (1) MX9304119A (fr)
PL (1) PL299713A1 (fr)
SK (1) SK76293A3 (fr)
ZA (1) ZA935191B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044316A (zh) * 2013-01-23 2013-04-17 石家庄学院 一种以咪唑离子液体为催化剂制备1,4-二氢吡啶的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
US3883543A (en) * 1969-05-10 1975-05-13 Bayer Ag N-alkyl-1,4-dihydropyridines
DE2210667A1 (de) * 1972-03-06 1973-09-20 Bayer Ag Kondensiert aromatisch substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3956341A (en) * 1974-02-21 1976-05-11 Smithkline Corporation 1,3,5-Tricarbo-1,4-dihydropyridines
US4975440A (en) * 1984-09-28 1990-12-04 Byk Gulden Lomberg Chemische Fabrik Gmbh Optically-active 1,4-dihydropyridine
US4780538A (en) * 1986-02-12 1988-10-25 Merck & Co., Inc. Process for 1,4-dihydropyridine compounds using a titanamine catalyst
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung
DE4200714A1 (de) * 1992-01-14 1993-07-15 Bayer Ag Spezieller 1,4-dihydropyridin-3,5-dicarbonsaeureester, verfahren zu seiner herstellung und seine pharmazeutische verwendung

Also Published As

Publication number Publication date
CA2100707A1 (fr) 1994-01-21
FI933255A0 (fi) 1993-07-16
AU4164693A (en) 1994-01-27
HU9302077D0 (en) 1993-10-28
FI933255A (fi) 1994-01-21
PL299713A1 (en) 1994-03-21
US5559139A (en) 1996-09-24
IL106369A0 (en) 1993-11-15
ZA935191B (en) 1994-03-02
CN1085548A (zh) 1994-04-20
JPH06179654A (ja) 1994-06-28
DE4223867A1 (de) 1994-01-27
EP0581079A1 (fr) 1994-02-02
CZ141593A3 (en) 1994-03-16
KR940002223A (ko) 1994-02-16
MX9304119A (es) 1994-02-28

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