SK62297A3 - Production of variant nisin - Google Patents

Production of variant nisin Download PDF

Info

Publication number
SK62297A3
SK62297A3 SK622-97A SK62297A SK62297A3 SK 62297 A3 SK62297 A3 SK 62297A3 SK 62297 A SK62297 A SK 62297A SK 62297 A3 SK62297 A3 SK 62297A3
Authority
SK
Slovakia
Prior art keywords
nisin
gene
nisa
variant
nisa gene
Prior art date
Application number
SK622-97A
Other languages
English (en)
Slovak (sk)
Inventor
Michael J Gasson
Helen M Dodd
Original Assignee
Inst Of Food Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Of Food Research filed Critical Inst Of Food Research
Publication of SK62297A3 publication Critical patent/SK62297A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Holo Graphy (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK622-97A 1994-11-19 1995-11-20 Production of variant nisin SK62297A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9423404A GB9423404D0 (en) 1994-11-19 1994-11-19 Production of nisin
PCT/GB1995/002699 WO1996016180A1 (en) 1994-11-19 1995-11-20 Production of variant nisin

Publications (1)

Publication Number Publication Date
SK62297A3 true SK62297A3 (en) 1997-12-10

Family

ID=10764691

Family Applications (1)

Application Number Title Priority Date Filing Date
SK622-97A SK62297A3 (en) 1994-11-19 1995-11-20 Production of variant nisin

Country Status (19)

Country Link
US (1) US6448034B1 (no)
EP (1) EP0793727B1 (no)
JP (1) JPH11500604A (no)
KR (1) KR970707290A (no)
CN (1) CN1085249C (no)
AT (1) ATE292686T1 (no)
AU (1) AU708788B2 (no)
BR (1) BR9510454A (no)
CA (1) CA2205204A1 (no)
CZ (1) CZ152197A3 (no)
DE (1) DE69534133T2 (no)
FI (1) FI972100A (no)
GB (1) GB9423404D0 (no)
HU (1) HUT77421A (no)
NO (1) NO972277L (no)
NZ (1) NZ295425A (no)
PL (1) PL320328A1 (no)
SK (1) SK62297A3 (no)
WO (1) WO1996016180A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861275A (en) * 1995-09-28 1999-01-19 The University Of Maryland Lantibiotic mutants and chimeras of enhanced stability and activity, leader sequences therefor, genes encoding the same, and methods of producing and using the same
US7034113B2 (en) * 2002-02-22 2006-04-25 Paradigm Diagnostics, Llc Bacteriocin-metal complexes in the detection of pathogens and other biological analytes
US6861236B2 (en) 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way
AP2005003346A0 (en) * 2002-12-10 2005-06-30 Biosynexus Inc Topical anti-infective formulations
WO2007014372A2 (en) * 2005-07-28 2007-02-01 Biosynexus Incorporated Compositions and methods for treating bacteria
JP2009526069A (ja) * 2006-02-08 2009-07-16 バイオシネクサス インコーポレーティッド 細菌胞子の中和
AU2013226402B2 (en) 2012-02-27 2017-05-18 Oragenics, Inc. Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
CN110627880B (zh) * 2018-06-25 2024-03-19 武汉合生科技有限公司 分离的多肽及其应用
US20220240529A1 (en) 2019-05-31 2022-08-04 Chr. Hansen A/S Composition comprising lactococcus, methods and products thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137869B1 (en) * 1983-09-06 1993-04-14 Microlife Technics, Inc. Derived nisin producing microorganisms, method of production and use and products obtained thereby
EP0579730B1 (en) * 1991-04-11 2003-02-26 Stichting Nederlands Instituut Voor Zuivelonderzoek (Nizo) Lantibiotics similar to nisin a, lactic acid bacteria which produce such lantibiotics, method for constructing such lactic acid bacteria and method for preserving foodstuffs with the aid of these lantibiotics and these lactic acid bacteria producing lantibiotics
GB9207267D0 (en) * 1992-04-02 1992-05-13 Agricultural & Food Res Nisins

Also Published As

Publication number Publication date
DE69534133T2 (de) 2006-03-02
JPH11500604A (ja) 1999-01-19
CA2205204A1 (en) 1996-05-30
EP0793727A1 (en) 1997-09-10
US6448034B1 (en) 2002-09-10
NZ295425A (en) 1999-07-29
CZ152197A3 (en) 1997-10-15
FI972100A0 (fi) 1997-05-16
NO972277D0 (no) 1997-05-20
DE69534133D1 (de) 2005-05-12
WO1996016180A1 (en) 1996-05-30
KR970707290A (ko) 1997-12-01
BR9510454A (pt) 1998-12-15
AU708788B2 (en) 1999-08-12
GB9423404D0 (en) 1995-01-11
HUT77421A (hu) 1998-04-28
CN1085249C (zh) 2002-05-22
ATE292686T1 (de) 2005-04-15
CN1171134A (zh) 1998-01-21
NO972277L (no) 1997-05-20
EP0793727B1 (en) 2005-04-06
PL320328A1 (en) 1997-09-29
FI972100A (fi) 1997-07-16
AU3876195A (en) 1996-06-17

Similar Documents

Publication Publication Date Title
Nardi et al. Cloning and DNA sequence analysis of an X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. lactis NCDO 763
Buist et al. Autolysis of Lactococcus lactis caused by induced overproduction of its major autolysin, AcmA
EP0579730B1 (en) Lantibiotics similar to nisin a, lactic acid bacteria which produce such lantibiotics, method for constructing such lactic acid bacteria and method for preserving foodstuffs with the aid of these lantibiotics and these lactic acid bacteria producing lantibiotics
US5691185A (en) Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria
US5580787A (en) Cloning vector for use in lactic acid bacteria
SK62297A3 (en) Production of variant nisin
JP3553065B2 (ja) 挿入プロモーター含有の組換え乳酸菌とその構築方法
US7655775B2 (en) Expression vectors for treating bacterial infections
US5939317A (en) Use of a Sec-dependent secretion system for secreting proteins that are usually secreted by a Sec-independent secretion system, bacteria containing it and their use
US20080233086A1 (en) Expression Vectors for Treating Bacterial Infections
van der Vossen et al. Characterization of transcription initiation and termination signals of the proteinase genes of Lactococcus lactis Wg2 and enhancement of proteolysis in L. lactis
US6100056A (en) Nisins
WO2006063425A1 (en) Expression vectors for treating bacterial infections
US7358083B1 (en) Food-grade cloning vector and their use in lactic acid bacteria
CA2325664C (en) Food-grade cloning vector and their use in lactic acid bacteria
VAN DER VOSSEN et al. Wg2 and Enhancement of Proteolysis in L. lactis
David Genetics of mesophilic citrate metabolizing lactic acid bacteria
NZ229125A (en) Cloning vectors of the pfx family including a sequence from plasmid pdi 25 of l. lactis 5136
AU2012200936A1 (en) Improved bacterial host cell for the direct expression of peptides