SK57696A3 - Polypeptide with xyloglucan endo-transglycosylase activity, method of its manufacture, nucleotide strand, dna vector - Google Patents
Polypeptide with xyloglucan endo-transglycosylase activity, method of its manufacture, nucleotide strand, dna vector Download PDFInfo
- Publication number
- SK57696A3 SK57696A3 SK576-96A SK57696A SK57696A3 SK 57696 A3 SK57696 A3 SK 57696A3 SK 57696 A SK57696 A SK 57696A SK 57696 A3 SK57696 A3 SK 57696A3
- Authority
- SK
- Slovakia
- Prior art keywords
- sequence
- amino acid
- polypeptide
- seq
- ser
- Prior art date
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- 108010069678 xyloglucan endotransglycosylase Proteins 0.000 title claims abstract description 72
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 51
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 41
- 230000000694 effects Effects 0.000 title claims abstract description 40
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 38
- 239000002773 nucleotide Substances 0.000 title claims description 47
- 125000003729 nucleotide group Chemical group 0.000 title claims description 47
- 238000000034 method Methods 0.000 title claims description 23
- 239000013598 vector Substances 0.000 title claims description 13
- 238000004519 manufacturing process Methods 0.000 title description 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract description 35
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract description 13
- 150000001413 amino acids Chemical class 0.000 claims description 32
- 108090000623 proteins and genes Proteins 0.000 claims description 31
- 210000004027 cell Anatomy 0.000 claims description 28
- 229920002000 Xyloglucan Polymers 0.000 claims description 27
- 108020004414 DNA Proteins 0.000 claims description 15
- 230000014509 gene expression Effects 0.000 claims description 10
- 230000012010 growth Effects 0.000 claims description 9
- 230000035800 maturation Effects 0.000 claims description 9
- 238000002955 isolation Methods 0.000 claims description 4
- 239000001963 growth medium Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 244000005700 microbiome Species 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 description 46
- 240000003768 Solanum lycopersicum Species 0.000 description 40
- 241000196324 Embryophyta Species 0.000 description 39
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 34
- 239000002299 complementary DNA Substances 0.000 description 34
- 229940024606 amino acid Drugs 0.000 description 28
- 235000001014 amino acid Nutrition 0.000 description 28
- 108020004707 nucleic acids Proteins 0.000 description 27
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- 150000007523 nucleic acids Chemical class 0.000 description 27
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- 206010061592 cardiac fibrillation Diseases 0.000 description 25
- 230000002600 fibrillogenic effect Effects 0.000 description 25
- 239000012634 fragment Substances 0.000 description 18
- 108090000790 Enzymes Proteins 0.000 description 14
- 102000004190 Enzymes Human genes 0.000 description 14
- 235000007849 Lepidium sativum Nutrition 0.000 description 14
- 244000211187 Lepidium sativum Species 0.000 description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 14
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 239000000872 buffer Substances 0.000 description 12
- 210000002421 cell wall Anatomy 0.000 description 12
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 241000588724 Escherichia coli Species 0.000 description 8
- 108010076504 Protein Sorting Signals Proteins 0.000 description 8
- 235000013399 edible fruits Nutrition 0.000 description 8
- 108010050848 glycylleucine Proteins 0.000 description 8
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- 210000003754 fetus Anatomy 0.000 description 7
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- 238000004458 analytical method Methods 0.000 description 6
- 229920001542 oligosaccharide Polymers 0.000 description 6
- 150000002482 oligosaccharides Chemical class 0.000 description 6
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 5
- GIKFNMZSGYAPEJ-HJGDQZAQSA-N Lys-Thr-Asp Chemical compound [H]N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O GIKFNMZSGYAPEJ-HJGDQZAQSA-N 0.000 description 5
- NSTPXGARCQOSAU-VIFPVBQESA-N N-formyl-L-phenylalanine Chemical compound O=CN[C@H](C(=O)O)CC1=CC=CC=C1 NSTPXGARCQOSAU-VIFPVBQESA-N 0.000 description 5
- 229920002684 Sepharose Polymers 0.000 description 5
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 5
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 5
- 235000011130 ammonium sulphate Nutrition 0.000 description 5
- 239000001913 cellulose Substances 0.000 description 5
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- FSXRLASFHBWESK-UHFFFAOYSA-N dipeptide phenylalanyl-tyrosine Natural products C=1C=C(O)C=CC=1CC(C(O)=O)NC(=O)C(N)CC1=CC=CC=C1 FSXRLASFHBWESK-UHFFFAOYSA-N 0.000 description 5
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- FFEUXEAKYRCACT-PEDHHIEDSA-N Arg-Ile-Ile Chemical compound CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(N)=N)[C@@H](C)CC)C(O)=O FFEUXEAKYRCACT-PEDHHIEDSA-N 0.000 description 4
- PDUHNKAFQXQNLH-ZETCQYMHSA-N Gly-Lys-Gly Chemical compound NCCCC[C@H](NC(=O)CN)C(=O)NCC(O)=O PDUHNKAFQXQNLH-ZETCQYMHSA-N 0.000 description 4
- JBCLFWXMTIKCCB-UHFFFAOYSA-N H-Gly-Phe-OH Natural products NCC(=O)NC(C(O)=O)CC1=CC=CC=C1 JBCLFWXMTIKCCB-UHFFFAOYSA-N 0.000 description 4
- XLXPYSDGMXTTNQ-UHFFFAOYSA-N Ile-Phe-Leu Natural products CCC(C)C(N)C(=O)NC(C(=O)NC(CC(C)C)C(O)=O)CC1=CC=CC=C1 XLXPYSDGMXTTNQ-UHFFFAOYSA-N 0.000 description 4
- XOWMDXHFSBCAKQ-SRVKXCTJSA-N Leu-Ser-Leu Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H](C(O)=O)CC(C)C XOWMDXHFSBCAKQ-SRVKXCTJSA-N 0.000 description 4
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 description 4
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- 108091034117 Oligonucleotide Proteins 0.000 description 4
- FSXRLASFHBWESK-HOTGVXAUSA-N Phe-Tyr Chemical compound C([C@H](N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)C1=CC=CC=C1 FSXRLASFHBWESK-HOTGVXAUSA-N 0.000 description 4
- BIBYEFRASCNLAA-CDMKHQONSA-N Thr-Phe-Gly Chemical compound C[C@@H](O)[C@H](N)C(=O)N[C@H](C(=O)NCC(O)=O)CC1=CC=CC=C1 BIBYEFRASCNLAA-CDMKHQONSA-N 0.000 description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 4
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- 108010083879 xyloglucan endo(1-4)-beta-D-glucanase Proteins 0.000 description 4
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- JQDFGZKKXBEANU-IMJSIDKUSA-N Ala-Cys Chemical compound C[C@H](N)C(=O)N[C@@H](CS)C(O)=O JQDFGZKKXBEANU-IMJSIDKUSA-N 0.000 description 3
- NLOMBWNGESDVJU-GUBZILKMSA-N Ala-Met-Arg Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O NLOMBWNGESDVJU-GUBZILKMSA-N 0.000 description 3
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- BGZCJDGBBUUBHA-KKUMJFAQSA-N Leu-Lys-Leu Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O BGZCJDGBBUUBHA-KKUMJFAQSA-N 0.000 description 3
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- AGYXCMYVTBYGCT-ULQDDVLXSA-N Phe-Arg-Leu Chemical compound [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O AGYXCMYVTBYGCT-ULQDDVLXSA-N 0.000 description 3
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- SMFGCTXUBWEPKM-KBPBESRZSA-N Phe-Leu-Gly Chemical compound OC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC1=CC=CC=C1 SMFGCTXUBWEPKM-KBPBESRZSA-N 0.000 description 3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01207—Xyloglucan:xyloglucosyl transferase (2.4.1.207)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939323225A GB9323225D0 (en) | 1993-11-10 | 1993-11-10 | Novel plant enzyme |
| PCT/GB1994/002467 WO1995013384A1 (en) | 1993-11-10 | 1994-11-10 | Tomato xyloglucan endo-transglycosylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK57696A3 true SK57696A3 (en) | 1996-10-02 |
Family
ID=10744976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK576-96A SK57696A3 (en) | 1993-11-10 | 1994-11-10 | Polypeptide with xyloglucan endo-transglycosylase activity, method of its manufacture, nucleotide strand, dna vector |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6215044B1 (pt) |
| EP (1) | EP0728208B1 (pt) |
| JP (1) | JPH09511121A (pt) |
| AT (1) | ATE236256T1 (pt) |
| AU (1) | AU698844B2 (pt) |
| CA (1) | CA2176133A1 (pt) |
| CZ (1) | CZ136196A3 (pt) |
| DE (1) | DE69432427T2 (pt) |
| DK (1) | DK0728208T3 (pt) |
| ES (1) | ES2196048T3 (pt) |
| GB (1) | GB9323225D0 (pt) |
| HU (1) | HUT74598A (pt) |
| PL (1) | PL317046A1 (pt) |
| PT (1) | PT728208E (pt) |
| SK (1) | SK57696A3 (pt) |
| WO (1) | WO1995013384A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0868559B1 (en) * | 1995-12-21 | 2003-05-14 | Novozymes A/S | Use of xyloglucan endotransglycosylase (xet) |
| AU6205198A (en) * | 1997-02-26 | 1998-09-18 | Novo Nordisk A/S | Microbial xyloglucan endotransglycosylase (xet) |
| AU736192B2 (en) * | 1997-07-27 | 2001-07-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Transgenic plants of altered morphology and the isolated arabidopsis thaliana endo-1,4-beta-glucanase gene, promoter and protein |
| GB9720038D0 (en) * | 1997-09-19 | 1997-11-19 | Nickerson Biocem Ltd | Control |
| EP1082017B1 (en) * | 1998-05-29 | 2005-03-09 | Novozymes A/S | Method for using xyloglucan endotransglycosylase in baking, pasta and steambread production, and doughs and baking additives comprising xyloglucan endotransglycosylase |
| GB0307294D0 (en) * | 2003-03-29 | 2003-05-07 | Univ Southampton | A novel genetic approach to improve the processability of fresh produce |
| ATE527371T1 (de) * | 2005-03-24 | 2011-10-15 | Biogenerix Ag | Expression löslicher, aktiver, eukaryotischer glucosyltransferasen in prokaryotischen organismen |
| MX2016011413A (es) | 2014-03-05 | 2017-02-28 | Novozymes As | Formulaciones que comprenden xiloglucano polimérico como portador para agentes agronómicamente beneficiosos. |
| WO2015134729A1 (en) | 2014-03-05 | 2015-09-11 | Novozymes A/S | Compositions and methods for improving properties of non-cellulosic textile materials with xyloglucan endotransglycosylase |
| WO2015134737A1 (en) | 2014-03-05 | 2015-09-11 | Novozymes A/S | Compositions and methods for improving properties of cellulosic textile materials with xyloglucan endotransglycosylase |
| WO2015134773A1 (en) | 2014-03-05 | 2015-09-11 | Novozymes A/S | Compositions and methods for functionalizing and linking materials |
| US10123535B2 (en) | 2014-03-05 | 2018-11-13 | Novozymes A/S | Compositions and methods for improving post-harvest properties of agricultural crops |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA931333B (en) * | 1992-02-28 | 1994-08-25 | Unilever Plc | Recombinant plant enzyme. |
| JP2898499B2 (ja) | 1992-03-26 | 1999-06-02 | 寳酒造株式会社 | エンド型キシログルカン転移酵素遺伝子 |
-
1993
- 1993-11-10 GB GB939323225A patent/GB9323225D0/en active Pending
-
1994
- 1994-11-10 CA CA002176133A patent/CA2176133A1/en not_active Abandoned
- 1994-11-10 AT AT95900233T patent/ATE236256T1/de not_active IP Right Cessation
- 1994-11-10 PL PL94317046A patent/PL317046A1/xx unknown
- 1994-11-10 JP JP7513686A patent/JPH09511121A/ja active Pending
- 1994-11-10 DE DE69432427T patent/DE69432427T2/de not_active Expired - Fee Related
- 1994-11-10 AU AU81129/94A patent/AU698844B2/en not_active Ceased
- 1994-11-10 WO PCT/GB1994/002467 patent/WO1995013384A1/en active IP Right Grant
- 1994-11-10 HU HU9601232A patent/HUT74598A/hu unknown
- 1994-11-10 EP EP95900233A patent/EP0728208B1/en not_active Expired - Lifetime
- 1994-11-10 ES ES95900233T patent/ES2196048T3/es not_active Expired - Lifetime
- 1994-11-10 US US08/640,737 patent/US6215044B1/en not_active Expired - Fee Related
- 1994-11-10 PT PT95900233T patent/PT728208E/pt unknown
- 1994-11-10 CZ CZ961361A patent/CZ136196A3/cs unknown
- 1994-11-10 SK SK576-96A patent/SK57696A3/sk unknown
- 1994-11-10 DK DK95900233T patent/DK0728208T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| HUT74598A (en) | 1997-01-28 |
| PL317046A1 (en) | 1997-03-03 |
| GB9323225D0 (en) | 1994-01-05 |
| JPH09511121A (ja) | 1997-11-11 |
| PT728208E (pt) | 2003-08-29 |
| AU8112994A (en) | 1995-05-29 |
| ES2196048T3 (es) | 2003-12-16 |
| ATE236256T1 (de) | 2003-04-15 |
| CA2176133A1 (en) | 1995-05-18 |
| DK0728208T3 (da) | 2003-07-21 |
| US6215044B1 (en) | 2001-04-10 |
| DE69432427D1 (de) | 2003-05-08 |
| AU698844B2 (en) | 1998-11-12 |
| EP0728208B1 (en) | 2003-04-02 |
| DE69432427T2 (de) | 2004-03-18 |
| CZ136196A3 (en) | 1996-12-11 |
| HU9601232D0 (en) | 1996-06-28 |
| WO1995013384A1 (en) | 1995-05-18 |
| EP0728208A1 (en) | 1996-08-28 |
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