SK284825B6 - Miniatúrny ventil na plnenie napájacieho zásobníka aparátu na transdermálnu aplikáciu lieku - Google Patents
Miniatúrny ventil na plnenie napájacieho zásobníka aparátu na transdermálnu aplikáciu lieku Download PDFInfo
- Publication number
- SK284825B6 SK284825B6 SK639-99A SK63999A SK284825B6 SK 284825 B6 SK284825 B6 SK 284825B6 SK 63999 A SK63999 A SK 63999A SK 284825 B6 SK284825 B6 SK 284825B6
- Authority
- SK
- Slovakia
- Prior art keywords
- layer
- charge
- miniature valve
- substrate
- silicon
- Prior art date
Links
- 238000011049 filling Methods 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 title claims abstract description 14
- 239000000758 substrate Substances 0.000 claims abstract description 55
- 238000002485 combustion reaction Methods 0.000 claims abstract description 18
- 239000010410 layer Substances 0.000 claims description 102
- 239000000463 material Substances 0.000 claims description 47
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 25
- 229910052581 Si3N4 Inorganic materials 0.000 claims description 24
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 claims description 24
- 229910052814 silicon oxide Inorganic materials 0.000 claims description 21
- 239000007789 gas Substances 0.000 claims description 19
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 18
- 239000012530 fluid Substances 0.000 claims description 18
- 238000004519 manufacturing process Methods 0.000 claims description 18
- 229910052710 silicon Inorganic materials 0.000 claims description 18
- 239000010703 silicon Substances 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 17
- 230000002238 attenuated effect Effects 0.000 claims description 16
- 229920001220 nitrocellulos Polymers 0.000 claims description 15
- 239000000020 Nitrocellulose Substances 0.000 claims description 14
- 229910004298 SiO 2 Inorganic materials 0.000 claims description 12
- 238000005530 etching Methods 0.000 claims description 11
- 239000013543 active substance Substances 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 10
- 229910052751 metal Inorganic materials 0.000 claims description 10
- 230000006378 damage Effects 0.000 claims description 9
- 230000001681 protective effect Effects 0.000 claims description 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 8
- 239000004065 semiconductor Substances 0.000 claims description 7
- 230000008021 deposition Effects 0.000 claims description 5
- 229910021420 polycrystalline silicon Inorganic materials 0.000 claims description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 4
- 229910021529 ammonia Inorganic materials 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims description 2
- MROCJMGDEKINLD-UHFFFAOYSA-N dichlorosilane Chemical compound Cl[SiH2]Cl MROCJMGDEKINLD-UHFFFAOYSA-N 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- 229910052990 silicon hydride Inorganic materials 0.000 claims description 2
- 238000010292 electrical insulation Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 239000011241 protective layer Substances 0.000 claims 1
- 238000001947 vapour-phase growth Methods 0.000 claims 1
- 238000001962 electrophoresis Methods 0.000 abstract description 2
- 239000000446 fuel Substances 0.000 abstract 2
- 239000002737 fuel gas Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 21
- 230000036571 hydration Effects 0.000 description 10
- 238000006703 hydration reaction Methods 0.000 description 10
- 229940079593 drug Drugs 0.000 description 7
- 238000013271 transdermal drug delivery Methods 0.000 description 6
- 238000000151 deposition Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 239000000017 hydrogel Substances 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 230000003213 activating effect Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 230000000670 limiting effect Effects 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 230000003387 muscular Effects 0.000 description 3
- 238000001020 plasma etching Methods 0.000 description 3
- 238000004080 punching Methods 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 238000012377 drug delivery Methods 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 238000005265 energy consumption Methods 0.000 description 2
- 229920002457 flexible plastic Polymers 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 125000003055 glycidyl group Chemical group C(C1CO1)* 0.000 description 2
- 238000009776 industrial production Methods 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- NCGICGYLBXGBGN-UHFFFAOYSA-N 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride Chemical compound Cl.[N-]1OC(=N)C=[N+]1N1CCOCC1 NCGICGYLBXGBGN-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000567 combustion gas Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000002716 delivery method Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940088679 drug related substance Drugs 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002493 microarray Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000004767 nitrides Chemical class 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- LCCNCVORNKJIRZ-UHFFFAOYSA-N parathion Chemical compound CCOP(=S)(OCC)OC1=CC=C([N+]([O-])=O)C=C1 LCCNCVORNKJIRZ-UHFFFAOYSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 238000003969 polarography Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- BJAARRARQJZURR-UHFFFAOYSA-N trimethylazanium;hydroxide Chemical compound O.CN(C)C BJAARRARQJZURR-UHFFFAOYSA-N 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
- F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
- F15C5/00—Manufacture of fluid circuit elements; Manufacture of assemblages of such elements integrated circuits
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/003—Valves for single use only
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0065—Operating means specially adapted for microvalves using chemical activation
- F16K99/0067—Operating means specially adapted for microvalves using chemical activation actuated by a pyrotechnical charge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0073—Fabrication methods specifically adapted for microvalves
- F16K2099/0074—Fabrication methods specifically adapted for microvalves using photolithography, e.g. etching
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0073—Fabrication methods specifically adapted for microvalves
- F16K2099/008—Multi-layer fabrications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0086—Medical applications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/1624—Destructible or deformable element controlled
- Y10T137/1632—Destructible element
- Y10T137/1647—Explosive actuation
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Dispersion Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Fluid Mechanics (AREA)
- Theoretical Computer Science (AREA)
- Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Medical Informatics (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Closures For Containers (AREA)
- Portable Nailing Machines And Staplers (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9614230A FR2756032B1 (fr) | 1996-11-21 | 1996-11-21 | Vanne miniature et son procede de fabrication, dispositif de remplissage de reservoir comprenant une telle vanne |
FR9706613A FR2764034B3 (fr) | 1997-05-29 | 1997-05-29 | Vanne miniature et son procede de fabrication |
PCT/FR1997/002101 WO1998022719A1 (fr) | 1996-11-21 | 1997-11-20 | Vanne miniature pour le remplissage du reservoir d'un appareil d'administration transdermique de medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
SK63999A3 SK63999A3 (en) | 2000-05-16 |
SK284825B6 true SK284825B6 (sk) | 2005-12-01 |
Family
ID=26233113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK639-99A SK284825B6 (sk) | 1996-11-21 | 1997-11-20 | Miniatúrny ventil na plnenie napájacieho zásobníka aparátu na transdermálnu aplikáciu lieku |
Country Status (18)
Country | Link |
---|---|
US (1) | US6247485B1 (es) |
EP (1) | EP0939862B1 (es) |
JP (1) | JP4114087B2 (es) |
KR (1) | KR100453439B1 (es) |
AT (1) | ATE213309T1 (es) |
AU (1) | AU725913B2 (es) |
BR (1) | BR9713381A (es) |
CA (1) | CA2272326C (es) |
CZ (1) | CZ294564B6 (es) |
DE (2) | DE69710486T2 (es) |
ES (1) | ES2138575T3 (es) |
HU (1) | HU222607B1 (es) |
IL (1) | IL130043A0 (es) |
NO (1) | NO322934B1 (es) |
NZ (1) | NZ336015A (es) |
PL (1) | PL185319B1 (es) |
SK (1) | SK284825B6 (es) |
WO (1) | WO1998022719A1 (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
US6131385A (en) * | 1997-08-18 | 2000-10-17 | Trw Inc. | Integrated pulsed propulsion system for microsatellite |
FR2774684B1 (fr) * | 1998-02-10 | 2000-03-03 | Poudres & Explosifs Ste Nale | Nouveaux materiaux pyrotechniques non detonables pour microsystemes |
EP1987854A1 (en) | 1998-07-14 | 2008-11-05 | Altea Therapeutics Corporation | Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport |
US6349740B1 (en) * | 1999-04-08 | 2002-02-26 | Abbott Laboratories | Monolithic high performance miniature flow control unit |
US20030078499A1 (en) * | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
WO2001012157A1 (en) * | 1999-08-18 | 2001-02-22 | Microchips, Inc. | Thermally-activated microchip chemical delivery devices |
US6378292B1 (en) | 2000-11-10 | 2002-04-30 | Honeywell International Inc. | MEMS microthruster array |
FR2828245B1 (fr) * | 2001-04-27 | 2005-11-11 | Poudres & Explosifs Ste Nale | Microactionneurs pyrotechniques pour microsystemes |
FR2827377B1 (fr) * | 2001-07-13 | 2003-12-05 | Poudres & Explosifs Ste Nale | Dispositif d'allumage pour microcharges pyrotechniques |
US7392080B2 (en) * | 2002-03-11 | 2008-06-24 | Altea Therapeutics Corporation | Transdermal drug delivery patch system, method of making same and method of using same |
FR2836907B1 (fr) * | 2002-03-11 | 2005-03-18 | Commissariat Energie Atomique | Microvanne a actionnement pyrotechnique |
US8116860B2 (en) * | 2002-03-11 | 2012-02-14 | Altea Therapeutics Corporation | Transdermal porator and patch system and method for using same |
US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
US6953455B2 (en) * | 2002-07-30 | 2005-10-11 | Hospira, Inc. | Medicine delivery system |
FR2846318B1 (fr) * | 2002-10-24 | 2005-01-07 | Commissariat Energie Atomique | Microstructure electromecanique integree comportant des moyens de reglage de la pression dans une cavite scellee et procede de reglage de la pression |
US6800070B2 (en) * | 2002-11-07 | 2004-10-05 | George Mazidji | Lockable tranquilizer bracelet |
FR2847246B1 (fr) * | 2002-11-19 | 2005-07-08 | Poudres & Explosifs Ste Nale | Microactionneur pyrotechnique double effet pour microsysteme et microsysteme utilisant un tel microactionneur |
FR2856046B1 (fr) | 2003-06-16 | 2005-07-29 | Biomerieux Sa | Microvanne fluidique a ouverture par commande electrique |
FR2857427B1 (fr) | 2003-07-10 | 2005-08-26 | Biomerieux Sa | Vanne a commande electrique comprenant une membrane microporeuse |
US7470266B2 (en) * | 2003-09-16 | 2008-12-30 | I-Flow Corporation | Fluid medication delivery device |
US8016811B2 (en) * | 2003-10-24 | 2011-09-13 | Altea Therapeutics Corporation | Method for transdermal delivery of permeant substances |
FR2865508B1 (fr) | 2004-01-27 | 2006-03-03 | Snpe Materiaux Energetiques | Microsysteme pyrotechnique et procede de fabrication d'un microsysteme. |
US7780981B2 (en) | 2004-09-13 | 2010-08-24 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
US7827983B2 (en) * | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
FR2883860B1 (fr) * | 2005-03-29 | 2007-06-08 | Commissariat Energie Atomique | Procede de fabrication de micro-canaux enterres et micro-dispositif comprenant de tels micro-canaux. |
US20070075079A1 (en) * | 2005-10-05 | 2007-04-05 | Harlan Stokes | Flavored container lid |
DE102010051743B4 (de) | 2010-11-19 | 2022-09-01 | C. Miethke Gmbh & Co. Kg | Programmierbares Hydrocephalusventil |
CN103523738B (zh) * | 2012-07-06 | 2016-07-06 | 无锡华润上华半导体有限公司 | 微机电系统薄片及其制备方法 |
CA2974324A1 (en) | 2015-01-28 | 2016-08-04 | Zita S. Netzel | Drug delivery methods and systems |
ES1157758Y (es) * | 2016-04-27 | 2016-08-22 | Descansare Sleep Lab S L | Dispositivo de control de flujo de aire |
US20180100601A1 (en) * | 2016-10-08 | 2018-04-12 | Zepto Life Technology, LLC | Electrolytic membrane valve |
US20180135770A1 (en) * | 2016-11-11 | 2018-05-17 | Honeywell International Inc. | Apparatus and methods for thermally activated micro-valve |
WO2018106723A1 (en) * | 2016-12-05 | 2018-06-14 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
CA3049529A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
KR102075594B1 (ko) * | 2017-11-13 | 2020-02-11 | 재단법인대구경북과학기술원 | 약물 전달 장치 및 이의 제조방법 |
US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3184097A (en) | 1962-01-19 | 1965-05-18 | Earl E Kilmer | Valve with exploding diaphragm |
US4622031A (en) * | 1983-08-18 | 1986-11-11 | Drug Delivery Systems Inc. | Indicator for electrophoretic transcutaneous drug delivery device |
US5135479A (en) * | 1983-08-18 | 1992-08-04 | Drug Delivery Systems, Inc. | Programmable control and mounting system for transdermal drug applicator |
US5186001A (en) * | 1991-11-08 | 1993-02-16 | University Of Southern California | Transient energy release microdevices and methods |
US5310404A (en) * | 1992-06-01 | 1994-05-10 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
US5366454A (en) * | 1993-03-17 | 1994-11-22 | La Corporation De L'ecole Polytechnique | Implantable medication dispensing device |
-
1997
- 1997-11-20 JP JP52329398A patent/JP4114087B2/ja not_active Expired - Lifetime
- 1997-11-20 WO PCT/FR1997/002101 patent/WO1998022719A1/fr active IP Right Grant
- 1997-11-20 BR BR9713381A patent/BR9713381A/pt not_active IP Right Cessation
- 1997-11-20 HU HU0001065A patent/HU222607B1/hu active IP Right Grant
- 1997-11-20 IL IL13004397A patent/IL130043A0/xx not_active IP Right Cessation
- 1997-11-20 SK SK639-99A patent/SK284825B6/sk not_active IP Right Cessation
- 1997-11-20 NZ NZ33601597A patent/NZ336015A/xx not_active IP Right Cessation
- 1997-11-20 DE DE1997610486 patent/DE69710486T2/de not_active Expired - Lifetime
- 1997-11-20 CA CA 2272326 patent/CA2272326C/en not_active Expired - Lifetime
- 1997-11-20 PL PL97333628A patent/PL185319B1/pl unknown
- 1997-11-20 ES ES97947111T patent/ES2138575T3/es not_active Expired - Lifetime
- 1997-11-20 KR KR10-1999-7004475A patent/KR100453439B1/ko not_active IP Right Cessation
- 1997-11-20 AT AT97947111T patent/ATE213309T1/de not_active IP Right Cessation
- 1997-11-20 US US09/285,000 patent/US6247485B1/en not_active Expired - Lifetime
- 1997-11-20 DE DE1997947111 patent/DE939862T1/de active Pending
- 1997-11-20 AU AU52277/98A patent/AU725913B2/en not_active Expired
- 1997-11-20 CZ CZ19991766A patent/CZ294564B6/cs not_active IP Right Cessation
- 1997-11-20 EP EP19970947111 patent/EP0939862B1/fr not_active Expired - Lifetime
-
1999
- 1999-05-21 NO NO19992481A patent/NO322934B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9713381A (pt) | 2000-03-21 |
EP0939862B1 (fr) | 2002-02-13 |
HUP0001065A3 (en) | 2001-02-28 |
EP0939862A1 (fr) | 1999-09-08 |
AU725913B2 (en) | 2000-10-26 |
ATE213309T1 (de) | 2002-02-15 |
DE939862T1 (de) | 2000-04-06 |
US6247485B1 (en) | 2001-06-19 |
NZ336015A (en) | 2000-11-24 |
HU222607B1 (hu) | 2003-08-28 |
DE69710486T2 (de) | 2002-10-31 |
HUP0001065A2 (hu) | 2000-08-28 |
ES2138575T3 (es) | 2002-10-01 |
CZ294564B6 (cs) | 2005-02-16 |
JP2001505491A (ja) | 2001-04-24 |
NO992481L (no) | 1999-05-21 |
JP4114087B2 (ja) | 2008-07-09 |
SK63999A3 (en) | 2000-05-16 |
AU5227798A (en) | 1998-06-10 |
PL185319B1 (pl) | 2003-04-30 |
DE69710486D1 (de) | 2002-03-21 |
KR100453439B1 (ko) | 2004-10-15 |
CA2272326A1 (en) | 1998-05-28 |
KR20000069060A (ko) | 2000-11-25 |
CA2272326C (en) | 2005-03-29 |
ES2138575T1 (es) | 2000-01-16 |
CZ176699A3 (cs) | 2000-02-16 |
NO322934B1 (no) | 2006-12-18 |
IL130043A0 (en) | 2000-02-29 |
WO1998022719A1 (fr) | 1998-05-28 |
NO992481D0 (no) | 1999-05-21 |
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Legal Events
Date | Code | Title | Description |
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MK4A | Patent expired |
Expiry date: 20171120 |