SK283441B6 - Deriváty 5-aryl-3-(8-azabicyklo[3.2.1]okt-3-yl)-1,3,4- oxadiazol-2(3H)-ónu ako ligandy receptora 5-HT4, spôsob ich prípravy a farmaceutický prostriedok s ich obsahom - Google Patents

Deriváty 5-aryl-3-(8-azabicyklo[3.2.1]okt-3-yl)-1,3,4- oxadiazol-2(3H)-ónu ako ligandy receptora 5-HT4, spôsob ich prípravy a farmaceutický prostriedok s ich obsahom Download PDF

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Publication number
SK283441B6
SK283441B6 SK1426-99A SK142699A SK283441B6 SK 283441 B6 SK283441 B6 SK 283441B6 SK 142699 A SK142699 A SK 142699A SK 283441 B6 SK283441 B6 SK 283441B6
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SK
Slovakia
Prior art keywords
azabicyclo
oxadiazol
oct
formula
group
Prior art date
Application number
SK1426-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK142699A3 (en
Inventor
Samir Jegham
Alistair Lochead
Fr�D�Ric Galli
Alain Nedelec
Axelle Samson
Thierry Gallet
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of SK142699A3 publication Critical patent/SK142699A3/sk
Publication of SK283441B6 publication Critical patent/SK283441B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1426-99A 1997-04-18 1998-04-15 Deriváty 5-aryl-3-(8-azabicyklo[3.2.1]okt-3-yl)-1,3,4- oxadiazol-2(3H)-ónu ako ligandy receptora 5-HT4, spôsob ich prípravy a farmaceutický prostriedok s ich obsahom SK283441B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9704802A FR2762316B1 (fr) 1997-04-18 1997-04-18 Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
PCT/FR1998/000754 WO1998047898A1 (fr) 1997-04-18 1998-04-15 Derives de 5-aryl-3-(8-azabicyclo(3.2.2)oct-3-yl)-1,3,4-oxadiazol-2(3h)-one en tant que ligands des recepteurs 5-ht4

Publications (2)

Publication Number Publication Date
SK142699A3 SK142699A3 (en) 2000-05-16
SK283441B6 true SK283441B6 (sk) 2003-07-01

Family

ID=9506076

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1426-99A SK283441B6 (sk) 1997-04-18 1998-04-15 Deriváty 5-aryl-3-(8-azabicyklo[3.2.1]okt-3-yl)-1,3,4- oxadiazol-2(3H)-ónu ako ligandy receptora 5-HT4, spôsob ich prípravy a farmaceutický prostriedok s ich obsahom

Country Status (32)

Country Link
US (1) US6255319B1 (bg)
EP (1) EP0975631B1 (bg)
JP (1) JP2001521542A (bg)
KR (1) KR20010006452A (bg)
CN (1) CN1260794A (bg)
AR (1) AR012458A1 (bg)
AT (1) ATE206424T1 (bg)
AU (1) AU742666B2 (bg)
BG (1) BG64053B1 (bg)
BR (1) BR9808926A (bg)
CA (1) CA2286106A1 (bg)
CO (1) CO4750656A1 (bg)
CZ (1) CZ289154B6 (bg)
DE (1) DE69801905T2 (bg)
DK (1) DK0975631T3 (bg)
EE (1) EE03769B1 (bg)
ES (1) ES2165162T3 (bg)
FR (1) FR2762316B1 (bg)
HU (1) HUP0002456A3 (bg)
IL (1) IL132352A0 (bg)
NO (1) NO995040L (bg)
NZ (1) NZ500396A (bg)
PL (1) PL186894B1 (bg)
PT (1) PT975631E (bg)
RU (1) RU2186066C2 (bg)
SI (1) SI0975631T1 (bg)
SK (1) SK283441B6 (bg)
TR (1) TR199902600T2 (bg)
TW (1) TW502005B (bg)
UA (1) UA57071C2 (bg)
WO (1) WO1998047898A1 (bg)
ZA (1) ZA983257B (bg)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0211230D0 (en) * 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
AU2004226452B2 (en) * 2003-03-26 2008-07-24 Merck Sharp & Dohme Corp. Bicyclic piperidine derivatives as melanocortin-4 receptor agonists
JP2007511559A (ja) * 2003-11-18 2007-05-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 固形医薬製剤
WO2005123718A2 (en) 2004-06-15 2005-12-29 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
SE532388C2 (sv) * 2008-03-14 2010-01-12 Tetra Laval Holdings & Finance Förpackningslaminat och -behållare med två separata gasbarriärskikt samt metod för deras framställning
JP6348568B2 (ja) * 2013-03-15 2018-06-27 モンサント テクノロジー エルエルシー 線虫害虫防除のためのｎ−，ｃ−二置換アゾール
GB201814151D0 (en) * 2018-08-31 2018-10-17 Ucl Business Plc Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2135414T3 (es) * 1991-09-12 1999-11-01 Smithkline Beecham Plc Antagonistas del receptor 5-ht4.
DE69319939T2 (de) * 1992-02-04 1999-02-18 Eisai Co., Ltd., Tokio/Tokyo Aminobenzoesäure Derivate
AU667874B2 (en) * 1992-02-06 1996-04-18 Smithkline Beecham Plc Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
SK282335B6 (sk) * 1995-11-09 2002-01-07 Sanofi-Synthelabo Deriváty 5-fenyl-3-(piperidin-4-yl)-1,3,4,-oxadiazol-2(3H)-ónu, spôsob ich prípravy a farmaceutický prostriedok, ktorý ich obsahuje

Also Published As

Publication number Publication date
SI0975631T1 (en) 2002-06-30
DE69801905D1 (de) 2001-11-08
EP0975631B1 (fr) 2001-10-04
PT975631E (pt) 2002-03-28
DK0975631T3 (da) 2002-01-28
AU742666B2 (en) 2002-01-10
CN1260794A (zh) 2000-07-19
JP2001521542A (ja) 2001-11-06
DE69801905T2 (de) 2002-07-04
FR2762316A1 (fr) 1998-10-23
BG103810A (bg) 2000-06-30
ES2165162T3 (es) 2002-03-01
CZ289154B6 (cs) 2001-11-14
CZ364199A3 (cs) 2000-03-15
NO995040D0 (no) 1999-10-15
KR20010006452A (ko) 2001-01-26
UA57071C2 (uk) 2003-06-16
ZA983257B (en) 1998-10-19
BR9808926A (pt) 2000-08-01
EP0975631A1 (fr) 2000-02-02
AR012458A1 (es) 2000-10-18
ATE206424T1 (de) 2001-10-15
AU7341598A (en) 1998-11-13
PL186894B1 (pl) 2004-03-31
EE03769B1 (et) 2002-06-17
WO1998047898A1 (fr) 1998-10-29
FR2762316B1 (fr) 1999-12-17
BG64053B1 (bg) 2003-11-28
HUP0002456A2 (hu) 2000-12-28
IL132352A0 (en) 2001-03-19
RU2186066C2 (ru) 2002-07-27
EE9900487A (et) 2000-06-15
NZ500396A (en) 2001-04-27
TR199902600T2 (xx) 2000-03-21
HUP0002456A3 (en) 2001-03-28
PL336315A1 (en) 2000-06-19
SK142699A3 (en) 2000-05-16
TW502005B (en) 2002-09-11
US6255319B1 (en) 2001-07-03
NO995040L (no) 1999-12-16
CO4750656A1 (es) 1999-03-31
CA2286106A1 (en) 1998-10-29

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