SK2382002A3 - Drug for treating fractures - Google Patents

Drug for treating fractures Download PDF

Info

Publication number
SK2382002A3
SK2382002A3 SK238-2002A SK2382002A SK2382002A3 SK 2382002 A3 SK2382002 A3 SK 2382002A3 SK 2382002 A SK2382002 A SK 2382002A SK 2382002 A3 SK2382002 A3 SK 2382002A3
Authority
SK
Slovakia
Prior art keywords
bone
medicament
bisphosphonate
group
administered
Prior art date
Application number
SK238-2002A
Other languages
English (en)
Slovak (sk)
Inventor
David G Little
Original Assignee
Royal Alexandra Hosp Children
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Royal Alexandra Hosp Children filed Critical Royal Alexandra Hosp Children
Publication of SK2382002A3 publication Critical patent/SK2382002A3/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK238-2002A 1999-08-19 2000-08-17 Drug for treating fractures SK2382002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPQ2325A AUPQ232599A0 (en) 1999-08-19 1999-08-19 Drug for treating fractures
PCT/AU2000/000982 WO2001013922A1 (en) 1999-08-19 2000-08-17 Drug for treating fractures

Publications (1)

Publication Number Publication Date
SK2382002A3 true SK2382002A3 (en) 2002-09-10

Family

ID=3816500

Family Applications (1)

Application Number Title Priority Date Filing Date
SK238-2002A SK2382002A3 (en) 1999-08-19 2000-08-17 Drug for treating fractures

Country Status (16)

Country Link
EP (1) EP1214079A4 (hu)
JP (1) JP2003507426A (hu)
KR (1) KR20020027562A (hu)
CN (1) CN100345548C (hu)
AU (1) AUPQ232599A0 (hu)
BR (1) BR0013416A (hu)
CA (1) CA2381302A1 (hu)
HK (1) HK1048441B (hu)
HU (1) HUP0202396A3 (hu)
IL (1) IL148166A0 (hu)
NO (1) NO20020784D0 (hu)
NZ (1) NZ517538A (hu)
PL (1) PL353485A1 (hu)
SK (1) SK2382002A3 (hu)
WO (1) WO2001013922A1 (hu)
ZA (1) ZA200202160B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1365769T3 (da) 2001-02-06 2011-05-16 Sydney Children S Hospitals Network Randwick And Westmead Incorporating The Royal Alexandra Hospital Lægemiddel til behandling af osteonekrose og til behandling af patienter med risiko for at udvikle osteonekrose
US20040157798A1 (en) * 2001-04-03 2004-08-12 Little David Graham Drug for use in bone grafting
AUPR553701A0 (en) * 2001-06-07 2001-07-12 Royal Alexandra Hospital For Children, The A device for the delivery of a drug to a fractured bone
ES2561463T3 (es) * 2003-08-21 2016-02-26 Addbio Ab Dispositivo de implante recubierto con bisfosfonato y método para el mismo
AU2004273672A1 (en) * 2003-09-19 2005-03-31 Wisconsin Alumni Research Foundation Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin D derivatives and a bisphosphonate
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
ITMI20040641A1 (it) * 2004-03-31 2004-06-30 Tb Technology S R L Composizioni bioadesive bifunzionali per implantologia orale
AR048742A1 (es) * 2004-12-22 2006-05-24 Gador Sa Sistema de aplicacion de medicamentos intra-oral
ATE537807T1 (de) 2005-10-27 2012-01-15 Thommen Medical Ag Dentalimplantat und verfahren zu dessen herstellung
US8882740B2 (en) 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8107560A (pt) * 1981-11-19 1983-07-05 Luiz Romariz Duarte Estimulacao ultra-sonica da consolidacao de fraturas osseas
SK74594A3 (en) * 1991-12-17 1995-01-12 Procter & Gamble Pharma Treatment for treating of osteoporosis
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
AU670337B2 (en) * 1992-11-30 1996-07-11 Novartis Ag Use of certain methanebisphosphonic acid derivatives in fracture healing
JPH08505142A (ja) * 1992-12-23 1996-06-04 メルク エンド カンパニー インコーポレーテッド 骨損失を治療及び予防するためのビスホスホネート/エストロゲン療法
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
GB9408775D0 (en) * 1994-05-04 1994-06-22 Ciba Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
US5616571A (en) * 1995-06-06 1997-04-01 Merck & Co., Inc. Bisphosphonates prevent bone loss associated with immunosuppressive therapy
AU703887B2 (en) * 1995-06-06 1999-04-01 Merck & Co., Inc. Bisphosphonate therapy for bone loss associated with rheumatoid arthritis
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
GB9613722D0 (en) * 1996-06-28 1996-08-28 Univ Liverpool Chemical compounds

Also Published As

Publication number Publication date
CA2381302A1 (en) 2001-03-01
PL353485A1 (en) 2003-11-17
KR20020027562A (ko) 2002-04-13
BR0013416A (pt) 2002-04-30
AUPQ232599A0 (en) 1999-09-09
HK1048441B (zh) 2008-02-22
NO20020784L (no) 2002-02-18
JP2003507426A (ja) 2003-02-25
EP1214079A4 (en) 2004-03-24
CN100345548C (zh) 2007-10-31
HK1048441A1 (en) 2003-04-04
NO20020784D0 (no) 2002-02-18
ZA200202160B (en) 2003-08-27
NZ517538A (en) 2003-07-25
CN1370071A (zh) 2002-09-18
HUP0202396A3 (en) 2005-02-28
WO2001013922A1 (en) 2001-03-01
EP1214079A1 (en) 2002-06-19
HUP0202396A2 (hu) 2002-11-28
IL148166A0 (en) 2002-09-12

Similar Documents

Publication Publication Date Title
WO2002098307A1 (en) A device for the delivery of a drug to a fractured bone
US20040157798A1 (en) Drug for use in bone grafting
JPH09512268A (ja) 整形外科的人工器官移植後の骨吸収を阻害するためのビスホスホネートの使用
Tudor et al. Static and dynamic periosteal elevation: a pilot study in a pig model
US10046082B2 (en) Collagen sponge containing a drug for promoting fracture healing and method for preparing the same
JPH08510996A (ja) 骨の手術へのビスホスホネートの使用
AU2002244520A1 (en) A drug for use in bone grafting
NO310057B1 (no) Anvendelse av visse metanbisfosfonsyrederivater for å forhindre lösning av protese og protesemigrering
Pampu et al. Experimental evaluation of the effects of zoledronic acid on regenerate bone formation and osteoporosis in mandibular distraction osteogenesis
WO1996039107A1 (en) Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
SK2382002A3 (en) Drug for treating fractures
Tarvainen et al. Effect of clodronate on fracture healing in denervated rats
JP2024037985A (ja) 人工骨膜
Harding et al. A single dose zoledronic acid enhances pin fixation in high tibial osteotomy using the hemicallotasis technique. A double-blind placebo controlled randomized study in 46 patients
US20220023493A1 (en) Compositions and methods for regeneration of bone tissue
ES2247842T3 (es) Uso de ibandronato para promover la oseo-integracion de endoprotesis.
AU781068B2 (en) Drug for treating fractures
Schortinghuis et al. Does ultrasound stimulate osteoconduction? A placebo-controlled single-blind study using collagen membranes in the rat mandible
Saghieh et al. The impact of zoledronic acid on regenerate and native bone after consolidation and removal of the external fixator: an animal model study
RU2816809C1 (ru) Способ прагматизации репаративного остеогенеза трубчатых костей животных
RU2250789C2 (ru) Способ лечения повреждений костей при замедленной консолидации
Adachi et al. Inhibition of osteoclast recruitment at a local site by 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP)
RU2469679C1 (ru) Способ сочетанной стимуляции репаративного остеогенеза у животных
Heidari et al. Effect of risedronate on bone resorption during the consolidation phase of distraction osteogenesis: a rabbit model
Green et al. Postoperative Care, Day by Day

Legal Events

Date Code Title Description
FC9A Refused patent application