SK19222001A3 - Polykatiónové biokonjugáty na transport aktívnych látok - Google Patents
Polykatiónové biokonjugáty na transport aktívnych látok Download PDFInfo
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- SK19222001A3 SK19222001A3 SK1922-2001A SK19222001A SK19222001A3 SK 19222001 A3 SK19222001 A3 SK 19222001A3 SK 19222001 A SK19222001 A SK 19222001A SK 19222001 A3 SK19222001 A3 SK 19222001A3
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- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000026792 palmitoylation Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 229960003330 pentetic acid Drugs 0.000 description 1
- 239000000813 peptide hormone Substances 0.000 description 1
- 150000003904 phospholipids Chemical group 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 125000003367 polycyclic group Chemical group 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 108010055896 polyornithine Proteins 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 239000011814 protection agent Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 230000010837 receptor-mediated endocytosis Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000009097 single-agent therapy Methods 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 229940014800 succinic anhydride Drugs 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyamides (AREA)
- Polyesters Or Polycarbonates (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902217A HUP9902217A3 (en) | 1999-06-29 | 1999-06-29 | Polycation based bioconjugates and process for producing thereof |
| PCT/HU2000/000061 WO2001000242A2 (en) | 1999-06-29 | 2000-06-28 | Polycation-based bioconjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK19222001A3 true SK19222001A3 (sk) | 2004-05-04 |
Family
ID=89998595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1922-2001A SK19222001A3 (sk) | 1999-06-29 | 2000-06-28 | Polykatiónové biokonjugáty na transport aktívnych látok |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6727347B1 (de) |
| EP (1) | EP1202748B1 (de) |
| JP (1) | JP2003503363A (de) |
| KR (1) | KR100795093B1 (de) |
| CN (1) | CN1371288A (de) |
| AT (1) | ATE408420T1 (de) |
| AU (1) | AU784031B2 (de) |
| BR (1) | BR0012633A (de) |
| CA (1) | CA2377074A1 (de) |
| CZ (1) | CZ20014701A3 (de) |
| DE (1) | DE60040294D1 (de) |
| EE (1) | EE200100715A (de) |
| HU (1) | HUP9902217A3 (de) |
| IL (2) | IL147380A0 (de) |
| MX (1) | MXPA02000450A (de) |
| NO (1) | NO20016391L (de) |
| NZ (1) | NZ516666A (de) |
| PL (1) | PL353933A1 (de) |
| RU (1) | RU2250782C2 (de) |
| SK (1) | SK19222001A3 (de) |
| UA (1) | UA76940C2 (de) |
| WO (1) | WO2001000242A2 (de) |
| ZA (1) | ZA200200266B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP9902217A3 (en) * | 1999-06-29 | 2002-07-29 | Szegoe Peter | Polycation based bioconjugates and process for producing thereof |
| AU2001281499B2 (en) * | 2000-03-21 | 2007-01-04 | Wisconsin Alumni Research Foundation | Methods and reagents for regulation of cellular responses in biological systems |
| US7923560B2 (en) | 2003-04-10 | 2011-04-12 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| US8168922B2 (en) * | 2004-10-18 | 2012-05-01 | Lincoln Global, Inc. | Self-shielded flux cored electrode |
| US7834065B2 (en) * | 2005-01-31 | 2010-11-16 | Bmg Incorporated | Medical-use two part reactive adhesive and medical-use resin having self-degradation property |
| JP4989039B2 (ja) * | 2005-04-27 | 2012-08-01 | Ｊｎｃ株式会社 | 核酸複合体及びそれを用いる細胞内への核酸導入方法 |
| WO2009157209A1 (ja) | 2008-06-27 | 2009-12-30 | 株式会社バイオベルデ | 細胞および組織の凍結保存用組成物 |
| CN101891889B (zh) * | 2010-08-18 | 2012-05-23 | 中国科学院长春应用化学研究所 | 阳离子聚合物及其制备方法 |
| US8541556B1 (en) | 2012-03-02 | 2013-09-24 | Empire Technology Development Llc | Lignin derivatives and uses thereof |
| WO2014003753A1 (en) * | 2012-06-28 | 2014-01-03 | Empire Technology Development Llc | Lignin derivatives having polycations and uses thereof |
| EP2944195A1 (de) * | 2014-05-15 | 2015-11-18 | Monier Tadros | Negativ geladene Matrix und Verwendung davon |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847240A (en) | 1978-01-16 | 1989-07-11 | The Trustees Of Boston University | Method of effecting cellular uptake of molecules |
| US4701521A (en) | 1978-07-17 | 1987-10-20 | The Trustees Of Boston University | Method of effecting cellular uptake of molecules |
| JPS6356501A (ja) * | 1986-08-26 | 1988-03-11 | Chisso Corp | アフイニテイークロマトグラフイー用カラム充填剤及びその製造方法 |
| HU202553B (en) | 1987-10-21 | 1991-03-28 | Mta Kutatas Es Szervezetelemzo | Process for producing isopolypeptides composed of diamino monokarboxylic acids and pharmaceutical compositions comprising same, as well as plant protective comprising polyisolysine |
| JPH0413741A (ja) * | 1990-05-02 | 1992-01-17 | Chisso Corp | ペクチン・ポリリシン高分子電解質複合体 |
| JPH05246963A (ja) * | 1992-03-02 | 1993-09-24 | Kanegafuchi Chem Ind Co Ltd | ε−ポリリジン誘導体 |
| DE4331011A1 (de) * | 1993-09-13 | 1995-03-16 | Bayer Ag | Nukleinsäuren-bindende Oligomere mit C-Verzweigung für Therapie und Diagnostik |
| JP4606524B2 (ja) * | 1997-11-19 | 2011-01-05 | チッソ株式会社 | ポリリジン、及びポリリジンの製造方法、及びポリリジン組成物、及びエンドトキシンを除去する医薬品の生産方法 |
| HUP9902217A3 (en) * | 1999-06-29 | 2002-07-29 | Szegoe Peter | Polycation based bioconjugates and process for producing thereof |
-
1999
- 1999-06-29 HU HU9902217A patent/HUP9902217A3/hu active IP Right Revival
-
2000
- 2000-06-28 PL PL00353933A patent/PL353933A1/xx unknown
- 2000-06-28 MX MXPA02000450A patent/MXPA02000450A/es active IP Right Grant
- 2000-06-28 SK SK1922-2001A patent/SK19222001A3/sk unknown
- 2000-06-28 AU AU58351/00A patent/AU784031B2/en not_active Ceased
- 2000-06-28 UA UA2002010706A patent/UA76940C2/uk unknown
- 2000-06-28 WO PCT/HU2000/000061 patent/WO2001000242A2/en active Search and Examination
- 2000-06-28 DE DE60040294T patent/DE60040294D1/de not_active Expired - Fee Related
- 2000-06-28 JP JP2001505949A patent/JP2003503363A/ja active Pending
- 2000-06-28 CA CA002377074A patent/CA2377074A1/en not_active Abandoned
- 2000-06-28 CZ CZ20014701A patent/CZ20014701A3/cs unknown
- 2000-06-28 EE EEP200100715A patent/EE200100715A/xx unknown
- 2000-06-28 CN CN00812216A patent/CN1371288A/zh active Pending
- 2000-06-28 EP EP00944116A patent/EP1202748B1/de not_active Expired - Lifetime
- 2000-06-28 NZ NZ516666A patent/NZ516666A/en unknown
- 2000-06-28 KR KR1020017016890A patent/KR100795093B1/ko not_active IP Right Cessation
- 2000-06-28 AT AT00944116T patent/ATE408420T1/de not_active IP Right Cessation
- 2000-06-28 BR BR0012633-0A patent/BR0012633A/pt not_active IP Right Cessation
- 2000-06-28 US US10/018,806 patent/US6727347B1/en not_active Expired - Fee Related
- 2000-06-28 RU RU2002102071/15A patent/RU2250782C2/ru not_active IP Right Cessation
- 2000-06-28 IL IL14738000A patent/IL147380A0/xx active IP Right Grant
-
2001
- 2001-12-27 IL IL147380A patent/IL147380A/en not_active IP Right Cessation
- 2001-12-27 NO NO20016391A patent/NO20016391L/no not_active Application Discontinuation
-
2002
- 2002-01-11 ZA ZA200200266A patent/ZA200200266B/xx unknown
-
2004
- 2004-02-23 US US10/782,962 patent/US7090846B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR0012633A (pt) | 2002-04-02 |
| US7090846B2 (en) | 2006-08-15 |
| IL147380A (en) | 2007-02-11 |
| CA2377074A1 (en) | 2001-01-04 |
| MXPA02000450A (es) | 2002-07-02 |
| WO2001000242A3 (en) | 2001-11-22 |
| AU784031B2 (en) | 2006-01-19 |
| AU5835100A (en) | 2001-01-31 |
| KR100795093B1 (ko) | 2008-01-17 |
| HUP9902217A2 (hu) | 2001-04-28 |
| RU2250782C2 (ru) | 2005-04-27 |
| HU9902217D0 (en) | 1999-08-30 |
| NZ516666A (en) | 2004-04-30 |
| EP1202748A2 (de) | 2002-05-08 |
| ATE408420T1 (de) | 2008-10-15 |
| JP2003503363A (ja) | 2003-01-28 |
| US20040220083A1 (en) | 2004-11-04 |
| KR20020031352A (ko) | 2002-05-01 |
| WO2001000242A2 (en) | 2001-01-04 |
| NO20016391D0 (no) | 2001-12-27 |
| IL147380A0 (en) | 2002-08-14 |
| ZA200200266B (en) | 2003-06-25 |
| DE60040294D1 (de) | 2008-10-30 |
| EP1202748B1 (de) | 2008-09-17 |
| NO20016391L (no) | 2002-02-04 |
| US6727347B1 (en) | 2004-04-27 |
| CN1371288A (zh) | 2002-09-25 |
| PL353933A1 (en) | 2003-12-15 |
| UA76940C2 (en) | 2006-10-16 |
| CZ20014701A3 (cs) | 2002-06-12 |
| EE200100715A (et) | 2003-02-17 |
| HUP9902217A3 (en) | 2002-07-29 |
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