SK18793A3 - Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application - Google Patents

Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application Download PDF

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Publication number
SK18793A3
SK18793A3 SK18793A SK18793A SK18793A3 SK 18793 A3 SK18793 A3 SK 18793A3 SK 18793 A SK18793 A SK 18793A SK 18793 A SK18793 A SK 18793A SK 18793 A3 SK18793 A3 SK 18793A3
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
straight
branched alkyl
branched
Prior art date
Application number
SK18793A
Other languages
English (en)
Slovak (sk)
Inventor
Ulrich Mueller
Mathias Mueller-Gliemann
Juergen Dressel
Peter Fey
Rudolf Hanko
Walter Huebsch
Thomas Kraemer
Martin Beuck
Stanislav Kazda
Stefan Wohlfeil
Oezkan Yalkinoglu
Andreas Knorr
Johannes-Peter Stasch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SK18793A3 publication Critical patent/SK18793A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK18793A 1992-03-13 1993-03-11 Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application SK18793A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4208051A DE4208051A1 (de) 1992-03-13 1992-03-13 Substituierte phenylessigsaeureamide

Publications (1)

Publication Number Publication Date
SK18793A3 true SK18793A3 (en) 1993-10-06

Family

ID=6453994

Family Applications (1)

Application Number Title Priority Date Filing Date
SK18793A SK18793A3 (en) 1992-03-13 1993-03-11 Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application

Country Status (18)

Country Link
US (1) US5352687A (ko)
EP (1) EP0560163A1 (ko)
JP (1) JPH0616646A (ko)
KR (1) KR930019633A (ko)
CN (1) CN1076443A (ko)
AU (1) AU654427B2 (ko)
CA (1) CA2091434A1 (ko)
CZ (1) CZ29793A3 (ko)
DE (1) DE4208051A1 (ko)
FI (1) FI931089A (ko)
HU (1) HUT64040A (ko)
IL (1) IL104999A0 (ko)
MX (1) MX9301125A (ko)
NO (1) NO930760L (ko)
NZ (1) NZ247127A (ko)
SK (1) SK18793A3 (ko)
TW (1) TW223632B (ko)
ZA (1) ZA931773B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
DE4212796A1 (de) * 1992-04-16 1993-10-21 Bayer Ag Propenoyl-imidazolderivate
DE4302957A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Imidazolyl-substituierte Phenylessigsäureprolinamide
DE19525028A1 (de) * 1995-07-10 1997-01-16 Bayer Ag Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen
DE19535504A1 (de) * 1995-09-25 1997-03-27 Bayer Ag Substituierte Xanthine
DE19536378A1 (de) * 1995-09-29 1997-04-03 Bayer Ag Heterocyclische Aryl-, Alkyl- und Cycloalkylessigsäureamide
DE19546919A1 (de) * 1995-12-15 1997-06-19 Bayer Ag N-Heterocyclisch substituierte Phenylessigsäure-Derivate
DE19546918A1 (de) * 1995-12-15 1997-06-19 Bayer Ag Bicyclische Heterocyclen
US6774236B1 (en) 1996-04-04 2004-08-10 Bayer Aktiengesellschaft Process for the preparation of enantiomerically pure cycloalkano-indol -and azaindol -and pyrimido [1,2A]indolcarbocyclic acids and their activated derivatives
DE19613550A1 (de) * 1996-04-04 1997-10-09 Bayer Ag Neue Pyrimido[1,2-a]indole
DE19613549A1 (de) * 1996-04-04 1997-10-09 Bayer Ag Verfahren zur Herstellung von enantiomerenreinen Cycloalkano-indol- und azaindol-carbonsäuren und deren aktivierte Derivate
DE19619950A1 (de) 1996-04-17 1997-10-23 Bayer Ag Heterocyclisch-substituierte Phenylglycinolamide
EP0802192A1 (de) * 1996-04-17 1997-10-22 Bayer Ag Heterocyclisch-substituierte Phenylglycinolamide mit antiatherosklerotischer Wirkung und Verfahren zu ihrer Herstellung
US6465502B1 (en) 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
DE60021521T4 (de) * 1999-09-29 2006-09-21 Ortho-Mcneil Pharmaceutical, Inc. Isonipecotamide zur behandlung von integrin vermittelten störungen
US6987131B1 (en) 2000-06-26 2006-01-17 Burzynski Stanislaw R Phenylacetic acid compositions for treating or preventing hypercholesterolemia
UA75093C2 (en) 2000-10-06 2006-03-15 Dimensional Pharm Inc Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5183810A (en) * 1990-02-13 1993-02-02 Merck & Co., Inc. Imidazole angiotensin II antagonists incorporating a substituted benzyl element
EP0515548A4 (en) * 1990-02-13 1993-03-10 Merck & Co. Inc. Imidazole angiotensin ii antagonists incorporating a substituted benzyl element
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate

Also Published As

Publication number Publication date
KR930019633A (ko) 1993-10-18
ZA931773B (en) 1993-09-29
AU3402693A (en) 1993-09-16
FI931089A0 (fi) 1993-03-11
NO930760D0 (no) 1993-03-02
US5352687A (en) 1994-10-04
IL104999A0 (en) 1993-07-08
HUT64040A (en) 1993-11-29
EP0560163A1 (de) 1993-09-15
NO930760L (no) 1993-09-14
FI931089A (fi) 1993-09-14
AU654427B2 (en) 1994-11-03
JPH0616646A (ja) 1994-01-25
CZ29793A3 (en) 1994-01-19
CN1076443A (zh) 1993-09-22
CA2091434A1 (en) 1993-09-14
MX9301125A (es) 1993-09-01
TW223632B (ko) 1994-05-11
HU9300721D0 (en) 1993-05-28
NZ247127A (en) 1994-09-27
DE4208051A1 (de) 1993-09-16

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