SK18793A3 - Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application - Google Patents
Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application Download PDFInfo
- Publication number
- SK18793A3 SK18793A3 SK18793A SK18793A SK18793A3 SK 18793 A3 SK18793 A3 SK 18793A3 SK 18793 A SK18793 A SK 18793A SK 18793 A SK18793 A SK 18793A SK 18793 A3 SK18793 A3 SK 18793A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- carbon atoms
- straight
- branched alkyl
- branched
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4208051A DE4208051A1 (de) | 1992-03-13 | 1992-03-13 | Substituierte phenylessigsaeureamide |
Publications (1)
Publication Number | Publication Date |
---|---|
SK18793A3 true SK18793A3 (en) | 1993-10-06 |
Family
ID=6453994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK18793A SK18793A3 (en) | 1992-03-13 | 1993-03-11 | Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application |
Country Status (18)
Country | Link |
---|---|
US (1) | US5352687A (fi) |
EP (1) | EP0560163A1 (fi) |
JP (1) | JPH0616646A (fi) |
KR (1) | KR930019633A (fi) |
CN (1) | CN1076443A (fi) |
AU (1) | AU654427B2 (fi) |
CA (1) | CA2091434A1 (fi) |
CZ (1) | CZ29793A3 (fi) |
DE (1) | DE4208051A1 (fi) |
FI (1) | FI931089A (fi) |
HU (1) | HUT64040A (fi) |
IL (1) | IL104999A0 (fi) |
MX (1) | MX9301125A (fi) |
NO (1) | NO930760L (fi) |
NZ (1) | NZ247127A (fi) |
SK (1) | SK18793A3 (fi) |
TW (1) | TW223632B (fi) |
ZA (1) | ZA931773B (fi) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5576342A (en) * | 1992-03-13 | 1996-11-19 | Bayer Aktiengesellschaft | Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives |
DE4309968A1 (de) * | 1993-03-26 | 1994-09-29 | Bayer Ag | Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten |
DE4212796A1 (de) * | 1992-04-16 | 1993-10-21 | Bayer Ag | Propenoyl-imidazolderivate |
DE4302957A1 (de) * | 1993-02-03 | 1994-08-04 | Bayer Ag | Imidazolyl-substituierte Phenylessigsäureprolinamide |
DE19525028A1 (de) * | 1995-07-10 | 1997-01-16 | Bayer Ag | Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen |
DE19535504A1 (de) * | 1995-09-25 | 1997-03-27 | Bayer Ag | Substituierte Xanthine |
DE19536378A1 (de) * | 1995-09-29 | 1997-04-03 | Bayer Ag | Heterocyclische Aryl-, Alkyl- und Cycloalkylessigsäureamide |
DE19546918A1 (de) * | 1995-12-15 | 1997-06-19 | Bayer Ag | Bicyclische Heterocyclen |
DE19546919A1 (de) * | 1995-12-15 | 1997-06-19 | Bayer Ag | N-Heterocyclisch substituierte Phenylessigsäure-Derivate |
US6774236B1 (en) | 1996-04-04 | 2004-08-10 | Bayer Aktiengesellschaft | Process for the preparation of enantiomerically pure cycloalkano-indol -and azaindol -and pyrimido [1,2A]indolcarbocyclic acids and their activated derivatives |
DE19613549A1 (de) * | 1996-04-04 | 1997-10-09 | Bayer Ag | Verfahren zur Herstellung von enantiomerenreinen Cycloalkano-indol- und azaindol-carbonsäuren und deren aktivierte Derivate |
DE19613550A1 (de) * | 1996-04-04 | 1997-10-09 | Bayer Ag | Neue Pyrimido[1,2-a]indole |
EP0802192A1 (de) * | 1996-04-17 | 1997-10-22 | Bayer Ag | Heterocyclisch-substituierte Phenylglycinolamide mit antiatherosklerotischer Wirkung und Verfahren zu ihrer Herstellung |
DE19619950A1 (de) | 1996-04-17 | 1997-10-23 | Bayer Ag | Heterocyclisch-substituierte Phenylglycinolamide |
US6465502B1 (en) | 1998-12-23 | 2002-10-15 | Novartis Ag | Additional therapeutic use |
RU2001114518A (ru) * | 1999-09-29 | 2003-04-20 | Орто-Макнейл Фармасьютикал, Инк. (Us) | Изонипекотамиды для лечения опосредованных интегринами нарушений |
US6987131B1 (en) | 2000-06-26 | 2006-01-17 | Burzynski Stanislaw R | Phenylacetic acid compositions for treating or preventing hypercholesterolemia |
UA75093C2 (en) | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
GB8911854D0 (en) * | 1989-05-23 | 1989-07-12 | Ici Plc | Heterocyclic compounds |
US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
US5183810A (en) * | 1990-02-13 | 1993-02-02 | Merck & Co., Inc. | Imidazole angiotensin II antagonists incorporating a substituted benzyl element |
JPH05504359A (ja) * | 1990-02-13 | 1993-07-08 | メルク・エンド・カムパニー・インコーポレーテツド | 置換ベンジル部分を含むイミダゾールアンギオテンシン2拮抗物質 |
DE4200954A1 (de) * | 1991-04-26 | 1992-10-29 | Bayer Ag | Heterocyclisch substituierte phenylessigsaeurederivate |
-
1992
- 1992-03-13 DE DE4208051A patent/DE4208051A1/de not_active Withdrawn
-
1993
- 1993-02-17 TW TW082101091A patent/TW223632B/zh active
- 1993-02-26 CZ CZ93297A patent/CZ29793A3/cs unknown
- 1993-03-01 EP EP93103219A patent/EP0560163A1/de not_active Withdrawn
- 1993-03-01 MX MX9301125A patent/MX9301125A/es unknown
- 1993-03-02 NO NO93930760A patent/NO930760L/no unknown
- 1993-03-03 US US08/025,479 patent/US5352687A/en not_active Expired - Lifetime
- 1993-03-05 AU AU34026/93A patent/AU654427B2/en not_active Ceased
- 1993-03-10 CA CA002091434A patent/CA2091434A1/en not_active Abandoned
- 1993-03-10 IL IL104999A patent/IL104999A0/xx unknown
- 1993-03-11 FI FI931089A patent/FI931089A/fi unknown
- 1993-03-11 NZ NZ247127A patent/NZ247127A/en unknown
- 1993-03-11 SK SK18793A patent/SK18793A3/sk unknown
- 1993-03-12 KR KR1019930003689A patent/KR930019633A/ko not_active Application Discontinuation
- 1993-03-12 HU HU9300721A patent/HUT64040A/hu unknown
- 1993-03-12 ZA ZA931773A patent/ZA931773B/xx unknown
- 1993-03-12 JP JP5077455A patent/JPH0616646A/ja active Pending
- 1993-03-13 CN CN93102258A patent/CN1076443A/zh not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2091434A1 (en) | 1993-09-14 |
IL104999A0 (en) | 1993-07-08 |
AU3402693A (en) | 1993-09-16 |
TW223632B (fi) | 1994-05-11 |
NO930760D0 (no) | 1993-03-02 |
US5352687A (en) | 1994-10-04 |
AU654427B2 (en) | 1994-11-03 |
MX9301125A (es) | 1993-09-01 |
CN1076443A (zh) | 1993-09-22 |
JPH0616646A (ja) | 1994-01-25 |
FI931089A (fi) | 1993-09-14 |
FI931089A0 (fi) | 1993-03-11 |
HU9300721D0 (en) | 1993-05-28 |
NZ247127A (en) | 1994-09-27 |
NO930760L (no) | 1993-09-14 |
CZ29793A3 (en) | 1994-01-19 |
ZA931773B (en) | 1993-09-29 |
HUT64040A (en) | 1993-11-29 |
KR930019633A (ko) | 1993-10-18 |
DE4208051A1 (de) | 1993-09-16 |
EP0560163A1 (de) | 1993-09-15 |
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