SK161199A3 - Cyanoguanidines as cell proliferation inhibitors - Google Patents
Cyanoguanidines as cell proliferation inhibitors Download PDFInfo
- Publication number
- SK161199A3 SK161199A3 SK1611-99A SK161199A SK161199A3 SK 161199 A3 SK161199 A3 SK 161199A3 SK 161199 A SK161199 A SK 161199A SK 161199 A3 SK161199 A3 SK 161199A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- cyano
- formula
- acid
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711119.9A GB9711119D0 (en) | 1997-05-29 | 1997-05-29 | Novel cyanoguanidines |
| PCT/DK1998/000195 WO1998054143A1 (en) | 1997-05-29 | 1998-05-15 | Cyanoguanidines as cell proliferation inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK161199A3 true SK161199A3 (en) | 2000-06-12 |
Family
ID=10813249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1611-99A SK161199A3 (en) | 1997-05-29 | 1998-05-15 | Cyanoguanidines as cell proliferation inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6121297A (is) |
| EP (1) | EP0984937A1 (is) |
| JP (1) | JP2001526693A (is) |
| KR (1) | KR20010013158A (is) |
| CN (1) | CN1314890A (is) |
| AU (1) | AU733093B2 (is) |
| BG (1) | BG103867A (is) |
| BR (1) | BR9809496A (is) |
| CA (1) | CA2291489A1 (is) |
| EA (1) | EA002037B1 (is) |
| EE (1) | EE03871B1 (is) |
| GB (1) | GB9711119D0 (is) |
| HK (1) | HK1039116A1 (is) |
| HU (1) | HUP0003150A3 (is) |
| IS (1) | IS5229A (is) |
| NZ (1) | NZ500702A (is) |
| PL (1) | PL337091A1 (is) |
| SK (1) | SK161199A3 (is) |
| WO (1) | WO1998054143A1 (is) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000061561A1 (en) | 1999-04-09 | 2000-10-19 | Shionogi Bioresearch Corp. | Cyanoguanidine compounds |
| AU1494702A (en) | 2000-11-21 | 2002-06-03 | Leo Pharma As | Cyanoguanidine prodrugs |
| US20030045515A1 (en) * | 2001-05-24 | 2003-03-06 | Lise Binderup | Combination medicament for treatment of neoplastic diseases |
| WO2002094265A1 (en) * | 2001-05-24 | 2002-11-28 | Leo Pharma A/S | A method of modulating nf-$g(k)b activity |
| US6642215B2 (en) * | 2001-05-24 | 2003-11-04 | Leo Pharma A/S | Method of modulating NF-kB activity |
| PL366459A1 (en) | 2001-05-24 | 2005-02-07 | Leo Pharma A/S | Novel pyridyl cyanoguanidine compounds |
| US7253193B2 (en) | 2002-05-17 | 2007-08-07 | Leo Pharma A/S | Cyanoguanidine prodrugs |
| WO2006066584A1 (en) | 2004-12-22 | 2006-06-29 | Leo Pharma A/S | Novel cyanoguanidine compounds |
| US8211912B2 (en) | 2007-09-26 | 2012-07-03 | Gemin X Pharmaceuticals Canada | Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl tranferase inhibitor |
| US8173677B2 (en) | 2007-09-26 | 2012-05-08 | Gemin X Pharmaceuticals Canada Inc. | Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| CA2751495C (en) | 2009-02-06 | 2013-08-20 | Tianjin Hemay Bio-Tech Co., Ltd. | Pharmaceutical compositions comprising a pyridyl cyanoguanidine and cyclodextrin and/or derivatives thereof |
| KR20140020823A (ko) | 2010-09-03 | 2014-02-19 | 포르마 티엠, 엘엘씨. | Ｎａｍｐｔ의 억제를 위한 구아니딘 화합물 및 조성물 |
| JP2013540781A (ja) | 2010-10-26 | 2013-11-07 | ティエンジン ホーメイ バイオ−テック カンパニー， リミテッド | Ｎ−（６−（４−クロロフェノキシ）ヘキシル）−ｎ’−シアノ−ｎ’’−（４−ピリジル）グアニジンの結晶多形とその製造及び使用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9219472D0 (en) * | 1992-09-15 | 1992-10-28 | Leo Pharm Prod Ltd | Chemical compounds |
-
1997
- 1997-05-29 GB GBGB9711119.9A patent/GB9711119D0/en active Pending
-
1998
- 1998-05-15 EA EA199901096A patent/EA002037B1/ru not_active IP Right Cessation
- 1998-05-15 US US09/424,655 patent/US6121297A/en not_active Expired - Fee Related
- 1998-05-15 BR BR9809496-3A patent/BR9809496A/pt not_active IP Right Cessation
- 1998-05-15 KR KR19997011141A patent/KR20010013158A/ko not_active Application Discontinuation
- 1998-05-15 AU AU76385/98A patent/AU733093B2/en not_active Ceased
- 1998-05-15 HU HU0003150A patent/HUP0003150A3/hu unknown
- 1998-05-15 JP JP50011399A patent/JP2001526693A/ja active Pending
- 1998-05-15 NZ NZ500702A patent/NZ500702A/en unknown
- 1998-05-15 CA CA002291489A patent/CA2291489A1/en not_active Abandoned
- 1998-05-15 WO PCT/DK1998/000195 patent/WO1998054143A1/en not_active Application Discontinuation
- 1998-05-15 CN CN98805480A patent/CN1314890A/zh active Pending
- 1998-05-15 SK SK1611-99A patent/SK161199A3/sk unknown
- 1998-05-15 EE EEP199900551A patent/EE03871B1/xx not_active IP Right Cessation
- 1998-05-15 EP EP98924054A patent/EP0984937A1/en not_active Withdrawn
- 1998-05-15 PL PL98337091A patent/PL337091A1/xx unknown
-
1999
- 1999-10-26 IS IS5229A patent/IS5229A/is unknown
- 1999-11-09 BG BG103867A patent/BG103867A/xx unknown
-
2002
- 2002-01-16 HK HK02100324.5A patent/HK1039116A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0003150A3 (en) | 2002-10-28 |
| IS5229A (is) | 1999-10-26 |
| JP2001526693A (ja) | 2001-12-18 |
| GB9711119D0 (en) | 1997-07-23 |
| AU7638598A (en) | 1998-12-30 |
| PL337091A1 (en) | 2000-07-31 |
| BR9809496A (pt) | 2000-06-20 |
| US6121297A (en) | 2000-09-19 |
| EE9900551A (et) | 2000-06-15 |
| HK1039116A1 (zh) | 2002-04-12 |
| EA199901096A1 (ru) | 2000-08-28 |
| BG103867A (en) | 2001-05-31 |
| HUP0003150A2 (en) | 2001-03-28 |
| EA002037B1 (ru) | 2001-12-24 |
| EE03871B1 (et) | 2002-10-15 |
| CN1314890A (zh) | 2001-09-26 |
| NZ500702A (en) | 2001-07-27 |
| CA2291489A1 (en) | 1998-12-03 |
| KR20010013158A (ko) | 2001-02-26 |
| AU733093B2 (en) | 2001-05-03 |
| WO1998054143A1 (en) | 1998-12-03 |
| EP0984937A1 (en) | 2000-03-15 |
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