SK161199A3 - Cyanoguanidines as cell proliferation inhibitors - Google Patents
Cyanoguanidines as cell proliferation inhibitors Download PDFInfo
- Publication number
- SK161199A3 SK161199A3 SK1611-99A SK161199A SK161199A3 SK 161199 A3 SK161199 A3 SK 161199A3 SK 161199 A SK161199 A SK 161199A SK 161199 A3 SK161199 A3 SK 161199A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- cyano
- formula
- acid
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711119.9A GB9711119D0 (en) | 1997-05-29 | 1997-05-29 | Novel cyanoguanidines |
| PCT/DK1998/000195 WO1998054143A1 (fr) | 1997-05-29 | 1998-05-15 | Nouvelles cyanoguanidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK161199A3 true SK161199A3 (en) | 2000-06-12 |
Family
ID=10813249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1611-99A SK161199A3 (en) | 1997-05-29 | 1998-05-15 | Cyanoguanidines as cell proliferation inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6121297A (fr) |
| EP (1) | EP0984937A1 (fr) |
| JP (1) | JP2001526693A (fr) |
| KR (1) | KR20010013158A (fr) |
| CN (1) | CN1314890A (fr) |
| AU (1) | AU733093B2 (fr) |
| BG (1) | BG103867A (fr) |
| BR (1) | BR9809496A (fr) |
| CA (1) | CA2291489A1 (fr) |
| EA (1) | EA002037B1 (fr) |
| EE (1) | EE03871B1 (fr) |
| GB (1) | GB9711119D0 (fr) |
| HK (1) | HK1039116A1 (fr) |
| HU (1) | HUP0003150A3 (fr) |
| IS (1) | IS5229A (fr) |
| NZ (1) | NZ500702A (fr) |
| PL (1) | PL337091A1 (fr) |
| SK (1) | SK161199A3 (fr) |
| WO (1) | WO1998054143A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000061561A1 (fr) | 1999-04-09 | 2000-10-19 | Shionogi Bioresearch Corp. | Composes a base de cyanoguanidine |
| AU1494702A (en) | 2000-11-21 | 2002-06-03 | Leo Pharma As | Cyanoguanidine prodrugs |
| WO2002094265A1 (fr) * | 2001-05-24 | 2002-11-28 | Leo Pharma A/S | Procede de modulation de l'activite de nf-kb |
| IL158574A0 (en) | 2001-05-24 | 2004-05-12 | Leo Pharma As | Novel pyridyl cyanoguanidine compounds |
| US20030045515A1 (en) * | 2001-05-24 | 2003-03-06 | Lise Binderup | Combination medicament for treatment of neoplastic diseases |
| US6642215B2 (en) | 2001-05-24 | 2003-11-04 | Leo Pharma A/S | Method of modulating NF-kB activity |
| US7253193B2 (en) | 2002-05-17 | 2007-08-07 | Leo Pharma A/S | Cyanoguanidine prodrugs |
| EP1838696B1 (fr) | 2004-12-22 | 2016-03-09 | Leo Pharma A/S | Composes de cyanoguanidine nouveaux |
| US8173677B2 (en) | 2007-09-26 | 2012-05-08 | Gemin X Pharmaceuticals Canada Inc. | Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| WO2009072004A2 (fr) | 2007-09-26 | 2009-06-11 | Gemin X Pharmaceuticals Canada, Inc. | Compositions et procédés pour influer sur les teneurs en nad+ en utilisant un inhibiteur de nicotinamide phosphoribosyle transférase |
| WO2010088842A1 (fr) | 2009-02-06 | 2010-08-12 | 天津和美生物技术有限公司 | Compositions pharmaceutiques contenant des pyridyl-cyanoguanidines, leurs méthodes de préparation et utilisations |
| US9676721B2 (en) | 2010-09-03 | 2017-06-13 | Forma Tm, Llc | Compounds and compositions for the inhibition of NAMPT |
| EP2634173A4 (fr) | 2010-10-26 | 2014-04-02 | Tianjin Hemay Bio Tech Co Ltd | Composé polymorphe de n-(6-(4-chlorophénoxy)hexyl)-n'-cyano-n''-(4-pyridyl)guanidine, et préparation de celui-ci et utilisation de celui-ci |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9219472D0 (en) * | 1992-09-15 | 1992-10-28 | Leo Pharm Prod Ltd | Chemical compounds |
-
1997
- 1997-05-29 GB GBGB9711119.9A patent/GB9711119D0/en active Pending
-
1998
- 1998-05-15 SK SK1611-99A patent/SK161199A3/sk unknown
- 1998-05-15 CA CA002291489A patent/CA2291489A1/fr not_active Abandoned
- 1998-05-15 EP EP98924054A patent/EP0984937A1/fr not_active Withdrawn
- 1998-05-15 EE EEP199900551A patent/EE03871B1/xx not_active IP Right Cessation
- 1998-05-15 AU AU76385/98A patent/AU733093B2/en not_active Ceased
- 1998-05-15 KR KR19997011141A patent/KR20010013158A/ko not_active Application Discontinuation
- 1998-05-15 NZ NZ500702A patent/NZ500702A/en unknown
- 1998-05-15 US US09/424,655 patent/US6121297A/en not_active Expired - Fee Related
- 1998-05-15 BR BR9809496-3A patent/BR9809496A/pt not_active IP Right Cessation
- 1998-05-15 JP JP50011399A patent/JP2001526693A/ja active Pending
- 1998-05-15 WO PCT/DK1998/000195 patent/WO1998054143A1/fr not_active Application Discontinuation
- 1998-05-15 HU HU0003150A patent/HUP0003150A3/hu unknown
- 1998-05-15 PL PL98337091A patent/PL337091A1/xx unknown
- 1998-05-15 EA EA199901096A patent/EA002037B1/ru not_active IP Right Cessation
- 1998-05-15 CN CN98805480A patent/CN1314890A/zh active Pending
-
1999
- 1999-10-26 IS IS5229A patent/IS5229A/is unknown
- 1999-11-09 BG BG103867A patent/BG103867A/xx unknown
-
2002
- 2002-01-16 HK HK02100324.5A patent/HK1039116A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL337091A1 (en) | 2000-07-31 |
| AU7638598A (en) | 1998-12-30 |
| BG103867A (en) | 2001-05-31 |
| EE03871B1 (et) | 2002-10-15 |
| EA002037B1 (ru) | 2001-12-24 |
| BR9809496A (pt) | 2000-06-20 |
| EA199901096A1 (ru) | 2000-08-28 |
| IS5229A (is) | 1999-10-26 |
| GB9711119D0 (en) | 1997-07-23 |
| HUP0003150A2 (en) | 2001-03-28 |
| AU733093B2 (en) | 2001-05-03 |
| EE9900551A (et) | 2000-06-15 |
| CA2291489A1 (fr) | 1998-12-03 |
| NZ500702A (en) | 2001-07-27 |
| US6121297A (en) | 2000-09-19 |
| KR20010013158A (ko) | 2001-02-26 |
| CN1314890A (zh) | 2001-09-26 |
| EP0984937A1 (fr) | 2000-03-15 |
| JP2001526693A (ja) | 2001-12-18 |
| WO1998054143A1 (fr) | 1998-12-03 |
| HK1039116A1 (zh) | 2002-04-12 |
| HUP0003150A3 (en) | 2002-10-28 |
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