SK120994A3 - 1,4-naphthoquinone derivatives with anti-protozoal and anti- -parasitic activity - Google Patents

1,4-naphthoquinone derivatives with anti-protozoal and anti- -parasitic activity Download PDF

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Publication number
SK120994A3
SK120994A3 SK1209-94A SK120994A SK120994A3 SK 120994 A3 SK120994 A3 SK 120994A3 SK 120994 A SK120994 A SK 120994A SK 120994 A3 SK120994 A3 SK 120994A3
Authority
SK
Slovakia
Prior art keywords
group
formula
compound
carbon atoms
alkyl
Prior art date
Application number
SK1209-94A
Other languages
English (en)
Slovak (sk)
Inventor
Alan T Hudson
Clive L Yeates
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SK120994A3 publication Critical patent/SK120994A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK1209-94A 1992-04-06 1993-04-05 1,4-naphthoquinone derivatives with anti-protozoal and anti- -parasitic activity SK120994A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929207517A GB9207517D0 (en) 1992-04-06 1992-04-06 Heterocyclic compounds
PCT/GB1993/000708 WO1993020044A1 (en) 1992-04-06 1993-04-05 1,4 naphthoquinone derivtives with anti-protozoal and anti-parasitic activity

Publications (1)

Publication Number Publication Date
SK120994A3 true SK120994A3 (en) 1995-07-11

Family

ID=10713546

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1209-94A SK120994A3 (en) 1992-04-06 1993-04-05 1,4-naphthoquinone derivatives with anti-protozoal and anti- -parasitic activity

Country Status (16)

Country Link
EP (1) EP0634996A1 (ko)
JP (1) JPH07505388A (ko)
KR (1) KR950700874A (ko)
CN (1) CN1083048A (ko)
AU (1) AU3899293A (ko)
CA (1) CA2133744A1 (ko)
CZ (1) CZ242994A3 (ko)
FI (1) FI944657A (ko)
GB (1) GB9207517D0 (ko)
HU (1) HUT68937A (ko)
IL (1) IL105322A0 (ko)
MX (1) MX9301962A (ko)
NO (1) NO943737L (ko)
SK (1) SK120994A3 (ko)
WO (1) WO1993020044A1 (ko)
ZA (1) ZA932458B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013093937A2 (en) * 2011-09-16 2013-06-27 Alkem Laboratories Ltd. ''3-(5-methyl-2-oxo-l, 3-dioxol-4-yl) methyloxy-2- trans-[(4-chloro phenyl) cyclohexyl] [1,4]naphthaquinone"-atovaquone prodrug
BR112018076619A2 (pt) 2016-06-20 2019-04-02 The Scripps Research Institute composições antimalariais e usos das mesmas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485116A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
GB8310141D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
SG23618G (en) * 1988-08-16 1995-09-18 Wellcome Found Naphthoquinones for the treatment and prophylaxis of pneumocystis carinii infections

Also Published As

Publication number Publication date
WO1993020044A1 (en) 1993-10-14
MX9301962A (es) 1993-11-01
NO943737D0 (no) 1994-10-05
CZ242994A3 (en) 1995-06-14
AU3899293A (en) 1993-11-08
HU9402850D0 (en) 1995-01-30
FI944657A0 (fi) 1994-10-05
KR950700874A (ko) 1995-02-20
CA2133744A1 (en) 1993-10-14
JPH07505388A (ja) 1995-06-15
GB9207517D0 (en) 1992-05-20
CN1083048A (zh) 1994-03-02
IL105322A0 (en) 1993-08-18
NO943737L (no) 1994-11-29
HUT68937A (en) 1995-08-28
ZA932458B (en) 1994-10-05
EP0634996A1 (en) 1995-01-25
FI944657A (fi) 1994-12-02

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