SI3220946T1 - Sestave in metode za lajšanje in preprečevanje vnetja črevesja zaradi prisotnosti antigenov peptidnih živil v črevesu - Google Patents

Sestave in metode za lajšanje in preprečevanje vnetja črevesja zaradi prisotnosti antigenov peptidnih živil v črevesu

Info

Publication number
SI3220946T1
SI3220946T1 SI201531696T SI201531696T SI3220946T1 SI 3220946 T1 SI3220946 T1 SI 3220946T1 SI 201531696 T SI201531696 T SI 201531696T SI 201531696 T SI201531696 T SI 201531696T SI 3220946 T1 SI3220946 T1 SI 3220946T1
Authority
SI
Slovenia
Prior art keywords
intestine
relieving
compositions
methods
intestinal inflammation
Prior art date
Application number
SI201531696T
Other languages
English (en)
Slovenian (sl)
Inventor
David Schriemer
Martial Rey
Original Assignee
Codexis, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis, Inc. filed Critical Codexis, Inc.
Publication of SI3220946T1 publication Critical patent/SI3220946T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23Aspartic endopeptidases (3.4.23)
    • C12Y304/23012Nepenthesin (3.4.23.12)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
SI201531696T 2014-06-16 2015-06-16 Sestave in metode za lajšanje in preprečevanje vnetja črevesja zaradi prisotnosti antigenov peptidnih živil v črevesu SI3220946T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462012865P 2014-06-16 2014-06-16
US201562118396P 2015-02-19 2015-02-19
PCT/CA2015/000389 WO2015192211A1 (en) 2014-06-16 2015-06-16 Compositions and methods for treating gluten intolerance and disorders arising therefrom
EP15809878.0A EP3220946B1 (en) 2014-06-16 2015-06-16 Compositions and methods for attenuating and preventing intestinal inflammation due to the presence of peptidic food antigens in an intestine

Publications (1)

Publication Number Publication Date
SI3220946T1 true SI3220946T1 (sl) 2021-11-30

Family

ID=54934596

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201531696T SI3220946T1 (sl) 2014-06-16 2015-06-16 Sestave in metode za lajšanje in preprečevanje vnetja črevesja zaradi prisotnosti antigenov peptidnih živil v črevesu

Country Status (8)

Country Link
US (3) US20160022785A1 (enExample)
EP (2) EP3943104A1 (enExample)
JP (2) JP6829077B2 (enExample)
CN (2) CN113827708A (enExample)
DK (1) DK3220946T3 (enExample)
ES (1) ES2883347T3 (enExample)
SI (1) SI3220946T1 (enExample)
WO (1) WO2015192211A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160022785A1 (en) 2014-06-16 2016-01-28 Nepetx, Llc Compositions and methods for treating gluten intolerance and disorders arising therefrom
JP2019504011A (ja) 2015-12-16 2019-02-14 ネプエトゥクス,エルエルシー グルテン不耐症およびそれにより発生する障害を治療するための組成物および方法
CN108504615B (zh) * 2018-03-30 2020-12-29 江南大学 一种产酸性蛋白酶的重组菌及其应用
EP4522200A2 (en) * 2022-05-10 2025-03-19 Codexis, Inc. Recombinant neprosin polypeptides and methods of expression
CN115336666A (zh) * 2022-07-05 2022-11-15 熊子奕 猪笼草捕虫囊蛋白酶降低乳清蛋白致敏性的应用及方法

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JPH1149697A (ja) 1997-08-01 1999-02-23 Nisshin Flour Milling Co Ltd ストレス抑制剤及びストレス抑制用食品
DE19980245D2 (de) 1998-02-23 2001-05-10 Keller Helmut Verwendung eines Preßsaftes, Verdauungssaftes oder Extraktes von fleischfressenden Pflanzen zur Hemmung von Proteinkinasen
FI980410A0 (fi) 1998-02-23 1998-02-23 Tapio Raivio Termoset
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US7320788B2 (en) * 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
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Also Published As

Publication number Publication date
DK3220946T3 (da) 2021-08-02
EP3220946A1 (en) 2017-09-27
JP7369893B2 (ja) 2023-10-27
US10960059B2 (en) 2021-03-30
JP2017519763A (ja) 2017-07-20
EP3943104A1 (en) 2022-01-26
US20210220451A1 (en) 2021-07-22
EP3220946A4 (en) 2018-08-15
JP6829077B2 (ja) 2021-02-10
WO2015192211A1 (en) 2015-12-23
CN106794228B (zh) 2021-09-03
US20160022785A1 (en) 2016-01-28
US20190022194A1 (en) 2019-01-24
ES2883347T3 (es) 2021-12-07
WO2015192211A9 (en) 2016-02-25
CN106794228A (zh) 2017-05-31
CN113827708A (zh) 2021-12-24
EP3220946B1 (en) 2021-06-09
US11723960B2 (en) 2023-08-15
JP2021073236A (ja) 2021-05-13

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