SI2856152T1 - Novi biomarkerji za oceno tveganja odpovedi alografta in smrtnosti bolnika po presaditvi organa - Google Patents

Novi biomarkerji za oceno tveganja odpovedi alografta in smrtnosti bolnika po presaditvi organa

Info

Publication number
SI2856152T1
SI2856152T1 SI201331932T SI201331932T SI2856152T1 SI 2856152 T1 SI2856152 T1 SI 2856152T1 SI 201331932 T SI201331932 T SI 201331932T SI 201331932 T SI201331932 T SI 201331932T SI 2856152 T1 SI2856152 T1 SI 2856152T1
Authority
SI
Slovenia
Prior art keywords
estimate
risk
organ transplantation
new biomarkers
patient mortality
Prior art date
Application number
SI201331932T
Other languages
English (en)
Inventor
Cornelis Vermeer
Borst Martin De
Original Assignee
Nattopharma Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattopharma Asa filed Critical Nattopharma Asa
Publication of SI2856152T1 publication Critical patent/SI2856152T1/sl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/10Post-translational modifications [PTMs] in chemical analysis of biological material acylation, e.g. acetylation, formylation, lipoylation, myristoylation, palmitoylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201331932T 2012-06-04 2013-06-04 Novi biomarkerji za oceno tveganja odpovedi alografta in smrtnosti bolnika po presaditvi organa SI2856152T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12170756.6A EP2671574A1 (en) 2012-06-04 2012-06-04 Use of vitamin K to decrease allograft failure and patient mortality after organ transplantation
EP13729629.9A EP2856152B1 (en) 2012-06-04 2013-06-04 New biomarkers to estimate the risk of allograft failure and patient mortality after organ transplantation
PCT/EP2013/061519 WO2013182579A1 (en) 2012-06-04 2013-06-04 New biomarkers to estimate the risk of allograft failure and patient mortality after organ transplantation

Publications (1)

Publication Number Publication Date
SI2856152T1 true SI2856152T1 (sl) 2022-01-31

Family

ID=48651994

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331932T SI2856152T1 (sl) 2012-06-04 2013-06-04 Novi biomarkerji za oceno tveganja odpovedi alografta in smrtnosti bolnika po presaditvi organa

Country Status (11)

Country Link
US (2) US20150141386A1 (sl)
EP (3) EP2671574A1 (sl)
DK (1) DK2856152T3 (sl)
ES (1) ES2891249T3 (sl)
HR (1) HRP20211676T1 (sl)
HU (1) HUE056601T2 (sl)
LT (1) LT2856152T (sl)
PL (1) PL2856152T3 (sl)
PT (1) PT2856152T (sl)
SI (1) SI2856152T1 (sl)
WO (2) WO2013182578A1 (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016131993A2 (en) * 2015-02-20 2016-08-25 Vitak B.V. Vitamin k and capillary function

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635478A (en) * 1989-09-18 1997-06-03 Yale University Use of calcitonin gene-related peptide to regulate immune response
WO2000008495A2 (en) * 1998-08-06 2000-02-17 University Of Pittsburgh Of The Commonwealth System Of Higher Education Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof
WO2001002863A1 (en) 1999-07-04 2001-01-11 Cardiovascular Research Institute Maastricht (Carim) Diagnostic assay for human matrix gla-protein and its use as a biomarker
US7700296B2 (en) 1999-07-04 2010-04-20 Mgp Diagnostics As Diagnostic assay for human Matrix Gla-protein and its use as a biomarker
ATE361001T1 (de) 2000-05-12 2007-05-15 Vitak Bv Nahrungsmittel enthaltend vitamin k2
WO2004108748A2 (en) * 2002-09-24 2004-12-16 Dow, Kenneth, Centocor, Inc. Growth arrest specific gene 6 peptides, antibodies, compositions, methods and uses
WO2005054503A2 (en) * 2003-12-03 2005-06-16 Novartis Ag Biomarkers for graft rejection
WO2005107731A1 (ja) * 2004-05-12 2005-11-17 Eisai R & D Management Co., Ltd. ビタミンk2を有効成分として含む治療剤
RU2318500C2 (ru) * 2005-10-18 2008-03-10 Общество С Ограниченной Ответственностью "Митотехнология" Способ воздействия на организм путем адресной доставки биологически активных веществ в митохондрии, фармацевтическая композиция для его осуществления и соединение, применяемое для этой цели
WO2008147283A1 (en) * 2007-05-25 2008-12-04 Leif Salford The use of zeburaline for the treatment of autoimmune diseases or immune rejection of transplants
EP2595615A1 (en) * 2010-07-19 2013-05-29 Summa Health System Vitamin c and chromium-free vitamin k, and compositions thereof for treating an nfkb-mediated condition or disease

Also Published As

Publication number Publication date
WO2013182579A1 (en) 2013-12-12
US20150141386A1 (en) 2015-05-21
EP2854788A1 (en) 2015-04-08
LT2856152T (lt) 2021-12-10
US20150153352A1 (en) 2015-06-04
DK2856152T3 (da) 2021-11-01
ES2891249T3 (es) 2022-01-26
EP2671574A1 (en) 2013-12-11
HRP20211676T1 (hr) 2022-02-18
PT2856152T (pt) 2021-09-29
HUE056601T2 (hu) 2022-02-28
PL2856152T3 (pl) 2022-02-07
EP2856152B1 (en) 2021-08-04
EP2856152A1 (en) 2015-04-08
WO2013182578A1 (en) 2013-12-12

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