SI2751081T1 - Polimorfna oblika kalcijevega pitavastatinata - Google Patents

Polimorfna oblika kalcijevega pitavastatinata

Info

Publication number
SI2751081T1
SI2751081T1 SI201230918A SI201230918A SI2751081T1 SI 2751081 T1 SI2751081 T1 SI 2751081T1 SI 201230918 A SI201230918 A SI 201230918A SI 201230918 A SI201230918 A SI 201230918A SI 2751081 T1 SI2751081 T1 SI 2751081T1
Authority
SI
Slovenia
Prior art keywords
polymorphic form
pitavastatin calcium
pitavastatin
calcium
polymorphic
Prior art date
Application number
SI201230918A
Other languages
English (en)
Inventor
Alen Kljajic
Sabina Trost
Anica Pecavar
Rok Zupet
Original Assignee
Farma Grs, D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farma Grs, D.O.O. filed Critical Farma Grs, D.O.O.
Publication of SI2751081T1 publication Critical patent/SI2751081T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0036—Crystallisation on to a bed of product crystals; Seeding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201230918A 2011-09-12 2012-09-12 Polimorfna oblika kalcijevega pitavastatinata SI2751081T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201100359 2011-09-12
PCT/EP2012/067859 WO2013037838A1 (en) 2011-09-12 2012-09-12 Polymorphic form of pitavastatin calcium
EP12756750.1A EP2751081B1 (en) 2011-09-12 2012-09-12 Polymorphic form of pitavastatin calcium

Publications (1)

Publication Number Publication Date
SI2751081T1 true SI2751081T1 (sl) 2017-05-31

Family

ID=46829784

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230918A SI2751081T1 (sl) 2011-09-12 2012-09-12 Polimorfna oblika kalcijevega pitavastatinata

Country Status (6)

Country Link
EP (1) EP2751081B1 (sl)
EA (1) EA024991B1 (sl)
ES (1) ES2620968T3 (sl)
PT (1) PT2751081T (sl)
SI (1) SI2751081T1 (sl)
WO (1) WO2013037838A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105189458A (zh) * 2013-03-29 2015-12-23 中化帝斯曼制药有限公司荷兰公司 匹伐他汀和罗素伐他汀的胺盐
US10629442B2 (en) 2013-10-14 2020-04-21 Orbotech Ltd. Lift printing of multi-composition material structures
WO2016063270A1 (en) 2014-10-19 2016-04-28 Orbotech Ltd. Llift printing of conductive traces onto a semiconductor substrate
EP3247816A4 (en) 2015-01-19 2018-01-24 Orbotech Ltd. Printing of three-dimensional metal structures with a sacrificial support
US10688692B2 (en) 2015-11-22 2020-06-23 Orbotech Ltd. Control of surface properties of printed three-dimensional structures
CN107115306B (zh) * 2017-04-17 2019-09-13 浙江京新药业股份有限公司 一种含匹伐他汀钙的药物组合物及其制备方法
TW201901887A (zh) 2017-05-24 2019-01-01 以色列商奧寶科技股份有限公司 於未事先圖樣化基板上電器互連電路元件

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336714C (en) 1987-08-20 1995-08-15 Yoshihiro Fujikawa Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
JP3528186B2 (ja) 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
CN102285916B (zh) * 2003-02-12 2015-02-25 日产化学工业株式会社 匹伐他汀钙的晶形
TWI328006B (en) 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
WO2007132482A2 (en) * 2006-05-17 2007-11-22 Manne Satyanarayana Reddy Novel process for the preparation of pitavastatin and its pharmaceutically acceptable salts
CN101195603A (zh) 2007-11-21 2008-06-11 重庆医药工业研究院有限责任公司 一种匹伐他汀钙的新晶型及其制备方法
WO2010089770A2 (en) 2009-01-19 2010-08-12 Msn Laboratories Limited Improved process for the preparation of highly pure (3r,5s)-7-[2-cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxy-6(e)-heptenoic acid and pharmaceutically acceptable salts thereof
KR20100125124A (ko) 2009-05-20 2010-11-30 미래파인켐 주식회사 피타바스타틴 헤미칼슘염의 신규한 결정형 및 그의 제조방법
WO2011089623A2 (en) 2010-01-20 2011-07-28 Cadila Healthcare Limited Process for preparing pitavastatin and pharmaceutically acceptable salts thereof
KR101134021B1 (ko) * 2010-02-24 2012-04-05 주식회사 메디켐코리아 새로운 중간체를 이용하는 피타바스타틴 헤미칼슘의 신규한 제조방법
EP2638013A4 (en) * 2010-11-12 2014-03-26 Hetero Research Foundation NEW POLYMORPHS OF CALCIUM PIVASTATIN

Also Published As

Publication number Publication date
EP2751081B1 (en) 2017-01-04
PT2751081T (pt) 2017-04-04
EP2751081A1 (en) 2014-07-09
EA201490578A1 (ru) 2015-01-30
EA024991B1 (ru) 2016-11-30
ES2620968T3 (es) 2017-06-30
WO2013037838A1 (en) 2013-03-21

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