SI2736487T1 - Nove formulacije (trimetoksifenilamino)pirimidinila - Google Patents

Nove formulacije (trimetoksifenilamino)pirimidinila

Info

Publication number
SI2736487T1
SI2736487T1 SI201231519T SI201231519T SI2736487T1 SI 2736487 T1 SI2736487 T1 SI 2736487T1 SI 201231519 T SI201231519 T SI 201231519T SI 201231519 T SI201231519 T SI 201231519T SI 2736487 T1 SI2736487 T1 SI 2736487T1
Authority
SI
Slovenia
Prior art keywords
trimethoxyphenylamino
pyrimidinyl
formulations
new
pyrimidinyl formulations
Prior art date
Application number
SI201231519T
Other languages
English (en)
Inventor
Farhan Abdul Karim Alhusban
Ian Paul Gabbott
Bindhumadhavan Gururajan
Dawn Sievwright
David Bradley Brook Simpson
Original Assignee
Rigel Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46875902&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2736487(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals, Inc. filed Critical Rigel Pharmaceuticals, Inc.
Publication of SI2736487T1 publication Critical patent/SI2736487T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI201231519T 2011-07-28 2012-07-26 Nove formulacije (trimetoksifenilamino)pirimidinila SI2736487T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161512621P 2011-07-28 2011-07-28
EP12759802.7A EP2736487B1 (en) 2011-07-28 2012-07-26 New (trimethoxyphenylamino)pyrimidinyl formulations
PCT/GB2012/051791 WO2013014454A1 (en) 2011-07-28 2012-07-26 New (trimethoxyphenylamino)pyrimidinyl formulations

Publications (1)

Publication Number Publication Date
SI2736487T1 true SI2736487T1 (sl) 2019-04-30

Family

ID=46875902

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231519T SI2736487T1 (sl) 2011-07-28 2012-07-26 Nove formulacije (trimetoksifenilamino)pirimidinila

Country Status (26)

Country Link
US (2) US8771648B2 (sl)
EP (1) EP2736487B1 (sl)
JP (1) JP6019116B2 (sl)
KR (2) KR102024120B1 (sl)
CN (1) CN103826610B (sl)
AR (1) AR087371A1 (sl)
AU (1) AU2012288632B2 (sl)
BR (1) BR112014001999B1 (sl)
CA (1) CA2843138C (sl)
CY (1) CY1122596T1 (sl)
DK (1) DK2736487T3 (sl)
EA (1) EA028432B1 (sl)
ES (1) ES2710423T3 (sl)
HK (1) HK1198741A1 (sl)
HR (1) HRP20190186T1 (sl)
HU (1) HUE042611T2 (sl)
LT (1) LT2736487T (sl)
MX (1) MX339685B (sl)
PL (1) PL2736487T3 (sl)
PT (1) PT2736487T (sl)
RS (1) RS58433B1 (sl)
SI (1) SI2736487T1 (sl)
TR (1) TR201901792T4 (sl)
TW (1) TW201311251A (sl)
UY (1) UY34223A (sl)
WO (1) WO2013014454A1 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2078026T3 (da) * 2006-11-21 2012-04-30 Rigel Pharmaceuticals Inc Prodrug-salte af 2, 4-pyrimidinediamine-forbindelser og anvendelser deraf
EA028432B1 (ru) 2011-07-28 2017-11-30 Райджел Фармасьютикалз, Инк. Новые составы на основе (триметоксифениламино)пиримидинилов
WO2016157141A1 (en) 2015-04-02 2016-10-06 Stora Enso Oyj An activated lignin composition, a method for the manufacturing thereof and use thereof
WO2016172053A1 (en) 2015-04-24 2016-10-27 Rigel Pharmaceuticals, Inc. Methods of treating ibrutinib-resistant disease
JP2023534913A (ja) * 2020-07-24 2023-08-15 ディーエスエム アイピー アセッツ ビー.ブイ. 新規な速溶錠

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
SG176311A1 (en) 2002-07-29 2011-12-29 Rigel Pharmaceuticals Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
CN102358738A (zh) 2003-07-30 2012-02-22 里格尔药品股份有限公司 2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途
ATE506953T1 (de) 2003-08-07 2011-05-15 Rigel Pharmaceuticals Inc 2,4-pyrimidindiamin-verbindungen und verwendungen als antiproliferative mittel
US20060051406A1 (en) * 2004-07-23 2006-03-09 Manjeet Parmar Formulation of insoluble small molecule therapeutics in lipid-based carriers
AU2005289426A1 (en) * 2004-09-27 2006-04-06 Amgen Inc. Substituted heterocyclic compounds and methods of use
CA2591948C (en) * 2005-01-19 2013-11-12 Rigel Pharmaceuticals, Inc. Prodrugs of 2,4-pyrimidinediamine compounds and their uses
US8227455B2 (en) 2005-04-18 2012-07-24 Rigel Pharmaceuticals, Inc. Methods of treating cell proliferative disorders
US8246984B2 (en) * 2005-12-06 2012-08-21 Rigel Pharmaceuticals, Inc. Formulation of insoluble small molecule therapeutics in lipid-based carriers
WO2007120980A2 (en) * 2006-02-17 2007-10-25 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
US20090048214A1 (en) * 2006-11-15 2009-02-19 Rigel Pharmaceuticals, Inc Methods for Treating Renal Tumors Using 2, 4-Pyrimidinediamine Drug and Prodrug Compounds
DK2078026T3 (da) * 2006-11-21 2012-04-30 Rigel Pharmaceuticals Inc Prodrug-salte af 2, 4-pyrimidinediamine-forbindelser og anvendelser deraf
US20090012045A1 (en) * 2007-06-26 2009-01-08 Rigel Pharmaceuticals, Inc. Methods of Treating Cell Proliferative Disorders
US20090088371A1 (en) * 2007-08-28 2009-04-02 Rigel Pharmaceuticals, Inc. Combination therapy with syk kinase inhibitor
SG185961A1 (en) * 2007-11-07 2012-12-28 Rigel Pharmaceuticals Inc Wet granulation using a water sequestering agent
PL2252300T3 (pl) 2008-02-22 2017-04-28 Rigel Pharmaceuticals, Inc. Zastosowanie 2,4-pirymidynodiamin do leczenia miażdżycy
UA108077C2 (xx) 2009-07-02 2015-03-25 Синтез динатрієвої солі n4-(2,2-диметил-4-$(дигідрофосфонокси)метил]-3-оксо-5-піридо$1,4]оксазин-6-іл)-5-фтор-n2-(3,4,5-триметоксифеніл)-2,4-піримідиндіаміну
JP2012533567A (ja) 2009-07-17 2012-12-27 ライジェル ファーマシューティカルズ, インコーポレイテッド 重水素化2,4−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用
US8389515B2 (en) 2009-11-20 2013-03-05 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds and prodrugs and their uses
EP2558474B1 (en) 2010-04-13 2015-11-25 Rigel Pharmaceuticals, Inc. 2, 4-pyrimidinediamine compounds and prodrugs thereof and their uses
EA028432B1 (ru) 2011-07-28 2017-11-30 Райджел Фармасьютикалз, Инк. Новые составы на основе (триметоксифениламино)пиримидинилов

Also Published As

Publication number Publication date
HK1198741A1 (en) 2015-06-05
JP2014521630A (ja) 2014-08-28
AU2012288632A1 (en) 2014-02-20
BR112014001999B1 (pt) 2023-11-28
EA028432B1 (ru) 2017-11-30
DK2736487T3 (en) 2019-03-04
HUE042611T2 (hu) 2019-07-29
MX2014001065A (es) 2014-08-01
EA201490363A1 (ru) 2014-06-30
EP2736487B1 (en) 2018-11-07
CN103826610B (zh) 2017-08-04
TR201901792T4 (tr) 2019-03-21
EP2736487A1 (en) 2014-06-04
BR112014001999A2 (pt) 2017-02-21
PT2736487T (pt) 2019-02-13
KR102090440B1 (ko) 2020-03-17
KR102024120B1 (ko) 2019-09-23
WO2013014454A1 (en) 2013-01-31
CA2843138A1 (en) 2013-01-31
RS58433B1 (sr) 2019-04-30
KR20140058576A (ko) 2014-05-14
CN103826610A (zh) 2014-05-28
AU2012288632B2 (en) 2017-08-17
US20130058876A1 (en) 2013-03-07
AR087371A1 (es) 2014-03-19
US8771648B2 (en) 2014-07-08
MX339685B (es) 2016-06-06
ES2710423T3 (es) 2019-04-25
HRP20190186T1 (hr) 2019-03-22
US8951504B2 (en) 2015-02-10
CY1122596T1 (el) 2021-01-27
US20140271493A1 (en) 2014-09-18
JP6019116B2 (ja) 2016-11-02
LT2736487T (lt) 2019-02-25
PL2736487T3 (pl) 2019-06-28
KR20190109576A (ko) 2019-09-25
CA2843138C (en) 2020-06-02
TW201311251A (zh) 2013-03-16
UY34223A (es) 2013-02-28

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