SI2723320T1 - Tekoča farmacevtska sestava, ki obsega nitizinon - Google Patents

Tekoča farmacevtska sestava, ki obsega nitizinon

Info

Publication number
SI2723320T1
SI2723320T1 SI201230504A SI201230504A SI2723320T1 SI 2723320 T1 SI2723320 T1 SI 2723320T1 SI 201230504 A SI201230504 A SI 201230504A SI 201230504 A SI201230504 A SI 201230504A SI 2723320 T1 SI2723320 T1 SI 2723320T1
Authority
SI
Slovenia
Prior art keywords
nitisinone
pharmaceutical composition
liquid pharmaceutical
liquid
composition
Prior art date
Application number
SI201230504A
Other languages
English (en)
Inventor
Lennart Svensson
Hans Siden
Original Assignee
Swedish Orphan Biovitrum International Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum International Ab filed Critical Swedish Orphan Biovitrum International Ab
Publication of SI2723320T1 publication Critical patent/SI2723320T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
SI201230504A 2011-06-23 2012-06-20 Tekoča farmacevtska sestava, ki obsega nitizinon SI2723320T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1150585 2011-06-23
EP12802262.1A EP2723320B1 (en) 2011-06-23 2012-06-20 Liquid pharmaceutical composition comprising nitisinone
PCT/SE2012/050681 WO2012177214A1 (en) 2011-06-23 2012-06-20 Liquid pharmaceutical composition comprising nitisinone

Publications (1)

Publication Number Publication Date
SI2723320T1 true SI2723320T1 (sl) 2016-05-31

Family

ID=47422827

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230504A SI2723320T1 (sl) 2011-06-23 2012-06-20 Tekoča farmacevtska sestava, ki obsega nitizinon

Country Status (22)

Country Link
US (2) US9301932B2 (sl)
EP (1) EP2723320B1 (sl)
JP (1) JP6038132B2 (sl)
CN (1) CN103747781B (sl)
AU (1) AU2012273515B2 (sl)
BR (1) BR112013033008B1 (sl)
CA (1) CA2838039C (sl)
CL (1) CL2013003630A1 (sl)
CY (1) CY1117273T1 (sl)
DK (1) DK2723320T3 (sl)
ES (1) ES2566787T3 (sl)
HR (1) HRP20160286T1 (sl)
HU (1) HUE027304T2 (sl)
IL (1) IL229677A (sl)
MX (1) MX2013014567A (sl)
PL (1) PL2723320T3 (sl)
RS (1) RS54632B1 (sl)
RU (1) RU2605301C2 (sl)
SI (1) SI2723320T1 (sl)
SM (1) SMT201600097B (sl)
UA (1) UA110979C2 (sl)
WO (1) WO2012177214A1 (sl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012273515B2 (en) * 2011-06-23 2016-11-03 Swedish Orphan Biovitrum International Ab Liquid pharmaceutical composition comprising nitisinone
WO2013181292A1 (en) * 2012-05-29 2013-12-05 Biotie Therapies, Inc. Nitisinone formulations
BR112016024756A2 (pt) * 2014-04-30 2017-08-15 Swedish Orphan Biovitrum Int Ab regimes de dosagem de nitisinona para o tratamento da alcaptonúria
CN104623428A (zh) * 2015-03-13 2015-05-20 庄彩梅 一种缓解遗传性酪氨酸血症的中药制剂及其制备方法
ITUB20160650A1 (it) 2016-02-11 2017-08-11 Dipharma S A Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione
ITUB20160972A1 (it) * 2016-02-23 2017-08-23 Univ Degli Studi Di Siena Trattamento dell’alkaptonuria e della tirosinemia di tipo 1
CN110464716A (zh) * 2019-09-03 2019-11-19 黄嘉若 一种尼替西农在制备治疗肺癌药物中的用途
CN112107548A (zh) * 2020-10-30 2020-12-22 兆科药业(广州)有限公司 一种含有尼替西农的药物组合物及其制备方法
CN114831974A (zh) * 2022-06-23 2022-08-02 徐州医科大学 尼替西农在制备预防和治疗内毒素性休克疾病药物中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006158A (en) 1984-12-20 1991-04-09 Ici Americas Inc. Certain 2-(2-substituted benzoyl)-1,3-cyclohexanediones
US4695673A (en) 1985-11-20 1987-09-22 Stauffer Chemical Company Process for the production of acylated 1,3-dicarbonyl compounds
DE69228813T2 (de) * 1991-06-24 1999-08-05 Zeneca Ltd Verwendung von 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyclohexandion zur behandlung von tyrosinämie sowie pharmazeutische zusammensetzungen
US5668089A (en) 1996-04-08 1997-09-16 Zeneca Limited Selective corn herbicide
AU2003249741A1 (en) * 2002-07-03 2004-01-23 Hartmut M. Hanauske-Abel Methods of inhibiting 4-hydroxyphenylpyruvate dioxygenase in a living system
GB0405760D0 (en) 2004-03-15 2004-04-21 Syngenta Participations Ag Agrochemical formulation
GB0414895D0 (en) 2004-07-02 2004-08-04 Syngenta Ltd Herbicidal formulation
GB0504103D0 (en) * 2005-02-28 2005-04-06 Syngenta Ltd Novel method
US20100305095A1 (en) 2006-08-18 2010-12-02 Kim Zachary Travis Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs
CA2742841A1 (en) * 2008-11-06 2010-05-14 Biotie Therapies, Inc. Treatment of restless leg syndrome and sleep disorders
US8354451B2 (en) * 2009-03-09 2013-01-15 The Uwm Research Foundation, Inc. Treatment of microbial infections with compounds that inhibit 4-hydroxyphenylpyruvate dioxygenase
AU2012273515B2 (en) * 2011-06-23 2016-11-03 Swedish Orphan Biovitrum International Ab Liquid pharmaceutical composition comprising nitisinone
WO2013181292A1 (en) * 2012-05-29 2013-12-05 Biotie Therapies, Inc. Nitisinone formulations

Also Published As

Publication number Publication date
SMT201600097B (it) 2016-04-29
BR112013033008B1 (pt) 2021-05-18
HRP20160286T1 (hr) 2016-05-06
MX2013014567A (es) 2014-08-21
AU2012273515A1 (en) 2013-12-12
BR112013033008A8 (pt) 2018-03-06
CL2013003630A1 (es) 2014-11-21
US20140206771A1 (en) 2014-07-24
AU2012273515B2 (en) 2016-11-03
RS54632B1 (en) 2016-08-31
NZ618332A (en) 2015-06-26
JP6038132B2 (ja) 2016-12-07
PL2723320T3 (pl) 2016-06-30
EP2723320B1 (en) 2016-01-13
UA110979C2 (uk) 2016-03-10
WO2012177214A1 (en) 2012-12-27
DK2723320T3 (en) 2016-03-21
HUE027304T2 (en) 2016-10-28
BR112013033008A2 (pt) 2017-01-31
EP2723320A1 (en) 2014-04-30
JP2014517067A (ja) 2014-07-17
US9301932B2 (en) 2016-04-05
CN103747781A (zh) 2014-04-23
IL229677A0 (en) 2014-01-30
CY1117273T1 (el) 2017-04-26
IL229677A (en) 2017-03-30
RU2605301C2 (ru) 2016-12-20
RU2014101990A (ru) 2015-07-27
CN103747781B (zh) 2018-06-08
CA2838039A1 (en) 2012-12-27
US20150174081A1 (en) 2015-06-25
CA2838039C (en) 2017-10-24
ES2566787T3 (es) 2016-04-15
EP2723320A4 (en) 2014-12-03

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