SI2671884T1 - Novi derivati 6,11-dihidro-5H-benzo(d)imidazo(1,2-a)azepinov kot ligandi receptorjev histamina H4 - Google Patents
Novi derivati 6,11-dihidro-5H-benzo(d)imidazo(1,2-a)azepinov kot ligandi receptorjev histamina H4Info
- Publication number
- SI2671884T1 SI2671884T1 SI201330042T SI201330042T SI2671884T1 SI 2671884 T1 SI2671884 T1 SI 2671884T1 SI 201330042 T SI201330042 T SI 201330042T SI 201330042 T SI201330042 T SI 201330042T SI 2671884 T1 SI2671884 T1 SI 2671884T1
- Authority
- SI
- Slovenia
- Prior art keywords
- imidazo
- histamine
- benzo
- dihydro
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305633.5A EP2671883A1 (en) | 2012-06-05 | 2012-06-05 | New 6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands |
| EP13170666.5A EP2671884B1 (en) | 2012-06-05 | 2013-06-05 | New 6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2671884T1 true SI2671884T1 (sl) | 2015-07-31 |
Family
ID=48534298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201330042T SI2671884T1 (sl) | 2012-06-05 | 2013-06-05 | Novi derivati 6,11-dihidro-5H-benzo(d)imidazo(1,2-a)azepinov kot ligandi receptorjev histamina H4 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9255101B2 (sl) |
| EP (2) | EP2671883A1 (sl) |
| CY (1) | CY1116563T1 (sl) |
| DK (1) | DK2671884T3 (sl) |
| ES (1) | ES2540976T3 (sl) |
| HR (1) | HRP20150673T1 (sl) |
| PL (1) | PL2671884T3 (sl) |
| PT (1) | PT2671884E (sl) |
| RS (1) | RS54080B1 (sl) |
| SI (1) | SI2671884T1 (sl) |
| SM (1) | SMT201500221B (sl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
| US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
| CA2929545C (en) | 2009-05-01 | 2019-04-09 | Aerie Pharmaceuticals, Inc. | Dual mechanism inhibitors for the treatment of disease |
| PL3811943T3 (pl) | 2013-03-15 | 2023-06-12 | Aerie Pharmaceuticals, Inc. | Związek do stosowania w leczeniu zaburzeń oczu |
| CA2990991A1 (en) | 2015-07-24 | 2017-02-02 | Basf Se | Pyridine compounds useful for combating phytopathogenic fungi |
| ES2767693T3 (es) | 2015-09-03 | 2020-06-18 | Basf Agro Bv | Composiciones de micropartículas que comprenden saflufenacilo |
| EP3359530A1 (en) | 2015-10-05 | 2018-08-15 | Basf Se | Pyridine derivatives for combating phytopathogenic fungi |
| US9643927B1 (en) * | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
| US11389441B2 (en) | 2016-08-31 | 2022-07-19 | Aerie Pharmaceuticals, Inc. | Ophthalmic compositions |
| WO2018054723A1 (en) | 2016-09-26 | 2018-03-29 | Basf Se | Pyridine compounds for controlling phytopathogenic harmful fungi |
| WO2018054721A1 (en) | 2016-09-26 | 2018-03-29 | Basf Se | Pyridine compounds for controlling phytopathogenic harmful fungi |
| WO2018054711A1 (en) | 2016-09-26 | 2018-03-29 | Basf Se | Pyridine compounds for controlling phytopathogenic harmful fungi |
| WO2018065182A1 (en) | 2016-10-04 | 2018-04-12 | Basf Se | Reduced quinoline compounds as antifuni agents |
| WO2018073110A1 (en) | 2016-10-20 | 2018-04-26 | Basf Se | Quinoline compounds as fungicides |
| CN106632061B (zh) * | 2016-11-23 | 2020-07-24 | 上海皓元医药股份有限公司 | 一种1-(4-苯基-1-烷基-1h-咪唑-2-基)乙酮及其衍生物的合成方法 |
| WO2018134127A1 (en) | 2017-01-23 | 2018-07-26 | Basf Se | Fungicidal pyridine compounds |
| JP2020515583A (ja) | 2017-03-31 | 2020-05-28 | アエリエ ファーマシューティカルズ インコーポレイテッド | アリールシクロプロピル−アミノ−イソキノリニルアミド化合物 |
| CN110475772A (zh) | 2017-04-06 | 2019-11-19 | 巴斯夫欧洲公司 | 吡啶化合物 |
| EP3723485A1 (en) | 2017-12-15 | 2020-10-21 | Basf Se | Fungicidal mixture comprising substituted pyridines |
| CA3112391A1 (en) | 2018-09-14 | 2020-03-19 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
| CN112876436B (zh) * | 2021-03-01 | 2022-06-21 | 安徽金轩科技有限公司 | 一种高选择性制备呋喃铵盐的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007272956B2 (en) | 2006-07-11 | 2013-05-02 | Janssen Pharmaceutica, N.V. | Benzofuro-and benzothienopyryimidine modulators of the histamine H4 receptor |
-
2012
- 2012-06-05 EP EP12305633.5A patent/EP2671883A1/en not_active Withdrawn
-
2013
- 2013-06-05 SI SI201330042T patent/SI2671884T1/sl unknown
- 2013-06-05 PT PT131706665T patent/PT2671884E/pt unknown
- 2013-06-05 RS RS20150426A patent/RS54080B1/en unknown
- 2013-06-05 DK DK13170666.5T patent/DK2671884T3/en active
- 2013-06-05 EP EP13170666.5A patent/EP2671884B1/en active Active
- 2013-06-05 PL PL13170666T patent/PL2671884T3/pl unknown
- 2013-06-05 US US13/910,475 patent/US9255101B2/en active Active
- 2013-06-05 ES ES13170666.5T patent/ES2540976T3/es active Active
-
2015
- 2015-06-19 HR HRP20150673TT patent/HRP20150673T1/hr unknown
- 2015-06-23 CY CY20151100536T patent/CY1116563T1/el unknown
- 2015-09-18 SM SM201500221T patent/SMT201500221B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9255101B2 (en) | 2016-02-09 |
| HRP20150673T1 (hr) | 2015-07-31 |
| PT2671884E (pt) | 2015-07-30 |
| DK2671884T3 (en) | 2015-06-29 |
| EP2671883A1 (en) | 2013-12-11 |
| SMT201500221B (it) | 2015-10-30 |
| RS54080B1 (en) | 2015-10-30 |
| CY1116563T1 (el) | 2017-03-15 |
| PL2671884T3 (pl) | 2015-08-31 |
| EP2671884B1 (en) | 2015-03-25 |
| US20130324506A1 (en) | 2013-12-05 |
| ES2540976T3 (es) | 2015-07-15 |
| EP2671884A1 (en) | 2013-12-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2671884T1 (sl) | Novi derivati 6,11-dihidro-5H-benzo(d)imidazo(1,2-a)azepinov kot ligandi receptorjev histamina H4 | |
| IL234485A (en) | Compounds based on imidazo [2,1 – b] pyridazine | |
| ZA201704808B (en) | Cytotoxic benzodiazepine derivatives | |
| HRP20171724T1 (hr) | Imidazo[1,2-b]piridazin derivati kao inhibitori kinaze | |
| HK1211208A1 (en) | Cytotoxic benzodiazepine derivatives | |
| IL227496B (en) | Pyrazolo[4,3–b]pyridines are converted as drugs | |
| ZA201307783B (en) | Tri-and tetracylic pyrazolo[3,4-b]pyridine compounds as antineoplastic agent | |
| EP2935264A4 (en) | BICYCLIC 1,4-PYRIDONE HETEROARYL COMPOUNDS | |
| EP2935214A4 (en) | 1,4-PYRIDONES COMPOUNDS | |
| EP2887807A4 (en) | NOVEL DERIVATIVES OF BENZIMIDAZOLE HEXAHYDROFURO [3,2-B] FURANE | |
| ZA201206630B (en) | Hetaryl-[1,8]naphthyridine derivatives | |
| IL232717A0 (en) | 3-cyanoaryl-h1-pyrrolo[b-3,2]pyridine derivatives | |
| ZA201507389B (en) | 2-phenyl or 2-hetaryl imidazol[1,2-a]pyridine derivatives | |
| IL260298B (en) | 6,7,8,9-tetrahydro-5h-pyrido[2,3-d]azepine dopamine d3 ligands | |
| HK1183867A1 (en) | Benzazole derivatives as histamine h4 receptor ligands h4 | |
| EP2970278A4 (en) | Pyrrolo [2,3] PYRIDINE KINASE INHIBITORS CDK9- | |
| EP2565194A4 (en) | Imidazo [1,2-A] pyridine | |
| IL236473B (en) | 1, 5-dihydro-2-pyrrole-one derivatives as cholecystokinin receptor ligands | |
| HK1208029A1 (en) | Imidazopyridine derivatives | |
| HK1214244A1 (zh) | 咪唑並吡啶衍生物 | |
| IL235300A0 (en) | A process for the preparation of naphthyridine hist | |
| IL230889A0 (en) | 1, -diazabicyclo[2.2.3]nonanes as ligands for the neuronal nicotinic acetylcholine receptor | |
| ZA201505135B (en) | Cytotoxic benzodiazepine derivatives | |
| GB201221462D0 (en) | Novel isothiazolo[5,4-b]pyridines | |
| GB201213663D0 (en) | Novel isothiazolo[5,4-b]pyridines |