SI2611415T1 - Agonisti adenosina A1 za zdravljenje glavkoma in očesne hipertenzije - Google Patents

Agonisti adenosina A1 za zdravljenje glavkoma in očesne hipertenzije

Info

Publication number
SI2611415T1
SI2611415T1 SI201130809A SI201130809A SI2611415T1 SI 2611415 T1 SI2611415 T1 SI 2611415T1 SI 201130809 A SI201130809 A SI 201130809A SI 201130809 A SI201130809 A SI 201130809A SI 2611415 T1 SI2611415 T1 SI 2611415T1
Authority
SI
Slovenia
Prior art keywords
glaucoma
adenosine
agonists
treatment
ocular hypertension
Prior art date
Application number
SI201130809A
Other languages
English (en)
Inventor
Jurgen Klar
Degenfeld Georges Von
Hans-Georg Lerchen
Barbara Albrecht-Kupper
Andreas Knorr
Peter Sandner
Daniel Meibom
Original Assignee
Bayer Intellectual Property Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Intellectual Property Gmbh filed Critical Bayer Intellectual Property Gmbh
Publication of SI2611415T1 publication Critical patent/SI2611415T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
SI201130809A 2010-09-02 2011-08-29 Agonisti adenosina A1 za zdravljenje glavkoma in očesne hipertenzije SI2611415T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10175151 2010-09-02
PCT/EP2011/064829 WO2012028585A1 (en) 2010-09-02 2011-08-29 Adenosine a1 agonists for the treatment of glaucoma and ocular hypertension
EP11752517.0A EP2611415B1 (en) 2010-09-02 2011-08-29 Adenosine a1 agonists for the treatment of glaucoma and ocular hypertension

Publications (1)

Publication Number Publication Date
SI2611415T1 true SI2611415T1 (sl) 2016-06-30

Family

ID=44582992

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201130809A SI2611415T1 (sl) 2010-09-02 2011-08-29 Agonisti adenosina A1 za zdravljenje glavkoma in očesne hipertenzije

Country Status (30)

Country Link
US (3) US20120058983A1 (sl)
EP (1) EP2611415B1 (sl)
JP (1) JP5875585B2 (sl)
KR (1) KR20140091457A (sl)
CN (1) CN103249400B (sl)
AP (1) AP3413A (sl)
AU (1) AU2011298430B2 (sl)
BR (1) BR112013005224A2 (sl)
CA (1) CA2809700A1 (sl)
CL (2) CL2013000599A1 (sl)
CR (1) CR20130094A (sl)
CY (1) CY1117458T1 (sl)
DK (1) DK2611415T3 (sl)
EA (1) EA028411B1 (sl)
ES (1) ES2570659T3 (sl)
HK (1) HK1188138A1 (sl)
HR (1) HRP20160532T1 (sl)
HU (1) HUE027295T2 (sl)
MA (1) MA34489B1 (sl)
MX (1) MX2013002396A (sl)
MY (1) MY160383A (sl)
NZ (1) NZ607624A (sl)
PL (1) PL2611415T3 (sl)
RS (1) RS54743B1 (sl)
SG (1) SG187974A1 (sl)
SI (1) SI2611415T1 (sl)
TW (1) TWI516266B (sl)
UA (1) UA111947C2 (sl)
WO (1) WO2012028585A1 (sl)
ZA (1) ZA201302340B (sl)

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US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
KR20160094974A (ko) * 2013-12-12 2016-08-10 바이엘 파마 악티엔게젤샤프트 신장 질환에 대한 의약으로서의 아데노신 a1 작용제
EP3093021B1 (en) * 2014-01-10 2021-06-02 Santen Pharmaceutical Co., Ltd. Pyridylaminoacetic acid compound and polyoxyethylene castor oil-containing pharmaceutical composition
LT3292133T (lt) * 2015-05-06 2019-08-26 Bayer Pharma Aktiengesellschaft 2-{4-[2-({[2-(4-chlorfenil)-1,3-tiazol-4-il]metil}sulfanil)-3,5-dician-6-(pirolidin-1-il)piridin-4-il]fenoksi}etil-l-alanil-l-alaninato monohidrochlorido gamybos būdas
WO2017137528A1 (en) 2016-02-12 2017-08-17 Charité - Universitätsmedizin Berlin Adenosine a1 receptor agonist for use in treatment of status epilepticus
CN112545983A (zh) * 2020-12-18 2021-03-26 合肥中龙神力动物药业有限公司 一种复方硫酸新霉素滴眼液及其制备方法和应用

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Also Published As

Publication number Publication date
SG187974A1 (en) 2013-04-30
US9040566B2 (en) 2015-05-26
UA111947C2 (uk) 2016-07-11
MX2013002396A (es) 2013-04-03
EA028411B1 (ru) 2017-11-30
US20120058983A1 (en) 2012-03-08
EP2611415A1 (en) 2013-07-10
BR112013005224A2 (pt) 2016-05-03
EP2611415B1 (en) 2016-02-24
JP2013536819A (ja) 2013-09-26
CN103249400A (zh) 2013-08-14
MA34489B1 (fr) 2013-08-01
AP2013006753A0 (en) 2013-02-28
WO2012028585A1 (en) 2012-03-08
MY160383A (en) 2017-03-15
DK2611415T3 (en) 2016-05-23
CY1117458T1 (el) 2017-04-26
NZ607624A (en) 2014-10-31
CR20130094A (es) 2013-07-01
CL2016001164A1 (es) 2016-12-23
CA2809700A1 (en) 2012-03-08
KR20140091457A (ko) 2014-07-21
RS54743B1 (sr) 2016-10-31
AP3413A (en) 2015-09-30
HRP20160532T1 (hr) 2016-06-17
HUE027295T2 (en) 2016-10-28
CL2013000599A1 (es) 2013-08-09
US20130210797A1 (en) 2013-08-15
TWI516266B (zh) 2016-01-11
ES2570659T3 (es) 2016-05-19
US20150306084A1 (en) 2015-10-29
AU2011298430A1 (en) 2013-03-21
TW201212926A (en) 2012-04-01
ZA201302340B (en) 2015-11-25
HK1188138A1 (en) 2014-04-25
JP5875585B2 (ja) 2016-03-02
EA201300310A1 (ru) 2013-08-30
AU2011298430B2 (en) 2015-02-26
CN103249400B (zh) 2015-04-22
PL2611415T3 (pl) 2016-08-31

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