SI2473172T1 - Bisfosfonat sestavki in postopki za zdravljenje srčne okvare - Google Patents

Bisfosfonat sestavki in postopki za zdravljenje srčne okvare

Info

Publication number
SI2473172T1
SI2473172T1 SI201030934T SI201030934T SI2473172T1 SI 2473172 T1 SI2473172 T1 SI 2473172T1 SI 201030934 T SI201030934 T SI 201030934T SI 201030934 T SI201030934 T SI 201030934T SI 2473172 T1 SI2473172 T1 SI 2473172T1
Authority
SI
Slovenia
Prior art keywords
methods
heart failure
treating heart
bisphosphonate compositions
bisphosphonate
Prior art date
Application number
SI201030934T
Other languages
English (en)
Inventor
Kenneth W. Lyles
Cathleen S. Colon-Emeric
Christopher M. O'connor
Richard S. Stack
Colleen Stack-D'niaye
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of SI2473172T1 publication Critical patent/SI2473172T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI201030934T 2009-09-01 2010-09-01 Bisfosfonat sestavki in postopki za zdravljenje srčne okvare SI2473172T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23879709P 2009-09-01 2009-09-01
EP10814383.5A EP2473172B1 (en) 2009-09-01 2010-09-01 Bisphosphonate compositions and methods for treating heart failure
PCT/US2010/047417 WO2011028737A2 (en) 2009-09-01 2010-09-01 Bisphosphonate compositions and methods for treating heart failure

Publications (1)

Publication Number Publication Date
SI2473172T1 true SI2473172T1 (sl) 2015-07-31

Family

ID=43649931

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030934T SI2473172T1 (sl) 2009-09-01 2010-09-01 Bisfosfonat sestavki in postopki za zdravljenje srčne okvare

Country Status (12)

Country Link
US (2) US9867838B2 (sl)
EP (1) EP2473172B1 (sl)
CN (2) CN105920023A (sl)
DK (1) DK2473172T3 (sl)
ES (1) ES2537216T3 (sl)
HR (1) HRP20150496T1 (sl)
HU (1) HUE025737T2 (sl)
PL (1) PL2473172T3 (sl)
PT (1) PT2473172E (sl)
SI (1) SI2473172T1 (sl)
SM (1) SMT201500124B (sl)
WO (1) WO2011028737A2 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
EP2780021A4 (en) * 2011-11-16 2015-08-05 Univ Duke BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING AND / OR REDUCING HEART FAILURE
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
EP4132535A4 (en) * 2020-04-06 2024-04-24 Univ Duke COMPOSITIONS AND METHODS FOR TREATING INFECTION-INDUCED CARDIOMYOPATHY

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2405254C2 (de) 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
DE3428524A1 (de) 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4639338A (en) 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
DE3770982D1 (de) 1986-04-24 1991-08-01 Fujisawa Pharmaceutical Co Diphosphonsaeure-verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel.
DE3623397A1 (de) 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5057505A (en) 1986-11-21 1991-10-15 Ciba-Geigy Corporation Substituted aminomethanediphosphonic acids and use in medicaments
IL84497A (en) 1986-11-21 1994-10-21 Ciba Geigy Ag History 2-) Imidazol-1-yl (ethane-1,1-diphosphonic acid, their preparation and pharmaceutical preparations containing them
GB8808138D0 (en) 1988-04-07 1988-05-11 Leo Pharm Prod Ltd Chemical compounds
ES2072015T3 (es) * 1990-08-21 1995-07-01 Upjohn Co Derivados del acido bisfosfonico como agente anti-artritico.
US5157027A (en) 1991-05-13 1992-10-20 E. R. Squibb & Sons, Inc. Bisphosphonate squalene synthetase inhibitors and method
HUT66379A (en) 1991-05-28 1994-11-28 Procter & Gamble Calcium, trace mineral, vitamin d and drug therapy combinations
AU670337B2 (en) 1992-11-30 1996-07-11 Novartis Ag Use of certain methanebisphosphonic acid derivatives in fracture healing
EP0600834A1 (en) 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
US5403829A (en) 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
FI92465C (fi) 1993-04-14 1994-11-25 Risto Tapani Lehtinen Menetelmä endo-osteaalisten materiaalien käsittelemiseksi
US5646134A (en) 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
GB9408775D0 (en) 1994-05-04 1994-06-22 Ciba Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
US6117856A (en) 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
DE19738005A1 (de) * 1997-08-30 1999-03-04 Bayer Ag Verwendung von substituierten 1,1-Bisphosphonaten
JP2002501757A (ja) 1998-01-29 2002-01-22 メルク エンド カムパニー インコーポレーテッド ストレス応答性キナーゼのモジュレーターの特定方法
US6984400B2 (en) 1998-07-14 2006-01-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of treating restenosis using bisphosphonate nanoparticles
WO2001049295A1 (en) 2000-01-04 2001-07-12 The Regents Of The University Of California Use of low dosage bisphosphonates to inhibit cardiac and arterial calcification
WO2001064207A2 (en) * 2000-03-01 2001-09-07 University Of South Florida Methods of modulating cell-adhesion mediated drug resistance
GB0012209D0 (en) 2000-05-19 2000-07-12 Novartis Ag Organic compounds
HU228400B1 (en) 2000-06-20 2013-03-28 Novartis Ag The use of bisphosphonates for treatment of osteoporosis
IL158273A0 (en) * 2001-05-02 2004-05-12 Novartis Ag Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer
US20030064965A1 (en) 2001-10-02 2003-04-03 Jacob Richter Method of delivering drugs to a tissue using drug-coated medical devices
US20030195171A1 (en) 2002-04-05 2003-10-16 Daifotis Anastasia G. Method for inhibiting bone resorption with an alendronate and vitamin D formulation
WO2003094851A2 (en) 2002-05-11 2003-11-20 Ilex Products, Inc. 1,1- and 1,2-bisphosphonates as apoliprotein e modulators
US20050026871A1 (en) 2002-07-17 2005-02-03 Moshe Flashner-Barak Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
PT1542700E (pt) * 2002-09-16 2012-02-01 Novartis Ag Método para prevenir ou reduzir fracturas secundárias após a fractura da anca
CA2502284A1 (en) 2002-10-15 2004-04-29 Novartis Ag Bisphosphonates for the treatment of antheroscleorosis and devices comprising them
CN1802353A (zh) * 2002-12-30 2006-07-12 细胞基因公司 氟烷氧基取代的1,3－二氢－异吲哚化合物及其药物用途
US20060051407A1 (en) 2003-06-27 2006-03-09 Yoram Richter Method of treating ischemia-reperfusion injury
US10517883B2 (en) * 2003-06-27 2019-12-31 Zuli Holdings Ltd. Method of treating acute myocardial infarction
WO2005002545A1 (en) * 2003-06-27 2005-01-13 Biorest Ltd. Method of treating acute coronary syndromes
US20050119230A1 (en) * 2003-09-18 2005-06-02 Alexandra Glausch Pharmaceutical products comprising bisphosphonated
CN1852719A (zh) 2003-09-19 2006-10-25 辉瑞产品公司 包括2－亚烷基－19－去甲－维生素d衍生物和二膦酸盐的组合的药物组合物和方法
GB0327742D0 (en) * 2003-11-28 2003-12-31 Isis Innovation Novel uses of known drugs
AU2005275193A1 (en) * 2004-07-15 2006-02-23 Nanobac Life Sciences Methods and compositions for the administration of calcium chelators, bisphosphonates and/or citrate compounds and their pharmaceutical uses
US20060069068A1 (en) 2004-07-15 2006-03-30 Nanobac Pharmaceuticals, Inc. Methods and compositions for the treatment of diseases characterized by pathological calcification
US7473684B2 (en) * 2005-09-16 2009-01-06 Selamine Limited Bisphosphonate formulation
CA2648594C (en) * 2006-04-07 2012-10-16 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
EP1925621A1 (en) * 2006-11-27 2008-05-28 Novartis AG Crystalline forms of zoledronic acid
US20080146489A1 (en) 2006-12-15 2008-06-19 Pacetti Stephen D Regional delivery of therapeutic agents for the treatment of vascular diseases
WO2008116133A1 (en) 2007-03-21 2008-09-25 Duke University Medication kits and formulations for preventing, treating or reducing secondary fractures after previous fracture
EP2222636B1 (en) * 2007-12-21 2013-04-10 Ligand Pharmaceuticals Inc. Selective androgen receptor modulators (sarms) and uses thereof
CN101259133A (zh) * 2008-03-28 2008-09-10 王洪 唑来磷酸用于制备预防及治疗骨质疏松症的药物
EP2288378A4 (en) 2008-04-16 2011-12-14 Univ Utah Res Found PHARMACOLOGICAL TARGETING OF VASCULAR MALFORMATION

Also Published As

Publication number Publication date
US20120208786A1 (en) 2012-08-16
WO2011028737A3 (en) 2011-07-14
WO2011028737A8 (en) 2012-05-18
HRP20150496T1 (hr) 2015-08-14
DK2473172T3 (en) 2015-06-15
WO2011028737A2 (en) 2011-03-10
EP2473172A2 (en) 2012-07-11
CN105920023A (zh) 2016-09-07
PT2473172E (pt) 2015-06-25
EP2473172A4 (en) 2013-01-16
HUE025737T2 (en) 2016-05-30
PL2473172T3 (pl) 2015-08-31
ES2537216T3 (es) 2015-06-03
US20180125869A1 (en) 2018-05-10
SMT201500124B (it) 2015-07-09
CN102639137A (zh) 2012-08-15
US9867838B2 (en) 2018-01-16
EP2473172B1 (en) 2015-04-08

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