SI2292231T1 - Terapevtsko sredstvo za stenozo spinalnega kanala - Google Patents

Terapevtsko sredstvo za stenozo spinalnega kanala

Info

Publication number
SI2292231T1
SI2292231T1 SI200931341T SI200931341T SI2292231T1 SI 2292231 T1 SI2292231 T1 SI 2292231T1 SI 200931341 T SI200931341 T SI 200931341T SI 200931341 T SI200931341 T SI 200931341T SI 2292231 T1 SI2292231 T1 SI 2292231T1
Authority
SI
Slovenia
Prior art keywords
therapeutic agent
spinal canal
canal stenosis
stenosis
spinal
Prior art date
Application number
SI200931341T
Other languages
English (en)
Inventor
Keiichi Kuwano
Original Assignee
Nippon Shinyaku Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co., Ltd. filed Critical Nippon Shinyaku Co., Ltd.
Publication of SI2292231T1 publication Critical patent/SI2292231T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
SI200931341T 2008-06-23 2009-06-22 Terapevtsko sredstvo za stenozo spinalnega kanala SI2292231T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008162638 2008-06-23
PCT/JP2009/061285 WO2009157396A1 (ja) 2008-06-23 2009-06-22 脊柱管狭窄症治療剤
EP09770106.4A EP2292231B1 (en) 2008-06-23 2009-06-22 Therapeutic agent for spinal canal stenosis

Publications (1)

Publication Number Publication Date
SI2292231T1 true SI2292231T1 (sl) 2016-03-31

Family

ID=41444462

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200931341T SI2292231T1 (sl) 2008-06-23 2009-06-22 Terapevtsko sredstvo za stenozo spinalnega kanala

Country Status (15)

Country Link
US (1) US8629145B2 (sl)
EP (1) EP2292231B1 (sl)
JP (1) JP5527205B2 (sl)
KR (1) KR101626168B1 (sl)
CN (3) CN102065863A (sl)
CA (1) CA2728089C (sl)
CY (1) CY1117080T1 (sl)
DK (1) DK2292231T3 (sl)
ES (1) ES2557303T3 (sl)
HR (1) HRP20151443T1 (sl)
HU (1) HUE025885T2 (sl)
PL (1) PL2292231T3 (sl)
PT (1) PT2292231E (sl)
SI (1) SI2292231T1 (sl)
WO (1) WO2009157396A1 (sl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104761509A (zh) * 2008-02-28 2015-07-08 日本新药株式会社 纤维化抑制剂
PT2447254T (pt) 2009-06-26 2018-01-04 Nippon Shinyaku Co Ltd Cristais
WO2011024874A1 (ja) * 2009-08-26 2011-03-03 日本新薬株式会社 塩基付加塩
IL310203A (en) 2015-12-02 2024-03-01 Nippon Shinyaku Co Ltd Pharmaceutical preparation containing 2-{4-[N-(6,5-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide
CN109563055B (zh) * 2016-07-29 2021-12-24 成都苑东生物制药股份有限公司 氨基吡嗪类化合物或盐、异构体、其制备方法及用途
JOP20190204A1 (ar) 2017-03-08 2019-09-05 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على سيليكسيباغ
AR112842A1 (es) 2017-09-28 2019-12-18 Nippon Shinyaku Co Ltd Cristal de pirazina
US10407396B2 (en) * 2017-11-16 2019-09-10 Apotex Inc. Crystalline form of selexipag
MX2020004962A (es) 2017-11-16 2020-08-27 Nippon Shinyaku Co Ltd Preparacion de liberacion controlada.
IL292354A (en) 2019-10-23 2022-06-01 Actelion Pharmaceuticals Ltd A pharmaceutical preparation containing Selexifag
JP2023512273A (ja) 2020-01-31 2023-03-24 アクテリオン ファーマシューティカルズ リミテッド 制御放出セレキシパグ組成物
TW202239408A (zh) 2021-01-29 2022-10-16 瑞士商艾克泰聯製藥有限公司 包含二苯基吡𠯤衍生物的醫藥組成物
TW202241425A (zh) 2021-01-29 2022-11-01 瑞士商艾克泰聯製藥有限公司 用於製造二苯基吡𠯤衍生物之程序
EP4316489A1 (en) * 2021-03-31 2024-02-07 Nippon Shinyaku Co., Ltd. Therapeutic agent for gait disturbance
JP7010404B1 (ja) 2021-03-31 2022-02-10 日本新薬株式会社 歩行障害治療剤
WO2023131608A1 (en) 2022-01-04 2023-07-13 Actelion Pharmaceuticals Ltd Controlled release compositions
WO2023214059A1 (en) 2022-05-06 2023-11-09 Actelion Pharmaceuticals Ltd Diphenylpyrazine compounds as prodrugs
WO2024017964A1 (en) 2022-07-20 2024-01-25 Actelion Pharmaceuticals Ltd Injectable pharmaceutical composition comprising a diphenylpyrazine derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI316055B (sl) 2001-04-26 2009-10-21 Nippon Shinyaku Co Ltd
BR0307780A (pt) * 2002-02-19 2004-12-28 Ono Pharmaceutical Co Compostos derivados de piridazina fundida e medicamentos contendo os compostos como o ingrediente ativo
JP4497320B2 (ja) 2002-10-10 2010-07-07 小野薬品工業株式会社 内因性修復因子産生促進剤
CN104761509A (zh) * 2008-02-28 2015-07-08 日本新药株式会社 纤维化抑制剂

Also Published As

Publication number Publication date
EP2292231B1 (en) 2015-10-21
CA2728089C (en) 2017-04-11
CA2728089A1 (en) 2009-12-30
PL2292231T3 (pl) 2016-03-31
EP2292231A4 (en) 2012-03-28
CN105168218A (zh) 2015-12-23
ES2557303T3 (es) 2016-01-25
CN102065863A (zh) 2011-05-18
KR20110033125A (ko) 2011-03-30
DK2292231T3 (en) 2015-12-14
JP5527205B2 (ja) 2014-06-18
WO2009157396A1 (ja) 2009-12-30
JPWO2009157396A1 (ja) 2011-12-15
US8629145B2 (en) 2014-01-14
CY1117080T1 (el) 2017-04-05
KR101626168B1 (ko) 2016-05-31
HRP20151443T1 (hr) 2016-01-29
US20110105518A1 (en) 2011-05-05
EP2292231A1 (en) 2011-03-09
CN103690541A (zh) 2014-04-02
HUE025885T2 (en) 2016-05-30
PT2292231E (pt) 2015-12-31

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